(46 nodes) NAD binding network (Phytophthora ramorum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	H3G901_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (238 aa)
	H3HCX0_PHYRM	Uncharacterized protein. (360 aa)
	H3HCE9_PHYRM	Uncharacterized protein; Belongs to the histidinol dehydrogenase family. (420 aa)
	H3HAT4_PHYRM	2-Hacid_dh_C domain-containing protein. (396 aa)
	H3H867_PHYRM	Deacetylase sirtuin-type domain-containing protein. (281 aa)
	H3H347_PHYRM	3HCDH_N domain-containing protein. (274 aa)
	H3H260_PHYRM	Deacetylase sirtuin-type domain-containing protein. (338 aa)
	H3H1R9_PHYRM	2-Hacid_dh_C domain-containing protein. (169 aa)
	H3H1L0_PHYRM	Deacetylase sirtuin-type domain-containing protein. (380 aa)
	H3GUE2_PHYRM	Uncharacterized protein. (484 aa)
	H3GLH0_PHYRM	Deacetylase sirtuin-type domain-containing protein. (540 aa)
	H3GK34_PHYRM	2-Hacid_dh_C domain-containing protein. (620 aa)
	H3GJX9_PHYRM	Uncharacterized protein. (104 aa)
	H3GJX8_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
	H3GJ45_PHYRM	Uncharacterized protein. (119 aa)
	H3GIA7_PHYRM	PRA-CH domain-containing protein. (508 aa)
	H3GFN8_PHYRM	Uncharacterized protein. (610 aa)
	H3GC97_PHYRM	2-Hacid_dh_C domain-containing protein. (348 aa)
	H3GC88_PHYRM	2-Hacid_dh_C domain-containing protein. (376 aa)
	H3GC86_PHYRM	2-Hacid_dh_C domain-containing protein. (384 aa)
	H3GB43_PHYRM	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (454 aa)
	H3GB07_PHYRM	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (339 aa)
	H3GAZ7_PHYRM	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (505 aa)
	H3GAJ0_PHYRM	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (345 aa)
	H3GAI8_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (278 aa)
	H3GAI7_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (252 aa)
	H3GAE7_PHYRM	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (685 aa)
	H3GAA1_PHYRM	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (448 aa)
	H3GA90_PHYRM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (422 aa)
	H3G9S4_PHYRM	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa)
	H3G9I7_PHYRM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
	H3G9I6_PHYRM	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
	H3G964_PHYRM	Glyceraldehyde-3-phosphate dehydrogenase. (340 aa)
	H3G963_PHYRM	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	H3G902_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
	H3G900_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
	H3G8W2_PHYRM	UDP-glucose 6-dehydrogenase. (470 aa)
	H3G8S5_PHYRM	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (339 aa)
	H3G8I5_PHYRM	NAD(P)-bd_dom domain-containing protein. (379 aa)
	H3G874_PHYRM	Triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (589 aa)
	H3G7Q4_PHYRM	Malic_M domain-containing protein. (262 aa)
	H3G781_PHYRM	Semialdhyde_dh domain-containing protein. (334 aa)
	H3G6I2_PHYRM	2-Hacid_dh_C domain-containing protein. (181 aa)
	H3G695_PHYRM	Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
	H3G5N8_PHYRM	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (340 aa)
	H3G4Z8_PHYRM	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (292 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G4Z8_PHYRM	H3G695_PHYRM	H3G4Z8	H3G695	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G4Z8_PHYRM	H3G7Q4_PHYRM	H3G4Z8	H3G7Q4	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Malic_M domain-containing protein.	0.678
H3G4Z8_PHYRM	H3G874_PHYRM	H3G4Z8	H3G874	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.580
H3G4Z8_PHYRM	H3G963_PHYRM	H3G4Z8	H3G963	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G4Z8_PHYRM	H3G964_PHYRM	H3G4Z8	H3G964	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G4Z8_PHYRM	H3GAA1_PHYRM	H3G4Z8	H3GAA1	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.556
H3G4Z8_PHYRM	H3GAZ7_PHYRM	H3G4Z8	H3GAZ7	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.580
H3G4Z8_PHYRM	H3GC86_PHYRM	H3G4Z8	H3GC86	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.450
H3G4Z8_PHYRM	H3GC88_PHYRM	H3G4Z8	H3GC88	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.451
H3G4Z8_PHYRM	H3GC97_PHYRM	H3G4Z8	H3GC97	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.449
H3G4Z8_PHYRM	H3GFN8_PHYRM	H3G4Z8	H3GFN8	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.572
H3G4Z8_PHYRM	H3GK34_PHYRM	H3G4Z8	H3GK34	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.421
H3G4Z8_PHYRM	H3HAT4_PHYRM	H3G4Z8	H3HAT4	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.454
H3G5N8_PHYRM	H3G695_PHYRM	H3G5N8	H3G695	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G5N8_PHYRM	H3G7Q4_PHYRM	H3G5N8	H3G7Q4	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Malic_M domain-containing protein.	0.678
H3G5N8_PHYRM	H3G874_PHYRM	H3G5N8	H3G874	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.580
H3G5N8_PHYRM	H3G963_PHYRM	H3G5N8	H3G963	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G5N8_PHYRM	H3G964_PHYRM	H3G5N8	H3G964	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.580
H3G5N8_PHYRM	H3GAA1_PHYRM	H3G5N8	H3GAA1	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.556
H3G5N8_PHYRM	H3GAZ7_PHYRM	H3G5N8	H3GAZ7	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.580

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