(39 nodes) PTEN Regulation network (Phytophthora ramorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3GBZ7_PHYRM	Proteasome subunit alpha type. (249 aa)
	H3HEG2_PHYRM	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (291 aa)
	H3HEF1_PHYRM	Uncharacterized protein. (887 aa)
	H3HDS7_PHYRM	Non-specific serine/threonine protein kinase. (564 aa)
	H3HD88_PHYRM	RING-type domain-containing protein. (344 aa)
	H3HAD6_PHYRM	Uncharacterized protein. (268 aa)
	H3H725_PHYRM	Uncharacterized protein. (169 aa)
	H3H6T6_PHYRM	Uncharacterized protein. (237 aa)
	H3H423_PHYRM	DUF3437 domain-containing protein. (196 aa)
	H3H388_PHYRM	Uncharacterized protein. (400 aa)
	H3H2I7_PHYRM	WD_REPEATS_REGION domain-containing protein. (178 aa)
	H3H116_PHYRM	RING-type domain-containing protein. (398 aa)
	H3GXU8_PHYRM	Uncharacterized protein. (243 aa)
	H3GX93_PHYRM	Uncharacterized protein. (346 aa)
	H3GX22_PHYRM	Repressor of RNA polymerase III transcription. (232 aa)
	H3GVI3_PHYRM	Uncharacterized protein. (520 aa)
	H3GS57_PHYRM	PI31_Prot_N domain-containing protein. (347 aa)
	H3GRM6_PHYRM	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (568 aa)
	H3GPR2_PHYRM	Chromo domain-containing protein. (516 aa)
	H3GNU1_PHYRM	Uncharacterized protein. (292 aa)
	H3GG35_PHYRM	Uncharacterized protein. (377 aa)
	H3GCJ7_PHYRM	VEFS-Box domain-containing protein. (497 aa)
	H3GCJ0_PHYRM	Uncharacterized protein. (533 aa)
	H3GAQ1_PHYRM	Uncharacterized protein. (174 aa)
	H3GAN0_PHYRM	Uncharacterized protein. (211 aa)
	H3GAF7_PHYRM	WD_REPEATS_REGION domain-containing protein. (293 aa)
	H3GAE2_PHYRM	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
	H3G9J2_PHYRM	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (220 aa)
	H3G8Y0_PHYRM	Tr-type G domain-containing protein. (679 aa)
	H3G8T9_PHYRM	Ubiquitin-like domain-containing protein. (164 aa)
	H3G8I4_PHYRM	Proteasome subunit alpha type. (236 aa)
	H3G8A4_PHYRM	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (218 aa)
	H3G783_PHYRM	Uncharacterized protein. (321 aa)
	H3G5Z2_PHYRM	WD_REPEATS_REGION domain-containing protein. (1226 aa)
	H3G5U5_PHYRM	RPN2_C domain-containing protein; Belongs to the proteasome subunit S1 family. (981 aa)
	H3G5S7_PHYRM	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (234 aa)
	H3G5E1_PHYRM	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (607 aa)
	H3G5D8_PHYRM	Uncharacterized protein; Belongs to the protein kinase superfamily. (299 aa)
	H3G5C3_PHYRM	Uncharacterized protein; Belongs to the protein kinase superfamily. (300 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G5C3_PHYRM	H3G5Z2_PHYRM	H3G5C3	H3G5Z2	Uncharacterized protein; Belongs to the protein kinase superfamily.	WD_REPEATS_REGION domain-containing protein.	0.668
H3G5C3_PHYRM	H3G783_PHYRM	H3G5C3	H3G783	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.616
H3G5C3_PHYRM	H3GAF7_PHYRM	H3G5C3	H3GAF7	Uncharacterized protein; Belongs to the protein kinase superfamily.	WD_REPEATS_REGION domain-containing protein.	0.596
H3G5C3_PHYRM	H3GG35_PHYRM	H3G5C3	H3GG35	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5C3_PHYRM	H3H388_PHYRM	H3G5C3	H3H388	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5C3_PHYRM	H3H725_PHYRM	H3G5C3	H3H725	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5C3_PHYRM	H3HD88_PHYRM	H3G5C3	H3HD88	Uncharacterized protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.497
H3G5D8_PHYRM	H3G5Z2_PHYRM	H3G5D8	H3G5Z2	Uncharacterized protein; Belongs to the protein kinase superfamily.	WD_REPEATS_REGION domain-containing protein.	0.668
H3G5D8_PHYRM	H3G783_PHYRM	H3G5D8	H3G783	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.616
H3G5D8_PHYRM	H3GAF7_PHYRM	H3G5D8	H3GAF7	Uncharacterized protein; Belongs to the protein kinase superfamily.	WD_REPEATS_REGION domain-containing protein.	0.596
H3G5D8_PHYRM	H3GG35_PHYRM	H3G5D8	H3GG35	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5D8_PHYRM	H3H388_PHYRM	H3G5D8	H3H388	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5D8_PHYRM	H3H725_PHYRM	H3G5D8	H3H725	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.497
H3G5D8_PHYRM	H3HD88_PHYRM	H3G5D8	H3HD88	Uncharacterized protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.497
H3G5E1_PHYRM	H3G8T9_PHYRM	H3G5E1	H3G8T9	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin-like domain-containing protein.	0.656
H3G5S7_PHYRM	H3G5U5_PHYRM	H3G5S7	H3G5U5	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	RPN2_C domain-containing protein; Belongs to the proteasome subunit S1 family.	0.968
H3G5S7_PHYRM	H3G8A4_PHYRM	H3G5S7	H3G8A4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999
H3G5S7_PHYRM	H3G8I4_PHYRM	H3G5S7	H3G8I4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.998
H3G5S7_PHYRM	H3G8T9_PHYRM	H3G5S7	H3G8T9	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin-like domain-containing protein.	0.967
H3G5S7_PHYRM	H3GBZ7_PHYRM	H3G5S7	H3GBZ7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999

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