(31 nodes) Histidine metabolism network (Phytophthora ramorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	H3GQC7_PHYRM	Uncharacterized protein. (631 aa)
	H3HCE9_PHYRM	Uncharacterized protein; Belongs to the histidinol dehydrogenase family. (420 aa)
	H3HCB1_PHYRM	F-box domain-containing protein. (263 aa)
	H3HBM0_PHYRM	Uncharacterized protein. (299 aa)
	H3H3Z3_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (407 aa)
	H3GZX4_PHYRM	Uncharacterized protein. (494 aa)
	H3GRS6_PHYRM	N2227 domain-containing protein. (373 aa)
	H3GQ46_PHYRM	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (515 aa)
	H3GPA7_PHYRM	Uncharacterized protein. (754 aa)
	H3GMV9_PHYRM	Uncharacterized protein. (132 aa)
	H3GKY2_PHYRM	CbiA domain-containing protein. (294 aa)
	H3GKX9_PHYRM	CbiA domain-containing protein. (294 aa)
	H3GIA7_PHYRM	PRA-CH domain-containing protein. (508 aa)
	H3GI85_PHYRM	Aminotran_1_2 domain-containing protein. (366 aa)
	H3GGT2_PHYRM	Uncharacterized protein; Belongs to the HisA/HisF family. (260 aa)
	H3GED5_PHYRM	Uncharacterized protein. (450 aa)
	H3GBF2_PHYRM	Helicase C-terminal domain-containing protein. (883 aa)
	H3GAM5_PHYRM	Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (362 aa)
	H3GAK8_PHYRM	Uncharacterized protein. (649 aa)
	H3GAB1_PHYRM	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (514 aa)
	H3G8Y9_PHYRM	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (450 aa)
	H3G8T0_PHYRM	Uncharacterized protein. (757 aa)
	H3G8I6_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (489 aa)
	H3G8I3_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (496 aa)
	H3G8I2_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (490 aa)
	H3G8H1_PHYRM	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (545 aa)
	H3G893_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
	H3G865_PHYRM	Amidohydro-rel domain-containing protein. (433 aa)
	H3G5S9_PHYRM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (484 aa)
	H3G5E2_PHYRM	Uncharacterized protein. (423 aa)
	H3G5B2_PHYRM	Aminotran_1_2 domain-containing protein. (383 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G5B2_PHYRM	H3G8H1_PHYRM	H3G5B2	H3G8H1	Aminotran_1_2 domain-containing protein.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.959
H3G5B2_PHYRM	H3G8T0_PHYRM	H3G5B2	H3G8T0	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.842
H3G5B2_PHYRM	H3G8Y9_PHYRM	H3G5B2	H3G8Y9	Aminotran_1_2 domain-containing protein.	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.	0.996
H3G5B2_PHYRM	H3GBF2_PHYRM	H3G5B2	H3GBF2	Aminotran_1_2 domain-containing protein.	Helicase C-terminal domain-containing protein.	0.842
H3G5B2_PHYRM	H3GED5_PHYRM	H3G5B2	H3GED5	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.713
H3G5B2_PHYRM	H3GGT2_PHYRM	H3G5B2	H3GGT2	Aminotran_1_2 domain-containing protein.	Uncharacterized protein; Belongs to the HisA/HisF family.	0.884
H3G5B2_PHYRM	H3GIA7_PHYRM	H3G5B2	H3GIA7	Aminotran_1_2 domain-containing protein.	PRA-CH domain-containing protein.	0.977
H3G5B2_PHYRM	H3GMV9_PHYRM	H3G5B2	H3GMV9	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.842
H3G5B2_PHYRM	H3HBM0_PHYRM	H3G5B2	H3HBM0	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.933
H3G5B2_PHYRM	H3HCB1_PHYRM	H3G5B2	H3HCB1	Aminotran_1_2 domain-containing protein.	F-box domain-containing protein.	0.842
H3G5B2_PHYRM	H3HCE9_PHYRM	H3G5B2	H3HCE9	Aminotran_1_2 domain-containing protein.	Uncharacterized protein; Belongs to the histidinol dehydrogenase family.	0.989
H3G5E2_PHYRM	H3G865_PHYRM	H3G5E2	H3G865	Uncharacterized protein.	Amidohydro-rel domain-containing protein.	0.928
H3G5E2_PHYRM	H3GED5_PHYRM	H3G5E2	H3GED5	Uncharacterized protein.	Uncharacterized protein.	0.944
H3G5S9_PHYRM	H3G893_PHYRM	H3G5S9	H3G893	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.568
H3G5S9_PHYRM	H3GAB1_PHYRM	H3G5S9	H3GAB1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.520
H3G5S9_PHYRM	H3GQ46_PHYRM	H3G5S9	H3GQ46	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.520
H3G865_PHYRM	H3G5E2_PHYRM	H3G865	H3G5E2	Amidohydro-rel domain-containing protein.	Uncharacterized protein.	0.928
H3G865_PHYRM	H3GAK8_PHYRM	H3G865	H3GAK8	Amidohydro-rel domain-containing protein.	Uncharacterized protein.	0.928
H3G865_PHYRM	H3GED5_PHYRM	H3G865	H3GED5	Amidohydro-rel domain-containing protein.	Uncharacterized protein.	0.824
H3G893_PHYRM	H3G5S9_PHYRM	H3G893	H3G5S9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.568

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