STRINGSTRING
AOR31162.1 AOR31162.1 AOR31525.1 AOR31525.1 hemE hemE AOR34359.1 AOR34359.1 tig tig AOR34175.1 AOR34175.1 AOR34166.1 AOR34166.1 AOR34086.1 AOR34086.1 AOR37318.1 AOR37318.1 AOR33946.1 AOR33946.1 AOR33945.1 AOR33945.1 AOR33451.1 AOR33451.1 AOR33375.1 AOR33375.1 AOR33370.1 AOR33370.1 AOR33286.1 AOR33286.1 AOR33092.1 AOR33092.1 AOR33061.1 AOR33061.1 AOR32939.1 AOR32939.1 hemA hemA hemC hemC AOR32832.1 AOR32832.1 AOR32824.1 AOR32824.1 AOR32806.1 AOR32806.1 hemL hemL map-2 map-2 BFF78_16985 BFF78_16985 AOR32327.1 AOR32327.1 AOR32324.1 AOR32324.1 AOR37095.1 AOR37095.1 AOR32097.1 AOR32097.1 AOR32058.1 AOR32058.1 gltX gltX AOR31779.1 AOR31779.1 AOR31695.1 AOR31695.1 hemH hemH AOR31602.1 AOR31602.1 AOR31494.1 AOR31494.1 AOR31493.1 AOR31493.1 AOR31423.1 AOR31423.1 AOR31332.1 AOR31332.1 map map BFF78_08850 BFF78_08850 AOR31112.1 AOR31112.1 pqqE pqqE AOR36964.1 AOR36964.1 AOR30830.1 AOR30830.1 AOR30729.1 AOR30729.1 AOR30680.1 AOR30680.1 AOR30674.1 AOR30674.1 AOR30673.1 AOR30673.1 AOR30602.1 AOR30602.1 AOR30363.1 AOR30363.1 AOR30266.1 AOR30266.1 AOR30241.1 AOR30241.1 AOR36644.1 AOR36644.1 AOR37645.1 AOR37645.1 AOR37616.1 AOR37616.1 hemC-2 hemC-2 AOR36155.1 AOR36155.1 AOR36109.1 AOR36109.1 AOR36107.1 AOR36107.1 AOR36064.1 AOR36064.1 AOR36063.1 AOR36063.1 AOR37582.1 AOR37582.1 AOR36038.1 AOR36038.1 AOR37560.1 AOR37560.1 rlmG rlmG AOR35867.1 AOR35867.1 AOR35858.1 AOR35858.1 AOR37547.1 AOR37547.1 AOR35792.1 AOR35792.1 AOR35703.1 AOR35703.1 AOR35387.1 AOR35387.1 AOR35386.1 AOR35386.1 AOR35385.1 AOR35385.1 AOR35200.1 AOR35200.1 cobD cobD cobQ cobQ AOR35080.1 AOR35080.1 AOR35079.1 AOR35079.1 AOR35078.1 AOR35078.1 cobB cobB AOR37454.1 AOR37454.1 AOR35075.1 AOR35075.1 AOR35074.1 AOR35074.1 AOR35073.1 AOR35073.1 AOR37453.1 AOR37453.1 AOR35072.1 AOR35072.1 AOR35001.1 AOR35001.1 ctaB ctaB AOR34844.1 AOR34844.1 AOR34825.1 AOR34825.1 AOR34778.1 AOR34778.1 cobT cobT cobS cobS AOR34760.1 AOR34760.1 map-3 map-3 AOR34693.1 AOR34693.1 AOR34658.1 AOR34658.1 AOR34498.1 AOR34498.1 AOR37372.1 AOR37372.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOR31162.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
AOR31525.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (664 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (352 aa)
AOR34359.1B12-binding domain-containing radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (462 aa)
AOR34175.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AOR34166.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AOR34086.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AOR37318.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AOR33946.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AOR33945.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
AOR33451.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AOR33375.1PPOX class F420-dependent enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AOR33370.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
AOR33286.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
AOR33092.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
AOR33061.1Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
AOR32939.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (507 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (562 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (319 aa)
AOR32832.1Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
AOR32824.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (330 aa)
AOR32806.1Peptidase M55; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
map-2Type I methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (278 aa)
BFF78_16985Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
AOR32327.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (469 aa)
AOR32324.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
AOR37095.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
AOR32097.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AOR32058.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (472 aa)
AOR31779.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
AOR31695.1DUF4937 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (375 aa)
AOR31602.1B12-binding domain-containing radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AOR31494.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (491 aa)
AOR31493.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
AOR31423.1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AOR31332.1Alpha-1-antitrypsin; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
mapType I methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (256 aa)
BFF78_08850Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (218 aa)
AOR31112.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
pqqEPyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (357 aa)
AOR36964.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
AOR30830.1PPOX class F420-dependent enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AOR30729.1Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AOR30680.1DNA starvation/stationary phase protection protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family. (161 aa)
AOR30674.1cobalt-precorrin-6A reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
AOR30673.1precorrin-6A synthase (deacetylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
AOR30602.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (401 aa)
AOR30363.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AOR30266.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
AOR30241.1PPOX class F420-dependent enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AOR36644.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AOR37645.1Pyrroloquinoline quinone biosynthesis protein PqqE; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AOR37616.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
hemC-2Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
AOR36155.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AOR36109.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (630 aa)
AOR36107.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AOR36064.1Pyrroloquinoline quinone biosynthesis protein PqqE; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
AOR36063.1Pyrroloquinoline quinone biosynthesis protein PqqD; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
AOR37582.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AOR36038.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
AOR37560.1DUF4865 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
rlmG50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (377 aa)
AOR35867.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AOR35858.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AOR37547.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1280 aa)
AOR35792.1glutamate--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AOR35703.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
AOR35387.1uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (410 aa)
AOR35386.15,6-dimethylbenzimidazole synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1410 aa)
AOR35385.1Precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
AOR35200.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa)
AOR35080.1Cobaltochelatase subunit CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. (1217 aa)
AOR35079.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
AOR35078.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (459 aa)
AOR37454.1Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (249 aa)
AOR35075.1Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AOR35074.1precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AOR35073.1precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
AOR37453.1precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AOR35072.1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
AOR35001.1Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (318 aa)
AOR34844.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AOR34825.1Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa)
AOR34778.1Adenosylcobinamide kinase/adenosylcobinamide phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (357 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (261 aa)
AOR34760.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
map-3Type I methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (285 aa)
AOR34693.1Heme oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
AOR34658.1Bifunctional RNase H/acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AOR34498.1Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AOR37372.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (410 aa)
Your Current Organism:
Streptomyces puniciscabiei
NCBI taxonomy Id: 164348
Other names: KACC 20253, LMG 21391, LMG:21391, S. puniciscabiei, Streptomyces puniciscabiei Park et al. 2003, Streptomyces sp. S77, strain S77
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