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AKQ42999.2 AKQ42999.2 AKQ43039.2 AKQ43039.2 AKQ40974.1 AKQ40974.1 AKQ43046.1 AKQ43046.1 AKQ41083.1 AKQ41083.1 sucC sucC AKQ43107.1 AKQ43107.1 AKQ41322.1 AKQ41322.1 AKQ43126.2 AKQ43126.2 AKQ41415.1 AKQ41415.1 purU purU AKQ43215.2 AKQ43215.2 AKQ41668.1 AKQ41668.1 AKQ41670.1 AKQ41670.1 AKQ43216.1 AKQ43216.1 AKQ41676.1 AKQ41676.1 AKQ41873.2 AKQ41873.2 AKQ41874.1 AKQ41874.1 AKQ41875.2 AKQ41875.2 sucD sucD mdh mdh AKQ41919.1 AKQ41919.1 accD accD AKQ41970.2 AKQ41970.2 AKQ43286.2 AKQ43286.2 AKQ41985.1 AKQ41985.1 AKQ43292.2 AKQ43292.2 AKQ41995.1 AKQ41995.1 AKQ42006.1 AKQ42006.1 AKQ43295.2 AKQ43295.2 AKQ42007.1 AKQ42007.1 AKQ42035.1 AKQ42035.1 AKQ42036.1 AKQ42036.1 acsA acsA AKQ42101.2 AKQ42101.2 accA accA AKQ42190.1 AKQ42190.1 AKQ42220.1 AKQ42220.1 pdhA pdhA AKQ42239.1 AKQ42239.1 AKQ43365.1 AKQ43365.1 AKQ43366.2 AKQ43366.2 AKQ42581.1 AKQ42581.1 AKQ42636.1 AKQ42636.1 AKQ43431.2 AKQ43431.2 AKQ42706.1 AKQ42706.1 AKQ42843.2 AKQ42843.2 gcvH gcvH gcvPA gcvPA AKQ42846.1 AKQ42846.1 AKQ42892.1 AKQ42892.1 AKQ42893.1 AKQ42893.1 AKQ42894.1 AKQ42894.1 AKQ42895.1 AKQ42895.1 AKQ42896.1 AKQ42896.1 AKQ43484.2 AKQ43484.2 AKQ43489.2 AKQ43489.2 ANC50530.1 ANC50530.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ42999.2Glutamate synthase; Belongs to the glutamate synthase family. (381 aa)
AKQ43039.2Glutamate synthase large subunit. (1530 aa)
AKQ40974.1Glutamate synthase, NADH/NADPH small subunit. (478 aa)
AKQ43046.1Glutamate dehydrogenase. (1576 aa)
AKQ41083.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (519 aa)
sucCmalate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa)
AKQ43107.1NADP-dependent malic enzyme. (753 aa)
AKQ41322.1Dihydrolipoamide dehydrogenase. (161 aa)
AKQ43126.2Aldehyde dehydrogenase. (500 aa)
AKQ41415.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (890 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
AKQ43215.2NADH dehydrogenase (ubiquinone), 24 kDa subunit. (192 aa)
AKQ41668.1NAD-dependent formate dehydrogenase beta subunit. (509 aa)
AKQ41670.1NAD-dependent formate dehydrogenase alpha subunit. (947 aa)
AKQ43216.1Methylmalonate-semialdehyde dehydrogenase, putative. (499 aa)
AKQ41676.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (290 aa)
AKQ41873.22-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase. (473 aa)
AKQ41874.1Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (413 aa)
AKQ41875.2Alpha-ketoglutarate decarboxylase. (911 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AKQ41919.1Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa)
AKQ41970.2FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (444 aa)
AKQ43286.2Succinate dehydrogenase, cytochrome b subunit. (150 aa)
AKQ41985.1Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (614 aa)
AKQ43292.22-oxoglutarate ferredoxin oxidoreductase alpha subunit. (645 aa)
AKQ41995.12-oxoglutarate ferredoxin oxidoreductase beta subunit. (344 aa)
AKQ42006.12-oxoisovalerate dehydrogenase (alpha subunit). (430 aa)
AKQ43295.22-oxoisovalerate dehydrogenase (beta subunit). (353 aa)
AKQ42007.1Branched-chain alpha-keto acid dehydrogenase subunit E2. (445 aa)
AKQ42035.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
AKQ42036.1acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
acsAPutative acetyl-coenzyme a synthetase protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (641 aa)
AKQ42101.2acyl-CoA synthetase domain-containing protein. (715 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
AKQ42190.1Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (261 aa)
AKQ42220.1Type II citrate synthase; Belongs to the citrate synthase family. (428 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (365 aa)
AKQ42239.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (461 aa)
AKQ43365.1Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (431 aa)
AKQ43366.2Pyruvate dehydrogenase complex, E3 component, lipoamidedehydrogenase, putative. (474 aa)
AKQ42581.1NAD-dependent aldehyde dehydrogenase. (460 aa)
AKQ42636.1Glutamine synthetase. (469 aa)
AKQ43431.2Oxidoreductase. (299 aa)
AKQ42706.1acyl-CoA synthetase. (705 aa)
AKQ42843.2Glycine cleavage system aminomethyltransferase T. (393 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (453 aa)
AKQ42846.1Glycine dehydrogenase subunit 2. (521 aa)
AKQ42892.1Carbamoyl-phosphate synthase L chain, ATP-binding. (678 aa)
AKQ42893.1methylmalonyl-CoA mutase. (719 aa)
AKQ42894.1methylmalonyl-CoA epimerase. (149 aa)
AKQ42895.1Hypothetical protein. (74 aa)
AKQ42896.1propionyl-CoA carboxylase subunit beta. (510 aa)
AKQ43484.2Succinate dehydrogenase. (116 aa)
AKQ43489.2Succinate-semialdehyde dehdyrogenase; Belongs to the aldehyde dehydrogenase family. (492 aa)
ANC50530.1Hypothetical protein. (69 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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