STRINGSTRING
AKQ41083.1 AKQ41083.1 sucC sucC AKQ43107.1 AKQ43107.1 AKQ41322.1 AKQ41322.1 AKQ43126.2 AKQ43126.2 AKQ41415.1 AKQ41415.1 purU purU AKQ43215.2 AKQ43215.2 AKQ41668.1 AKQ41668.1 AKQ41670.1 AKQ41670.1 AKQ41873.2 AKQ41873.2 AKQ41874.1 AKQ41874.1 AKQ41875.2 AKQ41875.2 sucD sucD mdh mdh AKQ41919.1 AKQ41919.1 AKQ43286.2 AKQ43286.2 AKQ41985.1 AKQ41985.1 AKQ42006.1 AKQ42006.1 AKQ43295.2 AKQ43295.2 AKQ42007.1 AKQ42007.1 AKQ42190.1 AKQ42190.1 AKQ42220.1 AKQ42220.1 pdhA pdhA AKQ42239.1 AKQ42239.1 AKQ43365.1 AKQ43365.1 AKQ43366.2 AKQ43366.2 AKQ42581.1 AKQ42581.1 AKQ43484.2 AKQ43484.2 AKQ43489.2 AKQ43489.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ41083.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (519 aa)
sucCmalate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa)
AKQ43107.1NADP-dependent malic enzyme. (753 aa)
AKQ41322.1Dihydrolipoamide dehydrogenase. (161 aa)
AKQ43126.2Aldehyde dehydrogenase. (500 aa)
AKQ41415.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (890 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
AKQ43215.2NADH dehydrogenase (ubiquinone), 24 kDa subunit. (192 aa)
AKQ41668.1NAD-dependent formate dehydrogenase beta subunit. (509 aa)
AKQ41670.1NAD-dependent formate dehydrogenase alpha subunit. (947 aa)
AKQ41873.22-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase. (473 aa)
AKQ41874.1Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (413 aa)
AKQ41875.2Alpha-ketoglutarate decarboxylase. (911 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AKQ41919.1Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)
AKQ43286.2Succinate dehydrogenase, cytochrome b subunit. (150 aa)
AKQ41985.1Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (614 aa)
AKQ42006.12-oxoisovalerate dehydrogenase (alpha subunit). (430 aa)
AKQ43295.22-oxoisovalerate dehydrogenase (beta subunit). (353 aa)
AKQ42007.1Branched-chain alpha-keto acid dehydrogenase subunit E2. (445 aa)
AKQ42190.1Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (261 aa)
AKQ42220.1Type II citrate synthase; Belongs to the citrate synthase family. (428 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (365 aa)
AKQ42239.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (461 aa)
AKQ43365.1Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (431 aa)
AKQ43366.2Pyruvate dehydrogenase complex, E3 component, lipoamidedehydrogenase, putative. (474 aa)
AKQ42581.1NAD-dependent aldehyde dehydrogenase. (460 aa)
AKQ43484.2Succinate dehydrogenase. (116 aa)
AKQ43489.2Succinate-semialdehyde dehdyrogenase; Belongs to the aldehyde dehydrogenase family. (492 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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