STRINGSTRING
rnhB rnhB uvrC uvrC AKQ42572.1 AKQ42572.1 ANC50508.1 ANC50508.1 rnhA rnhA AKQ40855.1 AKQ40855.1 AKQ40856.1 AKQ40856.1 AKQ43012.2 AKQ43012.2 AKQ40876.1 AKQ40876.1 ruvC ruvC AKQ40961.1 AKQ40961.1 AKQ43061.2 AKQ43061.2 AKQ41088.1 AKQ41088.1 AKQ41200.1 AKQ41200.1 AKQ41222.2 AKQ41222.2 rnpA rnpA nth nth AKQ41407.1 AKQ41407.1 AKQ41535.2 AKQ41535.2 AKQ41577.2 AKQ41577.2 AKQ41701.1 AKQ41701.1 uvrB uvrB ybeY ybeY uvrA uvrA rnc rnc rne rne AKQ43362.2 AKQ43362.2 AKQ42421.2 AKQ42421.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (212 aa)
uvrCExcinuclease complex nuclease subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (647 aa)
AKQ42572.1Hypothetical protein. (141 aa)
ANC50508.1Hypothetical protein. (547 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (146 aa)
AKQ40855.1Type I restriction-modification system endonuclease, putative. (1077 aa)
AKQ40856.1Putative type I site-specific restriction-modification system, S subunit. (426 aa)
AKQ43012.2Hypothetical protein. (313 aa)
AKQ40876.1Metallophosphoesterase. (370 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (154 aa)
AKQ40961.1Exodeoxyribonuclease III. (265 aa)
AKQ43061.2Ribonuclease T2 family protein; Belongs to the RNase T2 family. (250 aa)
AKQ41088.1Exodeoxyribonuclease III. (257 aa)
AKQ41200.1Metal-dependent hydrolase. (229 aa)
AKQ41222.2ATP-binding protein. (388 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (133 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (216 aa)
AKQ41407.1Hypothetical protein. (188 aa)
AKQ41535.2Hypothetical protein. (978 aa)
AKQ41577.2Hypothetical protein. (377 aa)
AKQ41701.1S1/P1 Nuclease. (285 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (728 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (168 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (971 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (231 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (925 aa)
AKQ43362.2Hypothetical protein. (167 aa)
AKQ42421.2HNH endonuclease. (75 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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