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| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (339 aa) |
| | AKQ40787.1 | Hypothetical protein. (335 aa) |
| | AKQ40805.1 | PAS/PAC sensor signal transduction histidine kinase. (512 aa) |
| | AKQ40840.1 | Putative inner-membrane protein traC. (847 aa) |
| | AKQ40855.1 | Type I restriction-modification system endonuclease, putative. (1077 aa) |
| | AKQ40859.2 | Hypothetical protein. (1975 aa) |
| | AKQ40861.1 | Hypothetical protein. (1243 aa) |
| | AKQ40894.1 | Aspartate kinase; Belongs to the aspartokinase family. (426 aa) |
| | AKQ40908.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (494 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (308 aa) |
| | AKQ40920.1 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (698 aa) |
| | AKQ40922.1 | Multidrug ABC transporter ATP-binding protein. (314 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa) |
| | gyrB | Type IIA topoisomerase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (848 aa) |
| | AKQ40943.1 | Cell division protein FtsK. (786 aa) |
| | rimK | Ribosomal protein S6 modification protein; Belongs to the RimK family. (301 aa) |
| | AKQ40947.2 | Hypothetical protein. (180 aa) |
| | AKQ40948.1 | ATP-binding protein. (482 aa) |
| | AKQ40964.1 | ATP-dependent DNA helicase RecQ. (598 aa) |
| | AKQ40969.1 | ABC-type multidrug transport system ATPase component. (604 aa) |
| | AKQ40982.1 | Hypothetical protein. (625 aa) |
| | AKQ40984.1 | Hypothetical protein. (277 aa) |
| | AKQ40985.2 | Hypothetical protein. (100 aa) |
| | AKQ40986.1 | ABC transporter ATP-binding protein. (551 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (839 aa) |
| | AKQ43045.2 | Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (930 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (695 aa) |
| | AKQ43047.2 | ABC transporter ATP-binding protein. (330 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa) |
| | AKQ41061.1 | Metal-sulfur cluster biosynthesis protein. (174 aa) |
| | AKQ41065.1 | FeS assembly ATPase SufC. (248 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa) |
| | AKQ41098.2 | Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (313 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (418 aa) |
| | AKQ41107.1 | Chromosome partitioning protein ATPase component. (258 aa) |
| | AKQ41112.1 | Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (317 aa) |
| | AKQ41122.1 | ATP-dependent DNA ligase. (536 aa) |
| | AKQ43072.1 | ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family. (796 aa) |
| | AKQ41130.2 | Nicotinic acid mononucleotide adenylyltransferase; Belongs to the NadD family. (211 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (388 aa) |
| | sucC | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (970 aa) |
| | AKQ41157.1 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (310 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (357 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa) |
| | AKQ41177.1 | ATPases involved in chromosome partitioning-like protein. (278 aa) |
| | AKQ41181.2 | ATP-dependent RNA helicase, DEAD/DEAH box family protein. (842 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (367 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (800 aa) |
| | queC | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (233 aa) |
| | AKQ41236.1 | cob(I)yrinic acid a, c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (191 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (873 aa) |
| | AKQ41268.1 | ABC transporter ATP-binding protein. (271 aa) |
| | hisS | histidyl-tRNA synthetase. (415 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa) |
| | AKQ41279.1 | Cell division cycle protein; Belongs to the AAA ATPase family. (768 aa) |
| | AKQ41282.2 | Protein-tyrosine kinase. (729 aa) |
| | groL | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (550 aa) |
| | groS | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (95 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (450 aa) |
| | AKQ41307.1 | Cell division protein. (306 aa) |
| | ftsE | ABC transporter related protein; Part of the ABC transporter FtsEX involved in cellular division. (241 aa) |
| | AKQ41314.1 | Rod shape-determining protein MreB. (345 aa) |
| | AKQ43129.2 | Chromosome partitioning protein ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (333 aa) |
| | AKQ41336.1 | Hypothetical protein. (165 aa) |
| | AKQ43138.2 | CpaF pilus assembly protein, ATPase CpaF. (463 aa) |
| | AKQ41354.2 | Hypothetical protein. (399 aa) |
| | AKQ41357.1 | Hypothetical protein. (559 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (641 aa) |
| | AKQ41368.2 | Sulfate adenylyltransferase subunit 2. (304 aa) |
| | ftsH | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (648 aa) |
| | AKQ41375.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (507 aa) |
| | AKQ41383.1 | ATPase AAA. (498 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (486 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (342 aa) |
| | AKQ41426.2 | Magnesium chelatase. (320 aa) |
| | AKQ41457.1 | ATPase FliI/YscN family. (445 aa) |
| | AKQ43169.2 | Hypothetical protein. (423 aa) |
| | AKQ41483.1 | Molybdate ABC transporter ATP-binding protein. (212 aa) |
| | AKQ41500.1 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (491 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase-like protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (322 aa) |
| | AKQ43192.2 | Glucokinase; Belongs to the bacterial glucokinase family. (347 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | AKQ41537.1 | Chromosome segregation protein SMC. (834 aa) |
| | AKQ41547.2 | Hypothetical protein. (2160 aa) |
| | AKQ41570.1 | (4Fe-4S)-binding protein. (849 aa) |
| | AKQ41600.1 | HAD ATPase, P-type, family IC. (885 aa) |
| | AKQ41619.2 | Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (292 aa) |
| | AKQ43204.2 | Hypothetical protein. (411 aa) |
| | AKQ41623.1 | Copper-translocating P-type ATPase. (803 aa) |
| | AKQ41625.2 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (820 aa) |
| | AKQ41649.1 | Haloacid dehalogenase. (736 aa) |
| | AKQ41653.1 | Copper/silver efflux P-type ATPase. (787 aa) |
| | AKQ41663.1 | Plasmid partitioning protein ParA. (239 aa) |
| | AKQ43222.2 | Hypothetical protein. (322 aa) |
| | bioD | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (207 aa) |
| | AKQ41717.1 | Macrolide ABC transporter ATP-binding protein. (240 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (728 aa) |
| | AKQ41737.1 | Hypothetical protein. (476 aa) |
| | AKQ41778.2 | Hypothetical protein. (481 aa) |
| | AKQ41786.1 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (461 aa) |
| | smc | Chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1140 aa) |
| | AKQ41801.1 | Phosphate starvation protein PhoH. (351 aa) |
| | adk | Adenylate monophosphate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | AKQ41881.1 | Ferrichrome ABC transporter ATP-binding protein. (241 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (971 aa) |
| | argG | Citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (412 aa) |
| | nadE | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (688 aa) |
| | recA | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (355 aa) |
| | alaS | AlaS, alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (890 aa) |
| | AKQ41927.1 | Response regulator receiver domain protein (CheY-like). (124 aa) |
| | AKQ41932.1 | DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (474 aa) |
| | AKQ43271.2 | DNA and RNA helicase. (781 aa) |
| | AKQ41935.1 | Hypothetical protein; Belongs to the folylpolyglutamate synthase family. (445 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa) |
| | cmk | Cytidylate kinase. (211 aa) |
| | AKQ41966.1 | UDP-N-acetylmuramate--alanine ligase. (480 aa) |
| | AKQ41973.1 | Hypothetical protein. (379 aa) |
| | AKQ41979.2 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (568 aa) |
| | AKQ42009.1 | Putative 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (194 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | AKQ42024.1 | Two component, sigma54 specific, transcriptional regulator, Fis family. (458 aa) |
| | AKQ42035.1 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa) |
| | AKQ42045.1 | Elongation factor 3. (609 aa) |
| | AKQ42051.2 | ATP-dependent helicase. (815 aa) |
| | dnaX | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (621 aa) |
| | lon | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (813 aa) |
| | acsA | Putative acetyl-coenzyme a synthetase protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (641 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (613 aa) |
| | AKQ42101.2 | acyl-CoA synthetase domain-containing protein. (715 aa) |
| | AKQ42108.1 | Circadian clock protein KaiC. (499 aa) |
| | AKQ42126.1 | DEAD/DEAH box helicase. (458 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa) |
| | AKQ42147.2 | Putative ATPase. (145 aa) |
| | AKQ42151.1 | ATP-dependent exonuclease V subunit beta; Belongs to the helicase family. UvrD subfamily. (1158 aa) |
| | secA | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (916 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (269 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1164 aa) |
| | AKQ42159.1 | ATP-dependent DNA helicase RecG. (690 aa) |
| | lolD | ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. (224 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (270 aa) |
| | nnrE | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (464 aa) |
| | AKQ42183.2 | Lipopolysaccharide biosynthesis protein. (492 aa) |
| | AKQ42184.2 | Putative exopolysaccharide biosynthesis protein. (334 aa) |
| | AKQ42188.1 | Asparagine synthase. (631 aa) |
| | AKQ42189.2 | Hypothetical protein. (355 aa) |
| | AKQ43340.1 | Phosphoribosylglycinamide synthetase. (334 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (259 aa) |
| | AKQ42218.1 | Hypothetical protein. (316 aa) |
| | gltX-2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa) |
| | pyrG | UTP--ammonia ligase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (948 aa) |
| | ychF | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) |
| | glyQ | glycyl-tRNA synthetase subunit alpha. (265 aa) |
| | glyS | glycyl-tRNA synthetase beta subunit. (748 aa) |
| | AKQ42259.1 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (889 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (411 aa) |
| | parE | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (663 aa) |
| | gshB | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (317 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (645 aa) |
| | dnaJ | DnaJ molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (371 aa) |
| | radA | Putative ATP-dependent serine protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (455 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (514 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (522 aa) |
| | AKQ42304.1 | Two-component response regulator. (461 aa) |
| | AKQ42306.1 | Chemotaxis protein CheY. (472 aa) |
| | AKQ43369.2 | Nitrogen regulatory signal transduction histidine kinase NtrB. (326 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (613 aa) |
| | AKQ42320.1 | Rod shape-determining protein MreB. (348 aa) |
| | AKQ42326.1 | Anti-sigma B factor RsbT. (333 aa) |
| | AKQ42327.1 | Hypothetical protein. (139 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1107 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (395 aa) |
| | nrdR | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (161 aa) |
| | AKQ42360.2 | Multidrug ABC transporter ATP-binding protein. (333 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (744 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (319 aa) |
| | pstB | Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (289 aa) |
| | AKQ42390.1 | Fused predicted transporter subunit of ABC superfamily: ATP-binding component. (557 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (556 aa) |
| | AKQ42399.2 | DNA helicase. (928 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (480 aa) |
| | priA | Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (714 aa) |
| | atpA | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (509 aa) |
| | atpG | F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa) |
| | atpD | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (485 aa) |
| | AKQ42427.2 | Pilus assembly protein CpaF. (497 aa) |
| | AKQ42441.1 | Sigma-54 dependent DNA-binding response regulator. (472 aa) |
| | parC | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (765 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (548 aa) |
| | AKQ43397.2 | HPr protein serine kinase. (139 aa) |
| | AKQ42460.1 | Hypothetical protein; Displays ATPase and GTPase activities. (302 aa) |
| | AKQ43401.2 | Aerobic cobaltochelatase subunit CobS. (329 aa) |
| | AKQ42473.2 | DnaJ-class molecular chaperone. (145 aa) |
| | hisG | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (231 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (293 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (269 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase small subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (84 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (365 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | AKQ42522.1 | Hypothetical protein. (284 aa) |
| | tdk | Thymidine kinase. (193 aa) |
| | AKQ42558.1 | Transcriptional regulator. (344 aa) |
| | recF | Recombinational DNA repair ATPase; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (365 aa) |
| | AKQ42587.1 | ABC transporter related protein. (242 aa) |
| | AKQ42594.1 | ATPase AAA. (442 aa) |
| | AKQ42597.2 | Hypothetical protein. (177 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa) |
| | ftsA | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (431 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (325 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (474 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (448 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (489 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (490 aa) |
| | AKQ43428.2 | ABC-type transport system ATPase component. (159 aa) |
| | AKQ42636.1 | Glutamine synthetase. (469 aa) |
| | argS | arginyl-tRNA synthetase. (582 aa) |
| | thrB | Hypothetical protein; Belongs to the pseudomonas-type ThrB family. (322 aa) |
| | AKQ42660.1 | Pilus assembly protein CpaE. (434 aa) |
| | clpB | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (859 aa) |
| | AKQ42667.1 | Ubiquinol-cytochrome C reductase. (449 aa) |
| | gatB | glutamyl-tRNA(gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (499 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (493 aa) |
| | gatC | asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (100 aa) |
| | AKQ42672.2 | Hypothetical protein. (579 aa) |
| | AKQ43435.2 | Iron ABC transporter ATP-binding protein. (294 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (918 aa) |
| | AKQ43436.2 | Hypothetical protein. (572 aa) |
| | clpX | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa) |
| | AKQ42706.1 | acyl-CoA synthetase. (705 aa) |
| | AKQ42725.1 | DnaJ-class molecular chaperone. (176 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphohydrolase. (114 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (221 aa) |
| | AKQ42763.2 | 3-methylcrotonyl-CoA carboxylase subunit alpha. (659 aa) |
| | AKQ42770.1 | Hypothetical protein. (841 aa) |
| | AKQ42790.1 | DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (588 aa) |
| | AKQ43462.2 | Glycosyl transferase family 1. (627 aa) |
| | AKQ42793.1 | E1-E2 type cation ATPase. (705 aa) |
| | AKQ42800.2 | Molecular chaperone Hsp70. (379 aa) |
| | AKQ43467.2 | Permease. (604 aa) |
| | AKQ42803.1 | ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (432 aa) |
| | AKQ43473.2 | Hypothetical protein. (1011 aa) |
| | AKQ42852.1 | Type IV secretion system protein B4, putative. (809 aa) |
| | AKQ42855.1 | Type VI secretion protein; Part of the Type IV secretion system. Belongs to the GSP E family. (340 aa) |
| | ppk | Polyphosphoric acid kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (728 aa) |
| | AKQ42892.1 | Carbamoyl-phosphate synthase L chain, ATP-binding. (678 aa) |
| | AKQ42901.2 | ATPase component of various ABC-type transport system. (562 aa) |
| | AKQ42940.1 | Hypothetical protein. (141 aa) |
| | AKQ42966.1 | Multidrug ABC transporter ATP-binding protein. (920 aa) |
| | AKQ43501.2 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa) |
| | AKQ42972.2 | Cation-transporting ATPase. (849 aa) |
| | AKQ43504.2 | ABC transporter ATP-binding protein. (293 aa) |
| | AKQ42973.1 | Histidine kinase. (386 aa) |
| | AKQ42977.1 | Copper/silver efflux P-type ATPase. (744 aa) |
| | AKQ42981.1 | Iron ABC transporter ATP-binding protein. (255 aa) |
| | ANC50327.1 | Hypothetical protein. (705 aa) |
| | ANC50328.1 | ABC transporter related protein. (479 aa) |
| | ANC50334.1 | Hypothetical protein. (312 aa) |
| | ANC50383.1 | Hypothetical protein. (772 aa) |
| | ANC50445.1 | ATPase. (856 aa) |
| | ANC50485.1 | Heat shock protein DnaJ domain-containing protein. (153 aa) |
| | ANC50493.1 | Hypothetical protein. (58 aa) |
| | ANC50538.1 | Hypothetical protein. (500 aa) |
| | ANC50541.1 | CoA-binding domain-containing protein. (686 aa) |
