STRINGSTRING
AKQ41087.1 AKQ41087.1 AKQ41089.1 AKQ41089.1 rsfS rsfS rplT rplT prfC prfC prfA prfA AKQ41315.1 AKQ41315.1 AKQ41318.1 AKQ41318.1 AKQ43129.2 AKQ43129.2 AKQ41375.1 AKQ41375.1 AKQ41383.1 AKQ41383.1 engB engB murJ murJ secB secB AKQ41406.2 AKQ41406.2 ruvA ruvA ruvB ruvB AKQ41445.2 AKQ41445.2 AKQ41448.1 AKQ41448.1 fliP fliP AKQ41451.2 AKQ41451.2 AKQ41465.1 AKQ41465.1 AKQ41466.1 AKQ41466.1 AKQ41471.1 AKQ41471.1 AKQ41472.1 AKQ41472.1 AKQ41476.1 AKQ41476.1 AKQ41477.1 AKQ41477.1 AKQ43173.2 AKQ43173.2 AKQ43176.2 AKQ43176.2 AKQ41537.1 AKQ41537.1 AKQ41675.1 AKQ41675.1 AKQ41730.1 AKQ41730.1 AKQ43232.2 AKQ43232.2 AKQ43235.2 AKQ43235.2 ctaG ctaG AKQ41782.2 AKQ41782.2 smc smc AKQ43245.2 AKQ43245.2 AKQ43257.2 AKQ43257.2 rlpA rlpA AKQ43271.2 AKQ43271.2 AKQ41935.1 AKQ41935.1 AKQ41966.1 AKQ41966.1 bamD bamD AKQ42010.1 AKQ42010.1 AKQ42044.1 AKQ42044.1 AKQ42055.1 AKQ42055.1 frr frr bamA bamA AKQ42072.1 AKQ42072.1 ccmC ccmC ccmE ccmE AKQ42081.1 AKQ42081.1 AKQ42084.1 AKQ42084.1 mltG mltG AKQ43319.2 AKQ43319.2 AKQ42115.1 AKQ42115.1 murI murI topA topA AKQ42144.1 AKQ42144.1 AKQ42148.1 AKQ42148.1 AKQ42151.1 AKQ42151.1 mfd mfd AKQ42159.1 AKQ42159.1 AKQ43340.1 AKQ43340.1 prfB prfB AKQ42226.1 AKQ42226.1 gyrA gyrA AKQ42250.1 AKQ42250.1 parE parE AKQ43363.1 AKQ43363.1 AKQ43367.2 AKQ43367.2 AKQ42296.1 AKQ42296.1 mrdB mrdB priA priA parC parC AKQ43395.2 AKQ43395.2 glmU glmU lptD lptD AKQ42511.2 AKQ42511.2 AKQ42519.1 AKQ42519.1 AKQ42567.1 AKQ42567.1 AKQ42572.1 AKQ42572.1 AKQ42591.1 AKQ42591.1 ftsZ ftsZ ftsQ ftsQ ddl ddl murB murB murC murC murG murG murD murD mraY mraY murF murF murE murE AKQ43428.2 AKQ43428.2 AKQ42630.1 AKQ42630.1 AKQ42649.1 AKQ42649.1 AKQ42657.1 AKQ42657.1 AKQ42678.1 AKQ42678.1 AKQ43435.2 AKQ43435.2 AKQ43436.2 AKQ43436.2 mtgA mtgA AKQ42746.1 AKQ42746.1 AKQ42788.1 AKQ42788.1 AKQ42806.1 AKQ42806.1 AKQ42815.1 AKQ42815.1 AKQ43473.2 AKQ43473.2 AKQ42848.1 AKQ42848.1 AKQ42868.1 AKQ42868.1 AKQ42889.1 AKQ42889.1 AKQ42981.1 AKQ42981.1 ANC50331.1 ANC50331.1 ANC50445.1 ANC50445.1 ANC50502.1 ANC50502.1 AKQ40859.2 AKQ40859.2 AKQ40861.1 AKQ40861.1 gyrB gyrB AKQ40952.1 AKQ40952.1 AKQ40955.1 AKQ40955.1 AKQ40959.1 AKQ40959.1 AKQ40964.1 AKQ40964.1 uppP uppP AKQ40973.2 AKQ40973.2 AKQ43040.2 AKQ43040.2 AKQ41000.1 AKQ41000.1 AKQ41004.1 AKQ41004.1 AKQ41060.2 AKQ41060.2 AKQ41061.1 AKQ41061.1 AKQ41064.1 AKQ41064.1 AKQ41065.1 AKQ41065.1 AKQ41067.1 AKQ41067.1 AKQ41082.1 AKQ41082.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ41087.1Heme biosynthesis protein HemY; Belongs to the HesB/IscA family. (108 aa)
AKQ41089.1Hydrolase. (225 aa)
rsfSRibosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (154 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (518 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (355 aa)
AKQ41315.1Hypothetical protein. (337 aa)
AKQ41318.1enoyl-CoA hydratase/isomerase. (255 aa)
AKQ43129.2Chromosome partitioning protein ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (333 aa)
AKQ41375.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (507 aa)
AKQ41383.1ATPase AAA. (498 aa)
engBRibosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (214 aa)
murJTransmembrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (532 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (188 aa)
AKQ41406.2Putative membrane-bound lytic murein transglycosylase A transmembrane protein. (387 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa)
ruvBHolliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (342 aa)
AKQ41445.2Hypothetical protein. (128 aa)
AKQ41448.1Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (265 aa)
fliPFlagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (255 aa)
AKQ41451.2Hypothetical protein. (60 aa)
AKQ41465.1Flagellar hook-associated protein 1 FlgK. (442 aa)
AKQ41466.1Peptidoglycan hydrolase. (91 aa)
AKQ41471.1Flagellar hook protein FlgE. (272 aa)
AKQ41472.1Flagellar hook capping protein. (114 aa)
AKQ41476.1Flagellar protein. (173 aa)
AKQ41477.1Hypothetical protein. (96 aa)
AKQ43173.2Flagellar biosynthesis protein FlhA. (702 aa)
AKQ43176.2Hypothetical protein. (477 aa)
AKQ41537.1Chromosome segregation protein SMC. (834 aa)
AKQ41675.1enoyl-CoA hydratase/isomerase family protein. (358 aa)
AKQ41730.1Hypothetical protein. (315 aa)
AKQ43232.2Hypothetical protein. (675 aa)
AKQ43235.2Thioredoxin-like protein. (197 aa)
ctaGPutative cytochrome c oxidase assembly transmembrane protein; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. (200 aa)
AKQ41782.2Pyrrolo-quinoline quinone. (454 aa)
smcChromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1140 aa)
AKQ43245.2Nitrogen-fixing NifU-like protein. (213 aa)
AKQ43257.2Hypothetical protein. (359 aa)
rlpAHypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (192 aa)
AKQ43271.2DNA and RNA helicase. (781 aa)
AKQ41935.1Hypothetical protein; Belongs to the folylpolyglutamate synthase family. (445 aa)
AKQ41966.1UDP-N-acetylmuramate--alanine ligase. (480 aa)
bamDDNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (264 aa)
AKQ42010.1Hypothetical protein. (104 aa)
AKQ42044.1Hypothetical protein. (426 aa)
AKQ42055.1Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
bamASurface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (918 aa)
AKQ42072.1Hypothetical protein. (222 aa)
ccmCABC-type transport system heme exporter; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (248 aa)
ccmECytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (153 aa)
AKQ42081.1Cytochrome c biogenesis factor. (653 aa)
AKQ42084.1Hypothetical protein. (233 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (322 aa)
AKQ43319.2Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
AKQ42115.1Hypothetical protein. (182 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (264 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (861 aa)
AKQ42144.1UDP-N-acetylglucosamine 1-carboxyvinyltransferase. (430 aa)
AKQ42148.1Aminoglycoside phosphotransferase. (330 aa)
AKQ42151.1ATP-dependent exonuclease V subunit beta; Belongs to the helicase family. UvrD subfamily. (1158 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1164 aa)
AKQ42159.1ATP-dependent DNA helicase RecG. (690 aa)
AKQ43340.1Phosphoribosylglycinamide synthetase. (334 aa)
prfBProtein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (375 aa)
AKQ42226.1Hypothetical protein. (122 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (948 aa)
AKQ42250.1Hypothetical protein. (382 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (663 aa)
AKQ43363.1Hypothetical protein. (133 aa)
AKQ43367.2Rare lipoprotein A. (331 aa)
AKQ42296.1D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (382 aa)
mrdBCell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (372 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (714 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (765 aa)
AKQ43395.2Aminotransferase. (340 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (468 aa)
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (772 aa)
AKQ42511.2PpiC-type peptidyl-prolyl cis-trans isomerase. (454 aa)
AKQ42519.1Hypothetical protein. (203 aa)
AKQ42567.1Fe-S metabolism protein SufE. (135 aa)
AKQ42572.1Hypothetical protein. (141 aa)
AKQ42591.1GTP-binding protein TypA/BipA. (606 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (553 aa)
ftsQCell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (303 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (325 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (319 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (474 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (422 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (448 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (356 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (489 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (490 aa)
AKQ43428.2ABC-type transport system ATPase component. (159 aa)
AKQ42630.1Cytochrome c-type biogenesis protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (220 aa)
AKQ42649.1Hypothetical protein. (238 aa)
AKQ42657.1Type IV prepilin peptidase, cpaA. (163 aa)
AKQ42678.1Molecular chaperone. (232 aa)
AKQ43435.2Iron ABC transporter ATP-binding protein. (294 aa)
AKQ43436.2Hypothetical protein. (572 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (223 aa)
AKQ42746.1Hypothetical protein. (83 aa)
AKQ42788.1enoyl-CoA hydratase. (350 aa)
AKQ42806.1Membrane protein SmpA. (153 aa)
AKQ42815.1Riboflavin synthase subunit alpha. (206 aa)
AKQ43473.2Hypothetical protein. (1011 aa)
AKQ42848.1Hypothetical protein. (525 aa)
AKQ42868.1NADH-ubiquinone oxidoreductase. (132 aa)
AKQ42889.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
AKQ42981.1Iron ABC transporter ATP-binding protein. (255 aa)
ANC50331.1Peptidase A24A, prepilin type IV. (166 aa)
ANC50445.1ATPase. (856 aa)
ANC50502.1Hypothetical protein. (181 aa)
AKQ40859.2Hypothetical protein. (1975 aa)
AKQ40861.1Hypothetical protein. (1243 aa)
gyrBType IIA topoisomerase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (848 aa)
AKQ40952.1Hypothetical protein. (185 aa)
AKQ40955.1Hypothetical protein. (524 aa)
AKQ40959.1Peptide chain release factor I. (134 aa)
AKQ40964.1ATP-dependent DNA helicase RecQ. (598 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (264 aa)
AKQ40973.2Hypothetical protein. (521 aa)
AKQ43040.2Hypothetical protein. (203 aa)
AKQ41000.1Exopolysaccharide biosynthesis protein, glycosyltransferase. (351 aa)
AKQ41004.1Hypothetical protein. (165 aa)
AKQ41060.2Hypothetical protein; Belongs to the HesB/IscA family. (120 aa)
AKQ41061.1Metal-sulfur cluster biosynthesis protein. (174 aa)
AKQ41064.1Hypothetical protein. (254 aa)
AKQ41065.1FeS assembly ATPase SufC. (248 aa)
AKQ41067.1Cysteine desulfarase. (493 aa)
AKQ41082.1Sensor histidine kinase. (394 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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