STRINGSTRING
AKQ41324.2 AKQ41324.2 AKQ40989.1 AKQ40989.1 aroE aroE AKQ41186.1 AKQ41186.1 AKQ43107.1 AKQ43107.1 zwf zwf AKQ41584.2 AKQ41584.2 AKQ41605.1 AKQ41605.1 AKQ41626.1 AKQ41626.1 AKQ41676.1 AKQ41676.1 gpsA gpsA AKQ43233.2 AKQ43233.2 leuB leuB mdh mdh AKQ41919.1 AKQ41919.1 AKQ41925.1 AKQ41925.1 AKQ41988.1 AKQ41988.1 guaB guaB AKQ42000.1 AKQ42000.1 dxr dxr ilvC ilvC AKQ42444.1 AKQ42444.1 hisD hisD pdxA pdxA AKQ42595.1 AKQ42595.1 murB murB AKQ43431.2 AKQ43431.2 AKQ42705.2 AKQ42705.2 AKQ42764.1 AKQ42764.1 AKQ43471.2 AKQ43471.2 AKQ42907.1 AKQ42907.1 AKQ42909.1 AKQ42909.1 AKQ42910.1 AKQ42910.1 AKQ42912.1 AKQ42912.1 AKQ42935.2 AKQ42935.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ41324.2Alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (400 aa)
AKQ40989.1dTDP-6-deoxy-L-mannose-dehydrogenase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (282 aa)
aroEHypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (292 aa)
AKQ41186.1Homoserine dehydrogenase. (435 aa)
AKQ43107.1NADP-dependent malic enzyme. (753 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (476 aa)
AKQ41584.2Hypothetical protein. (363 aa)
AKQ41605.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (336 aa)
AKQ41626.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (337 aa)
AKQ41676.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (290 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
AKQ43233.23-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (536 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AKQ41919.1Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)
AKQ41925.13-hydroxyacyl-CoA dehydrogenase. (776 aa)
AKQ41988.1Lactate dehydrogenase. (388 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (483 aa)
AKQ42000.1Ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (422 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (387 aa)
ilvCAlpha-keto-beta-hydroxylacyl reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AKQ42444.1Dehydrogenase. (401 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (319 aa)
AKQ42595.1UDP-glucose 6-dehydrogenase. (434 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (319 aa)
AKQ43431.2Oxidoreductase. (299 aa)
AKQ42705.23-alpha, 7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase. (279 aa)
AKQ42764.1Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (490 aa)
AKQ43471.2Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (323 aa)
AKQ42907.1Aryl-alcohol dehydrogenase. (365 aa)
AKQ42909.1Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (337 aa)
AKQ42910.13-isopropylmalate dehydrogenase. (355 aa)
AKQ42912.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
AKQ42935.2Putative 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (323 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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