STRINGSTRING
AKQ42929.1 AKQ42929.1 gyrB gyrB AKQ40958.1 AKQ40958.1 AKQ40988.1 AKQ40988.1 AKQ43055.2 AKQ43055.2 purE purE gpmA gpmA AKQ41179.1 AKQ41179.1 groL groL AKQ41315.1 AKQ41315.1 AKQ41343.1 AKQ41343.1 AKQ41369.1 AKQ41369.1 AKQ41381.2 AKQ41381.2 AKQ41430.1 AKQ41430.1 glmM glmM AKQ43207.2 AKQ43207.2 AKQ41782.2 AKQ41782.2 AKQ41789.1 AKQ41789.1 AKQ43244.1 AKQ43244.1 AKQ43252.2 AKQ43252.2 AKQ43273.2 AKQ43273.2 trpF trpF AKQ43288.1 AKQ43288.1 AKQ43293.2 AKQ43293.2 AKQ43307.2 AKQ43307.2 dapF dapF murI murI topA topA pgi pgi nnrE nnrE AKQ42230.1 AKQ42230.1 tpiA tpiA gyrA gyrA parE parE AKQ42285.1 AKQ42285.1 AKQ42350.2 AKQ42350.2 AKQ43372.2 AKQ43372.2 AKQ42356.2 AKQ42356.2 queA queA AKQ42946.1 AKQ42946.1 AKQ42362.1 AKQ42362.1 AKQ42436.1 AKQ42436.1 parC parC truA truA ANC50381.1 ANC50381.1 AKQ42476.1 AKQ42476.1 AKQ42511.2 AKQ42511.2 truB truB AKQ42673.1 AKQ42673.1 AKQ42676.1 AKQ42676.1 tig tig AKQ42695.1 AKQ42695.1 AKQ42715.2 AKQ42715.2 hisA hisA AKQ42746.1 AKQ42746.1 AKQ42876.2 AKQ42876.2 AKQ42893.1 AKQ42893.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKQ42929.12-hydroxychromene-2-carboxylate isomerase. (197 aa)
gyrBType IIA topoisomerase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (848 aa)
AKQ40958.1RNA pseudouridine synthase. (217 aa)
AKQ40988.1dTDP-4-dehydrorhamnose 3, 5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
AKQ43055.2Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa)
gpmA2, 3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (228 aa)
AKQ41179.1Phosphoglucomutase. (475 aa)
groLMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (550 aa)
AKQ41315.1Hypothetical protein. (337 aa)
AKQ41343.1Myo-inositol-1-phosphate synthase. (366 aa)
AKQ41369.1Putative mannose-6-phosphate isomerase. (268 aa)
AKQ41381.2UDP-galactose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (351 aa)
AKQ41430.1Prephenate dehydratase. (298 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
AKQ43207.2Phosphoglucomutase/phosphomannomutase family protein. (507 aa)
AKQ41782.2Pyrrolo-quinoline quinone. (454 aa)
AKQ41789.1Protein-disulfide isomerase. (251 aa)
AKQ43244.1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (154 aa)
AKQ43252.2Magnesium transporter ApaG. (159 aa)
AKQ43273.2Pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. (268 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (216 aa)
AKQ43288.1Peptidyl-prolyl cis-trans isomerase A. (216 aa)
AKQ43293.2UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (397 aa)
AKQ43307.2Chorismate mutase. (103 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (269 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (264 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (861 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (508 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (464 aa)
AKQ42230.1Peptidyl-prolyl isomerase. (643 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (948 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (663 aa)
AKQ42285.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (357 aa)
AKQ42350.2Ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. (170 aa)
AKQ43372.2Ribose 5-phosphate isomerase. (154 aa)
AKQ42356.2Chorismate mutase, putative. (90 aa)
queAS-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (343 aa)
AKQ42946.14-oxalocrotonoate tautomerase/isomerase; Belongs to the 4-oxalocrotonate tautomerase family. (69 aa)
AKQ42362.1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (234 aa)
AKQ42436.1Aspartate racemase. (231 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (765 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (254 aa)
ANC50381.1Hypothetical protein. (698 aa)
AKQ42476.1Peptidylprolyl isomerase. (163 aa)
AKQ42511.2PpiC-type peptidyl-prolyl cis-trans isomerase. (454 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (323 aa)
AKQ42673.1Putative peptidyl-prolyl isomerase. (193 aa)
AKQ42676.1Pseudouridylate synthase; Belongs to the pseudouridine synthase RluA family. (405 aa)
tigPeptidyl-prolyl cis-trans isomerase trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (524 aa)
AKQ42695.1Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (317 aa)
AKQ42715.2Peptidylprolyl isomerase. (347 aa)
hisAImidazole-4-carboxamide isomerase. (241 aa)
AKQ42746.1Hypothetical protein. (83 aa)
AKQ42876.2Mannose-1-phosphate guanylyltransferase. (335 aa)
AKQ42893.1methylmalonyl-CoA mutase. (719 aa)
Your Current Organism:
Erythrobacter atlanticus
NCBI taxonomy Id: 1648404
Other names: E. atlanticus, Erythrobacter atlanticus Zhuang et al. 2015, Erythrobacter sp. s21-N3, KCTC 42697, MCCC 1A00519, strain s21-N3
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