(7 nodes) Mixed, incl. PmbA/TldA metallopeptidase domain 1, and Nitrilase activity network (Methylophilus sp. TWE2)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pmbA	Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
	AKR44589.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. (185 aa)
	AKR44671.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
	AKR43641.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
	AKR43642.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1283 aa)
	AKR43643.1	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	tldD	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)

Your Current Organism:

Methylophilus sp. TWE2

NCBI taxonomy Id: 1662285
Other names: M. sp. TWE2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR43641.1	AKR43642.1	ACJ67_09535	ACJ67_09540	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.516
AKR43641.1	AKR43643.1	ACJ67_09535	ACJ67_09545	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.506
AKR43641.1	AKR44671.1	ACJ67_09535	ACJ67_09530	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
AKR43642.1	AKR43641.1	ACJ67_09540	ACJ67_09535	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.516
AKR43642.1	AKR43643.1	ACJ67_09540	ACJ67_09545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.716
AKR43642.1	AKR44671.1	ACJ67_09540	ACJ67_09530	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
AKR43642.1	tldD	ACJ67_09540	ACJ67_09550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.619
AKR43643.1	AKR43641.1	ACJ67_09545	ACJ67_09535	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.506
AKR43643.1	AKR43642.1	ACJ67_09545	ACJ67_09540	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.716
AKR43643.1	tldD	ACJ67_09545	ACJ67_09550	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.589
AKR44589.1	pmbA	ACJ67_04890	ACJ67_04885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family.	Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.611
AKR44671.1	AKR43641.1	ACJ67_09530	ACJ67_09535	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
AKR44671.1	AKR43642.1	ACJ67_09530	ACJ67_09540	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
pmbA	AKR44589.1	ACJ67_04885	ACJ67_04890	Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family.	0.611
pmbA	tldD	ACJ67_04885	ACJ67_09550	Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817
tldD	AKR43642.1	ACJ67_09550	ACJ67_09540	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.619
tldD	AKR43643.1	ACJ67_09550	ACJ67_09545	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.589
tldD	pmbA	ACJ67_09550	ACJ67_04885	Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817