(23 nodes) Hydrogenase (acceptor) activity, and Protein maturation network (Magnetospirillum sp. XM1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	hyaA	Hydrogenase 1, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (372 aa)
	hyaB	Hydrogenase 1, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (598 aa)
	hyaC	Hydrogenase 1, b-type cytochrome subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier. (240 aa)
	hyaD	Hydrogenase maturation protein hyaD; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (162 aa)
	hupS	Uptake hydrogenase small subunit; Function of strongly homologous gene; putative enzyme. (295 aa)
	hupL	Uptake hydrogenase large subunit; Function of strongly homologous gene; putative enzyme. (512 aa)
	XM1_2644	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (481 aa)
	XM1_2645	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (341 aa)
	XM1_3479	Hydrogenase expression/formation protein hupT; Function of strongly homologous gene; phenotype. (157 aa)
	hybO	Hydrogenase 2, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (376 aa)
	hybA	Hydrogenase 2 4Fe-4S ferredoxin-type component; Function of homologous gene experimentally demonstrated in an other organism; putative carrier. (339 aa)
	hybB	Function of strongly homologous gene; carrier. (401 aa)
	hybC	Hydrogenase 2, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
	XM1_3918	Maturation element for hydrogenase 2 (modular protein); Function of strongly homologous gene; factor. (205 aa)
	hypC	Hydrogenase expression/formation protein HypC; Function of homologous gene experimentally demonstrated in an other organism; factor. (77 aa)
	hupK	Hydrogenase expression/formation protein HupK; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (367 aa)
	hybF	Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (114 aa)
	hypB	GTP hydrolase involved in nickel liganding into hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (315 aa)
	hypF	Hydrogenase maturation factor; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (358 aa)
	hypC-2	Hydrogenase expression/formation protein HypC; Function of homologous gene experimentally demonstrated in an other organism; phenotype. (75 aa)
	hypD	Protein required for maturation of hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family. (378 aa)
	hypE	Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (349 aa)
	hoxX	Hydrogenase maturation factor HoxX; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the enoyl-CoA hydratase/isomerase family. (550 aa)

Your Current Organism:

Magnetospirillum sp. XM1

NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
XM1_2644	XM1_2645	XM1_2644	XM1_2645	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.998
XM1_2644	XM1_3479	XM1_2644	XM1_3479	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase expression/formation protein hupT; Function of strongly homologous gene; phenotype.	0.821
XM1_2644	XM1_3918	XM1_2644	XM1_3918	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Maturation element for hydrogenase 2 (modular protein); Function of strongly homologous gene; factor.	0.871
XM1_2644	hupK	XM1_2644	XM1_3920	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase expression/formation protein HupK; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.949
XM1_2644	hupL	XM1_2644	XM1_2236	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Uptake hydrogenase large subunit; Function of strongly homologous gene; putative enzyme.	0.912
XM1_2644	hupS	XM1_2644	XM1_2235	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Uptake hydrogenase small subunit; Function of strongly homologous gene; putative enzyme.	0.993
XM1_2644	hyaA	XM1_2644	XM1_0661	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase 1, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.993
XM1_2644	hyaB	XM1_2644	XM1_0662	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase 1, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.	0.925
XM1_2644	hyaC	XM1_2644	XM1_0663	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase 1, b-type cytochrome subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.	0.966
XM1_2644	hyaD	XM1_2644	XM1_0664	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase maturation protein hyaD; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.871
XM1_2644	hybB	XM1_2644	XM1_3916	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Function of strongly homologous gene; carrier.	0.486
XM1_2644	hybC	XM1_2644	XM1_3917	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase 2, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.	0.926
XM1_2644	hybF	XM1_2644	XM1_3921	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.871
XM1_2644	hybO	XM1_2644	XM1_3914	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase 2, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.993
XM1_2644	hypB	XM1_2644	XM1_3922	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	GTP hydrolase involved in nickel liganding into hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.719
XM1_2644	hypC-2	XM1_2644	XM1_3924	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase expression/formation protein HypC; Function of homologous gene experimentally demonstrated in an other organism; phenotype.	0.628
XM1_2644	hypD	XM1_2644	XM1_3925	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein required for maturation of hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family.	0.736
XM1_2644	hypE	XM1_2644	XM1_3926	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.645
XM1_2644	hypF	XM1_2644	XM1_3923	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hydrogenase maturation factor; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.526
XM1_2645	XM1_2644	XM1_2645	XM1_2644	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Uptake hydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.998