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| | nadA | Quinolinate synthase, subunit A(Quinolinate synthetase A,26-326); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (340 aa) |
| | ilvE | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (290 aa) |
| | dnaB | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (263 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ [Includes: Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (410 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa) |
| | rkpK | UDP-glucose 6-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (435 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (298 aa) |
| | metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1157 aa) |
| | leuC | 3-isopropylmalate dehydratase (isomerase), subunit with LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (369 aa) |
| | proB | Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (370 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa) |
| | mtnP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (295 aa) |
| | mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (362 aa) |
| | XM1_0378 | Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (512 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase [NADH] 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (267 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | pheA | Prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (289 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (274 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa) |
| | XM1_0596 | Homologs of previously reported genes of unknown function. (224 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (444 aa) |
| | XM1_0633 | Homologs of previously reported genes of unknown function. (99 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (306 aa) |
| | argH | Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (471 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (424 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa) |
| | hisE | Phosphoribosyl-ATP pyrophosphatase; Function of strongly homologous gene; enzyme. (109 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Function of strongly homologous gene; enzyme. (239 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (199 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | XM1_0892 | Putative Asparagine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (585 aa) |
| | XM1_0930 | Putative Asparagine synthase (glutamine-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (567 aa) |
| | XM1_0945 | Putative radical SAM domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (354 aa) |
| | XM1_0959 | Putative carbamoyl phosphate synthase-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (346 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme. (371 aa) |
| | XM1_0974 | 3-dehydroquinate synthetase; Function of strongly homologous gene; enzyme. (356 aa) |
| | XM1_0975 | Putative D-3-phosphoglycerate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa) |
| | XM1_0977 | Putative Fe-S oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (400 aa) |
| | asnB | Asparagine synthetase; Function of strongly homologous gene; enzyme. (626 aa) |
| | XM1_1010 | Putative Asparagine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (627 aa) |
| | XM1_1017 | Protein of unknown function; No homology to any previously reported sequences. (377 aa) |
| | XM1_1026 | Conserved protein of unknowm function; Homologs of previously reported genes of unknown function; Belongs to the membrane-bound acyltransferase family. (404 aa) |
| | XM1_1030 | Acyl carrier protein; Function of strongly homologous gene; carrier. (77 aa) |
| | XM1_1042 | Putative Asparagine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (630 aa) |
| | XM1_1051 | Putative Peptidoglycan O-acetyltransferase(Membrane bound O-acyl transferase, MBOAT,121-380); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (481 aa) |
| | XM1_1106 | Conserved hypothetical protein, Putative Zinc finger CDGSH-type domain-containing protein; Homologs of previously reported genes of unknown function. (79 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (284 aa) |
| | cysK | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit(Cysteine synthase A,18-316); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (319 aa) |
| | astC | Succinylornithine transaminase, PLP-dependent（Aminotransferase class-III,4-389） Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (389 aa) |
| | argF | Ornithine carbamoyltransferase（Aspartate/ornithine carbamoyltransferase,5-304） Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa) |
| | gltB | Glutamate synthase (NADPH) large chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1528 aa) |
| | gltD | Glutamate synthase, 4Fe-4S protein, small subunit; Function of strongly homologous gene; carrier. (471 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (180 aa) |
| | XM1_1298 | Asparagine synthetase（Asparagine synthase, glutamine-hydrolyzing,2-569） Function of strongly homologous gene; enzyme. (641 aa) |
| | folC | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. (434 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa) |
| | trpA | Tryptophan synthase alpha chain(Aldolase-type TIM barrel,2-265); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | trpB | Tryptophan synthase, beta subunit(Tryptophan synthase, beta chain,11-398); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase（Aldolase-type TIM barrel,4-211） Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. (213 aa) |
| | argG | Argininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa) |
| | tyrC | Protein TyrC(Prephenate dehydrogenase,23-281); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (296 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (363 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (394 aa) |
| | aroK-2 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (194 aa) |
| | aroB | 3-dehydroquinate synthase(3-dehydroquinate synthase AroB,18-361); Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (372 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (379 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. (278 aa) |
| | hom | Homoserine dehydrogenase(NAD(P)-binding domain,4-150;Homoserine dehydrogenase, catalytic139-317); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (429 aa) |
| | serB | Phosphoserine phosphatase(Phosphoserine phosphatase SerB,78-287); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (298 aa) |
| | serA2 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein(NAD(P)-binding domain,114-286); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa) |
| | XM1_1813 | Protein of unknown function; No homology to any previously reported sequences. (508 aa) |
| | XM1_1841 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (333 aa) |
| | XM1_1896 | Putative asparagine synthase(Asparagine synthase, glutamine-hydrolyzing,2-507); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (586 aa) |
| | cbbZ | Phosphoglycolate phosphatase（2-phosphoglycolate phosphatase, prokaryotic,8-218） Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (220 aa) |
| | ytkP | Cysteine synthase-like protein; Function of strongly homologous gene; enzyme. (334 aa) |
| | XM1_1992 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (383 aa) |
| | XM1_2037 | Putative Heme d1 biosynthesis radical SAM protein NirJ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (380 aa) |
| | XM1_2145 | Nitrous oxidase accessory protein; Homologs of previously reported genes of unknown function. (550 aa) |
| | XM1_2206 | Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (263 aa) |
| | GABA-TP | Putative Gamma aminobutyrate transaminase 1, mitochondrial; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa) |
| | XM1_2495 | Putative Beta-ketoacyl synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (208 aa) |
| | XM1_2498 | Putative 3-oxoacyl-(Acyl carrier protein) synthase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa) |
| | trpB-2 | Putative Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (454 aa) |
| | XM1_2693 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa) |
| | trpC | Putative Indole-3-glycerol phosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TrpC family. (271 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (343 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (372 aa) |
| | fabD | malonyl-CoA-[acyl-carrier-protein] transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (313 aa) |
| | acpP | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | fabF | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa) |
| | XM1_2883 | Putative isopropylmalate synthase (LeuA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (546 aa) |
| | XM1_3029 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (698 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa) |
| | XM1_3110 | Putative Dihydrodipicolinate synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family. (300 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein, methyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (351 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa) |
| | rocD | Ornithine aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (398 aa) |
| | XM1_3211 | Putative 2,5-diketo-D-gluconic acid reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (280 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | XM1_3262 | Putative Acetylornithine deacetylase (ArgE); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (403 aa) |
| | putA | Fused DNA-binding transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1039 aa) |
| | serS | seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. (616 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa) |
| | XM1_3318 | Binuclear zinc phosphodiesterase; Function of strongly homologous gene; enzyme. (274 aa) |
| | gltB-2 | Glutamate synthase [NADPH] small chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (478 aa) |
| | gltB-3 | Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1543 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (312 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (132 aa) |
| | folK | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (164 aa) |
| | oahs | O-acetylhomoserine (thiol)-lyase; Function of strongly homologous gene; enzyme. (430 aa) |
| | XM1_3495 | Putative NADPH quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (330 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | XM1_3519 | acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (149 aa) |
| | aroQ | 3-dehydroquinate dehydratase 2; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (155 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (318 aa) |
| | XM1_3568 | Putative 8-amino-7-oxononanoate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (392 aa) |
| | bioD | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (205 aa) |
| | bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | kdsA | 3-deoxy-D-manno-octulosonate 8-phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. (283 aa) |
| | argC | N-acetylglutamate gamma-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa) |
| | trpB-3 | Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (452 aa) |
| | matA | Malonyl-CoA decarboxylase; Function of strongly homologous gene; enzyme. (472 aa) |
| | lysC | Aspartokinase II alpha subunit (aa 1->408) and beta subunit (aa 246->408); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (406 aa) |
| | fabI-2 | Enoyl-[acyl-carrier-protein] reductase, NADH-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (272 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (363 aa) |
| | nifV | Homocitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (377 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (380 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa) |
| | folP | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (383 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (219 aa) |
| | hisD | Bifunctional histidinal dehydrogenase and histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (433 aa) |
| | thrC | Threonine synthase; Function of strongly homologous gene; enzyme. (467 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (552 aa) |
| | ilvH | Acetolactate synthase III, thiamin-dependent, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (171 aa) |
| | ilvC | Acetohydroxy acid isomeroreductase and 2-dehydropantoate 2-reductase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa) |
| | thrB | Homoserine kinase; Function of strongly homologous gene; enzyme; Belongs to the pseudomonas-type ThrB family. (331 aa) |
| | XM1_4591 | Putative O-acetylhomoserine (thiol)-lyase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (473 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1085 aa) |
| | carA | Carbamoyl phosphate synthetase small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. (406 aa) |
| | XM1_4702 | Putative coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (372 aa) |
| | XM1_4763 | Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); Function of strongly homologous gene; enzyme. (535 aa) |
