STRINGSTRING
trpC trpC KLT67331.1 KLT67331.1 KLT67348.1 KLT67348.1 KLT67609.1 KLT67609.1 KLT67394.1 KLT67394.1 KLT67611.1 KLT67611.1 KLT67431.1 KLT67431.1 KLT67432.1 KLT67432.1 hisB hisB hisH hisH hisF hisF aroQ aroQ KLT66848.1 KLT66848.1 queE queE KLT66876.1 KLT66876.1 uxuA uxuA KLT67052.1 KLT67052.1 KLT67075.1 KLT67075.1 KLT66560.1 KLT66560.1 dapA dapA KLT66742.1 KLT66742.1 KLT65816.1 KLT65816.1 KLT65903.1 KLT65903.1 eno eno rlpA rlpA ilvD ilvD leuC leuC leuD leuD ilvA ilvA hemE hemE KLT65984.1 KLT65984.1 KLT66021.1 KLT66021.1 KLT66028.1 KLT66028.1 KLT66054.1 KLT66054.1 KLT66055.1 KLT66055.1 KLT66173.1 KLT66173.1 KLT66176.1 KLT66176.1 KLT66347.1 KLT66347.1 KLT65350.1 KLT65350.1 KLT65356.1 KLT65356.1 aroC aroC trpA trpA trpB trpB KLT65453.1 KLT65453.1 KLT65536.1 KLT65536.1 metZ metZ KLT65591.1 KLT65591.1 KLT65671.1 KLT65671.1 KLT65709.1 KLT65709.1 KLT65741.1 KLT65741.1 KLT64520.1 KLT64520.1 mqnD mqnD KLT64544.1 KLT64544.1 lpxC lpxC KLT64604.1 KLT64604.1 psd psd KLT64799.1 KLT64799.1 murQ murQ fumC fumC argH argH KLT64885.1 KLT64885.1 panD panD KLT64980.1 KLT64980.1 KLT64997.1 KLT64997.1 KLT65007.1 KLT65007.1 KLT65009.1 KLT65009.1 KLT65011.1 KLT65011.1 KLT65310.1 KLT65310.1 KLT65148.1 KLT65148.1 nnrD nnrD dacA dacA KLT65339.1 KLT65339.1 hemH hemH mltG mltG KLT64242.1 KLT64242.1 KLT64251.1 KLT64251.1 mqnA mqnA KLT64271.1 KLT64271.1 tal tal KLT64300.1 KLT64300.1 KLT64332.1 KLT64332.1 araD araD KLT64416.1 KLT64416.1 KLT64417.1 KLT64417.1 KLT64423.1 KLT64423.1 KLT64459.1 KLT64459.1 KLT64008.1 KLT64008.1 gmd gmd KLT64052.1 KLT64052.1 ispF ispF pckA pckA KLT63933.1 KLT63933.1 purK purK KLT63816.1 KLT63816.1 KLT63648.1 KLT63648.1 KLT63649.1 KLT63649.1 KLT63654.1 KLT63654.1 KLT63673.1 KLT63673.1 KLT63591.1 KLT63591.1 KLT63602.1 KLT63602.1 nth nth ribBA ribBA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (260 aa)
KLT67331.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
KLT67348.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (352 aa)
KLT67609.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
KLT67394.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
KLT67611.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (256 aa)
KLT67431.1Ethanolamine ammonia-lyase; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
KLT67432.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (254 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (377 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (197 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (140 aa)
KLT66848.1Extradiol dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (207 aa)
KLT66876.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (389 aa)
KLT67052.1Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
KLT67075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (157 aa)
KLT66560.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
KLT66742.1Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
KLT65816.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa)
KLT65903.1Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
rlpALipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (126 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (560 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (193 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (341 aa)
KLT65984.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (322 aa)
KLT66021.1Secondary thiamine-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
KLT66028.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
KLT66054.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (921 aa)
KLT66055.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
KLT66173.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (424 aa)
KLT66176.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (433 aa)
KLT66347.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
KLT65350.1Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
KLT65356.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (255 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
KLT65453.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KLT65536.1Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (388 aa)
KLT65591.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
KLT65671.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
KLT65709.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
KLT65741.1Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
KLT64520.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
mqnD1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (283 aa)
KLT64544.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (475 aa)
lpxChydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (470 aa)
KLT64604.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (861 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (219 aa)
KLT64799.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (268 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
KLT64885.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
panDAspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (116 aa)
KLT64980.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
KLT64997.1Phosphosulfolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KLT65007.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KLT65009.1Altronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
KLT65011.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
KLT65310.1Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
KLT65148.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa)
nnrDCarbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (496 aa)
dacAMembrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (263 aa)
KLT65339.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (336 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (351 aa)
KLT64242.1Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
KLT64251.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
mqnARadical SAM protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (246 aa)
KLT64271.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa)
KLT64300.1hydroxymyristoyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
KLT64332.1Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
araDCatalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
KLT64416.1Polysaccharide lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
KLT64417.1Polysaccharide lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
KLT64423.1Dihydrodipicolinate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (310 aa)
KLT64459.1Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (305 aa)
KLT64008.1GDP-D-mannose dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (375 aa)
KLT64052.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (350 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (162 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (531 aa)
KLT63933.1DASH family cryptochrome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (465 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (379 aa)
KLT63816.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
KLT63648.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KLT63649.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
KLT63654.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. (611 aa)
KLT63673.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
KLT63591.1formamidopyrimidine-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
KLT63602.1Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (221 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (403 aa)
Your Current Organism:
Pedobacter sp. BMA
NCBI taxonomy Id: 1663685
Other names: P. sp. BMA
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