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ldh1 ldh1 ydaP ydaP BGLY_0661 BGLY_0661 BGLY_0768 BGLY_0768 acyP acyP BGLY_0870 BGLY_0870 acoL acoL BGLY_1313 BGLY_1313 BGLY_1332 BGLY_1332 pdhA pdhA pdhB pdhB pdhC pdhC pdhD pdhD pyc pyc yngH yngH BGLY_2304 BGLY_2304 BGLY_2308 BGLY_2308 BGLY_2315 BGLY_2315 dhaS dhaS leuA-2 leuA-2 bfmBC bfmBC accC1 accC1 accB accB BGLY_2929 BGLY_2929 BGLY_3092 BGLY_3092 ytbE ytbE leuA leuA mdh mdh pyk pyk accA accA accD accD ytsJ ytsJ ackA ackA ytcI ytcI acsA acsA malS malS pckA pckA fumC fumC yvgN yvgN yvcT yvcT maeA maeA mmgA mmgA pta pta BGLY_4456 BGLY_4456 mleA mleA BGLY_4600 BGLY_4600 BGLY_4675 BGLY_4675
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ldh1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
ydaPPyruvate oxidase; Belongs to the TPP enzyme family. (573 aa)
BGLY_0661Hypothetical protein. (123 aa)
BGLY_0768Malate dehydrogenase. (539 aa)
acyPAcylphosphatase. (103 aa)
BGLY_0870Branched-chain alpha-keto acid dehydrogenase subunit E2. (372 aa)
acoLDihydrolipoyl dehydrogenase. (455 aa)
BGLY_1313Hypothetical protein. (120 aa)
BGLY_1332Glyoxylase. (125 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta. (325 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (442 aa)
pdhDDihydrolipoyl dehydrogenase. (470 aa)
pycPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1147 aa)
yngHacetyl-CoA carboxylase biotin carboxylase subunit. (446 aa)
BGLY_2304acetyl-CoA carboxylase biotin carboxyl carrier protein subunit. (70 aa)
BGLY_2308acetate-CoA ligase. (647 aa)
BGLY_2315Formate C-acetyltransferase. (741 aa)
dhaSPutative aldehyde dehydrogenase DhaS; Belongs to the aldehyde dehydrogenase family. (494 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (432 aa)
bfmBCDihydrolipoyl dehydrogenase. (473 aa)
accC1Biotin carboxylase 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
accBacetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
BGLY_2929Hypothetical protein. (212 aa)
BGLY_3092Zn-dependent hydrolase. (470 aa)
ytbEAldo/keto reductase. (281 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (518 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
ytsJPutative NAD-dependent malic enzyme 4. (411 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
ytcIAMP-dependent synthetase/ligase. (529 aa)
acsAAcetyl-coenzyme A synthetase. (572 aa)
malSMalate dehydrogenase. (565 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (527 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
yvgNGlyoxal reductase. (281 aa)
yvcT2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
maeAPutative NAD-dependent malic enzyme 2. (567 aa)
mmgAacetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ptaPhosphate acetyltransferase. (323 aa)
BGLY_4456Glyoxylase. (149 aa)
mleAMalolactic enzyme. (439 aa)
BGLY_4600Malate synthase; Belongs to the malate synthase family. (529 aa)
BGLY_4675Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (867 aa)
Your Current Organism:
Bacillus glycinifermentans
NCBI taxonomy Id: 1664069
Other names: B. glycinifermentans, Bacillus glycinifermentans Kim et al. 2015, Bacillus sp. GO-13, Bacillus sp. KJ-17, KACC 18425, NRRL B-65291, strain GO-13
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