STRINGSTRING
AB675_9985 AB675_9985 COQ6 COQ6 AB675_3214 AB675_3214 AB675_9759 AB675_9759 COQ4 COQ4 AB675_881 AB675_881 COQ7 COQ7 AB675_2684 AB675_2684 AB675_6536 AB675_6536 AB675_1439 AB675_1439 AB675_3655 AB675_3655 COQ5 COQ5 AB675_2117 AB675_2117
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AB675_9985Methyltransf_25 domain-containing protein. (256 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (507 aa)
AB675_32144-hydroxybenzoate polyprenyltransferase, mitochondrial. (358 aa)
AB675_9759Methyltranfer_dom domain-containing protein. (281 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (303 aa)
AB675_881NAD(P)-bd_dom domain-containing protein. (296 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (272 aa)
AB675_2684Ubiquinone biosynthesis O-methyltransferase, mitochondrial. (230 aa)
AB675_6536ABC1 family protein mitochondrial. (609 aa)
AB675_1439Atypical kinase COQ8, mitochondrial. (780 aa)
AB675_3655ABC1 family protein MCP2. (460 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (304 aa)
AB675_2117Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (248 aa)
Your Current Organism:
Phialophora attae
NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014
Server load: low (32%) [HD]