(10 nodes) Tryptophan catabolic process, and Kynurenine aminotransferase activity network (Phialophora attae)

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Your Input:
	AB675_8950	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (401 aa)
	AB675_2181	Uncharacterized protein. (187 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (496 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (489 aa)
	AB675_6613	FAD_binding_3 domain-containing protein. (445 aa)
	AB675_2468	Indoleamine 2,3-dioxygenase. (465 aa)
	AB675_1102	FAD_binding_3 domain-containing protein. (443 aa)
	AB675_10743	Putative aminotransferase. (398 aa)
	AB675_242	6-hydroxynicotinate 3-monooxygenase. (426 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (472 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10743	AB675_2468	A0A0N1HUQ2	A0A0N1HH50	Putative aminotransferase.	Indoleamine 2,3-dioxygenase.	0.558
AB675_10743	AB675_8950	A0A0N1HUQ2	A0A0N0NIT5	Putative aminotransferase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.786
AB675_10743	BNA4	A0A0N1HUQ2	A0A0N1P3N0	Putative aminotransferase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.831
AB675_10743	BNA5	A0A0N1HUQ2	A0A0N0NRM5	Putative aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.761
AB675_10743	BNA5-2	A0A0N1HUQ2	A0A0N1HAN4	Putative aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.761
AB675_1102	AB675_2181	A0A0N1HR55	A0A0N0NPK6	FAD_binding_3 domain-containing protein.	Uncharacterized protein.	0.457
AB675_1102	BNA5	A0A0N1HR55	A0A0N0NRM5	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.534
AB675_1102	BNA5-2	A0A0N1HR55	A0A0N1HAN4	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.534
AB675_2181	AB675_1102	A0A0N0NPK6	A0A0N1HR55	Uncharacterized protein.	FAD_binding_3 domain-containing protein.	0.457
AB675_2181	AB675_242	A0A0N0NPK6	A0A0N1P2Q5	Uncharacterized protein.	6-hydroxynicotinate 3-monooxygenase.	0.457
AB675_2181	AB675_6613	A0A0N0NPK6	A0A0N1HEW2	Uncharacterized protein.	FAD_binding_3 domain-containing protein.	0.457
AB675_2181	BNA4	A0A0N0NPK6	A0A0N1P3N0	Uncharacterized protein.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.457
AB675_2181	BNA5	A0A0N0NPK6	A0A0N0NRM5	Uncharacterized protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.972
AB675_2181	BNA5-2	A0A0N0NPK6	A0A0N1HAN4	Uncharacterized protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.972
AB675_242	AB675_2181	A0A0N1P2Q5	A0A0N0NPK6	6-hydroxynicotinate 3-monooxygenase.	Uncharacterized protein.	0.457
AB675_242	BNA5	A0A0N1P2Q5	A0A0N0NRM5	6-hydroxynicotinate 3-monooxygenase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.534
AB675_242	BNA5-2	A0A0N1P2Q5	A0A0N1HAN4	6-hydroxynicotinate 3-monooxygenase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.534
AB675_2468	AB675_10743	A0A0N1HH50	A0A0N1HUQ2	Indoleamine 2,3-dioxygenase.	Putative aminotransferase.	0.558
AB675_2468	AB675_8950	A0A0N1HH50	A0A0N0NIT5	Indoleamine 2,3-dioxygenase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.796
AB675_2468	BNA5	A0A0N1HH50	A0A0N0NRM5	Indoleamine 2,3-dioxygenase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.673