(73 nodes) Fungal-type vacuole membrane network (Phialophora attae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AB675_5046	Equilibrative nucleoside transporter 1. (146 aa)
	AB675_2738	Uncharacterized protein. (788 aa)
	AB675_6197	Vacuolar transporter chaperone 1. (72 aa)
	AB675_5475	Uncharacterized protein. (277 aa)
	AB675_2292	Vacuolar cation/proton exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (493 aa)
	AB675_2624	Putative transporter MCH4. (416 aa)
	AB675_9850	Putative vacuolar amino acid transporter YPQ3. (370 aa)
	AB675_5675	V-type proton ATPase catalytic subunit A. (636 aa)
	AB675_4281	Putative Ras-related protein Rab7. (204 aa)
	AB675_10684	Phosphatidylinositol 4-kinase lsb6. (791 aa)
	AB675_8040	Uncharacterized protein. (128 aa)
	AB675_1062	Vacuolar protein 8. (548 aa)
	AB675_164	Vacuolar amino acid transporter 1. (661 aa)
	AB675_3448	CFEM domain-containing protein. (450 aa)
	AB675_3899	Alkaline phosphatase. (627 aa)
	AB675_11526	Niemann-Pick type C-related protein 1. (1276 aa)
	AB675_3192	Alkaline phosphatase. (537 aa)
	AB675_4641	Polyphosphoinositide phosphatase. (1084 aa)
	AB675_9626	Riboflavin transporter MCH5. (421 aa)
	AB675_5677	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (779 aa)
	AB675_6499	Putative oxido YfjR. (305 aa)
	AB675_11630	Vacuolar morphogenesis protein 6. (987 aa)
	AB675_4761	Vacuolar cation/proton exchanger 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (460 aa)
	AB675_10495	Nitrogen permease regulator-like protein. (708 aa)
	AB675_11068	Vacuolar transporter chaperone 3. (569 aa)
	AB675_10481	Uncharacterized protein. (1257 aa)
	AB675_11952	Uncharacterized protein. (364 aa)
	AB675_11652	Low affinity vacuolar monovalent cation/H(+) antiporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1155 aa)
	AB675_1673	Cutinase transcription factor 1 alpha. (1108 aa)
	AB675_2908	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1448 aa)
	AB675_3625	WD repeat-containing protein mip1. (1461 aa)
	AB675_3983	Vacuolar calcium ion transporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (793 aa)
	AB675_1575	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (296 aa)
	AB675_3926	E3 ubiquitin-protein ligase PIB1. (337 aa)
	AB675_1140	V-type proton ATPase subunit D. (261 aa)
	AB675_4154	E3 ubiquitin-protein ligase PEP5. (977 aa)
	AB675_10841	Calcium channel YVC1. (564 aa)
	AB675_10731	Charged multivesicular body protein 5. (217 aa)
	AB675_10882	Vacuolar amino acid transporter 1. (448 aa)
	AB675_9751	V-type proton ATPase subunit E. (229 aa)
	AB675_6727	Vacuolar amino acid transporter 3. (574 aa)
	AB675_6784	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1206 aa)
	AB675_8674	Nitrogen permease regulator 3. (770 aa)
	AB675_265	1-phosphatidylinositol 3-phosphate 5-kinase fab1. (2353 aa)
	AB675_9445	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (464 aa)
	AB675_6092	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (693 aa)
	AB675_5728	Uncharacterized protein. (853 aa)
	AB675_4597	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
	AB675_11263	Riboflavin transporter MCH5. (402 aa)
	AB675_1624	Glyoxylate/succinic semialdehyde 1. (332 aa)
	AB675_8893	Zinc/cadmium resistance protein. (549 aa)
	AB675_10020	Ubiquitin-conjugating enzyme spm2. (139 aa)
	AB675_7889	Vacuolar calcium ion transporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (559 aa)
	AB675_8036	Alpha-mannosidase. (1084 aa)
	AB675_9036	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	AB675_3056	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (861 aa)
	AB675_9225	Vacuolar protein sorting-associated protein 68. (165 aa)
	AB675_5047	Nucleoside transporter FUN26. (291 aa)
	AB675_11364	Putative transporter MCH4. (433 aa)
	AB675_8275	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
	AB675_5209	Zinc-regulated transporter 3. (451 aa)
	AB675_9315	Putative RWD, RING finger and WD repeat-containing protein. (1135 aa)
	AB675_5691	Ras-related GTP-binding protein A. (329 aa)
	AB675_6605	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1282 aa)
	AB675_6634	Riboflavin transporter MCH5. (479 aa)
	AB675_6336	Uncharacterized protein. (387 aa)
	AB675_6465	Vacuolar calcium ion transporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (571 aa)
	AB675_6644	Transforming growth factor-beta receptor-associated protein 1. (1199 aa)
	AB675_6271	GTP-binding protein gtr2. (342 aa)
	AB675_8804	Ras-related C3 botulinum toxin substrate 1. (199 aa)
	AB675_2365	Putative leucine-rich repeat-containing protein. (773 aa)
	AB675_1633	Putative vacuolar amino acid transporter YPQ1. (435 aa)
	AB675_3616	Uncharacterized protein. (1061 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10020	AB675_2365	A0A0N1H515	A0A0N1HGG3	Ubiquitin-conjugating enzyme spm2.	Putative leucine-rich repeat-containing protein.	0.466
AB675_10020	AB675_9036	A0A0N1H515	A0A0N1H640	Ubiquitin-conjugating enzyme spm2.	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family.	0.999
AB675_10481	AB675_11630	A0A0N1NYE0	A0A0N1NVG2	Uncharacterized protein.	Vacuolar morphogenesis protein 6.	0.997
AB675_10481	AB675_4154	A0A0N1NYE0	A0A0N0NKX1	Uncharacterized protein.	E3 ubiquitin-protein ligase PEP5.	0.997
AB675_10481	AB675_4281	A0A0N1NYE0	A0A0N1NZM7	Uncharacterized protein.	Putative Ras-related protein Rab7.	0.969
AB675_10481	AB675_6644	A0A0N1NYE0	A0A0N1HFE2	Uncharacterized protein.	Transforming growth factor-beta receptor-associated protein 1.	0.995
AB675_10495	AB675_3056	A0A0N1NWN2	A0A0N1H6I1	Nitrogen permease regulator-like protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.592
AB675_10495	AB675_3625	A0A0N1NWN2	A0A0N0NJJ1	Nitrogen permease regulator-like protein.	WD repeat-containing protein mip1.	0.784
AB675_10495	AB675_5691	A0A0N1NWN2	A0A0N1HCM4	Nitrogen permease regulator-like protein.	Ras-related GTP-binding protein A.	0.989
AB675_10495	AB675_6271	A0A0N1NWN2	A0A0N1HFF5	Nitrogen permease regulator-like protein.	GTP-binding protein gtr2.	0.950
AB675_10495	AB675_8674	A0A0N1NWN2	A0A0N0NQT2	Nitrogen permease regulator-like protein.	Nitrogen permease regulator 3.	0.997
AB675_10495	AB675_9315	A0A0N1NWN2	A0A0N1HBI5	Nitrogen permease regulator-like protein.	Putative RWD, RING finger and WD repeat-containing protein.	0.997
AB675_1062	AB675_4281	A0A0N1NZ75	A0A0N1NZM7	Vacuolar protein 8.	Putative Ras-related protein Rab7.	0.408
AB675_10684	AB675_265	A0A0N1NZB5	A0A0N0NRZ8	Phosphatidylinositol 4-kinase lsb6.	1-phosphatidylinositol 3-phosphate 5-kinase fab1.	0.829
AB675_10731	AB675_2365	A0A0N0NMU0	A0A0N1HGG3	Charged multivesicular body protein 5.	Putative leucine-rich repeat-containing protein.	0.445
AB675_10882	AB675_5691	A0A0N0NN07	A0A0N1HCM4	Vacuolar amino acid transporter 1.	Ras-related GTP-binding protein A.	0.497
AB675_10882	AB675_6271	A0A0N0NN07	A0A0N1HFF5	Vacuolar amino acid transporter 1.	GTP-binding protein gtr2.	0.536
AB675_11068	AB675_6197	A0A0N1NXH4	A0A0N1P3E4	Vacuolar transporter chaperone 3.	Vacuolar transporter chaperone 1.	0.801
AB675_1140	AB675_1624	A0A0N0NKI6	A0A0N1H4C2	V-type proton ATPase subunit D.	Glyoxylate/succinic semialdehyde 1.	0.634
AB675_1140	AB675_1673	A0A0N0NKI6	A0A0N0NJ18	V-type proton ATPase subunit D.	Cutinase transcription factor 1 alpha.	0.634