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| | AB675_7761 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1042 aa) |
| | AB675_7410 | Uncharacterized protein. (265 aa) |
| | AB675_10155 | tRNA-specific adenosine deaminase 1. (288 aa) |
| | AB675_1302 | Tryptophan--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (523 aa) |
| | AB675_2896 | Uncharacterized protein. (501 aa) |
| | AB675_4409 | Methionyl-tRNA formyltransferase, mitochondrial. (410 aa) |
| | AB675_2941 | Uncharacterized protein. (400 aa) |
| | AB675_3612 | Putative asparagine--tRNA ligase, mitochondrial. (1936 aa) |
| | AB675_1589 | Multisite-specific tRNA:(Cytosine-C(5))-methyltransferase trm4a; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (866 aa) |
| | AIM41 | Altered inheritance of mitochondria protein 41. (140 aa) |
| | AB675_10232 | Uncharacterized protein. (322 aa) |
| | AB675_4043 | Methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (657 aa) |
| | AB675_3931 | Exosome complex component SKI6. (260 aa) |
| | NBP35 | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa) |
| | AB675_982 | Secoisolariciresinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (289 aa) |
| | AB675_4216 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (317 aa) |
| | AB675_12009 | tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (307 aa) |
| | AB675_4132 | Alanine--tRNA ligase. (276 aa) |
| | AB675_4212 | Elongator complex protein 4. (409 aa) |
| | AB675_4219 | Ribonuclease P protein subunit. (241 aa) |
| | AB675_5758 | Uncharacterized protein. (279 aa) |
| | AB675_4708 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase. (460 aa) |
| | AB675_4987 | Arginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (621 aa) |
| | AB675_3367 | U6 snRNA-associated Sm-like protein LSm6. (81 aa) |
| | AB675_3477 | Regulator of Ty1 transposition protein 10. (1106 aa) |
| | AB675_11520 | tRNA pseudouridine synthase 1. (571 aa) |
| | AB675_7605 | Uncharacterized protein. (477 aa) |
| | AB675_8152 | Methyltransf_25 domain-containing protein. (306 aa) |
| | AB675_9163 | Serine--tRNA ligase, cytoplasmic. (478 aa) |
| | AB675_9322 | tRNA dimethylallyltransferase, mitochondrial. (489 aa) |
| | AB675_5709 | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (485 aa) |
| | AB675_1972 | Putative tRNA pseudouridine synthase C25B8.05. (632 aa) |
| | AB675_6916 | EKC/KEOPS complex subunit BUD32. (371 aa) |
| | AB675_6716 | Exosome complex component RRP46. (238 aa) |
| | AB675_6431 | Elongator complex protein 1. (317 aa) |
| | AB675_6433 | Elongator complex protein 1. (170 aa) |
| | AB675_6478 | Multisubstrate pseudouridine synthase 7. (738 aa) |
| | AB675_6432 | Elongator complex protein 1. (784 aa) |
| | AB675_8531 | Mitochondrial translation optimization protein 1. (701 aa) |
| | ALA1 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (963 aa) |
| | AB675_2790 | Uncharacterized protein. (220 aa) |
| | AB675_2855 | Putative exonuclease. (671 aa) |
| | AB675_436 | Aspartate--tRNA ligase, mitochondrial. (662 aa) |
| | AB675_676 | Putative methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (242 aa) |
| | AB675_478 | Uncharacterized protein. (145 aa) |
| | AB675_2268 | Isoleucine--tRNA ligase, cytoplasmic. (1958 aa) |
| | CFD1 | Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (320 aa) |
| | AB675_10995 | tRNA (Uracil(54)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (592 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa) |
| | TRM5 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (471 aa) |
| | AB675_6021 | Elongator complex protein 5. (349 aa) |
| | AB675_1016 | Queuosine salvage protein; Involved in salvaging queuosine. (158 aa) |
| | AB675_3820 | Exosome complex component rrp4. (342 aa) |
| | AB675_11950 | Aspartate--tRNA ligase, cytoplasmic. (555 aa) |
| | AB675_1394 | Threonylcarbamoyl-AMP synthase. (467 aa) |
| | AB675_5143 | Arginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (518 aa) |
| | AB675_1347 | tRNA threonylcarbamoyladenosine dehydratase 2. (518 aa) |
| | AB675_11179 | Uncharacterized protein. (438 aa) |
| | AB675_10102 | tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase. (314 aa) |
| | AB675_5970 | Helicase SEN1. (2045 aa) |
| | AB675_3829 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (539 aa) |
| | AB675_218 | Alpha-ketoglutarate-dependent dioxygenase abh1. (321 aa) |
| | AB675_206 | Uncharacterized protein. (508 aa) |
| | AB675_187 | Glutamate--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (593 aa) |
| | AB675_7844 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (741 aa) |
| | AB675_9361 | Thioredoxin domain-containing protein plp1. (214 aa) |
| | AB675_9324 | Elongator complex protein 2. (741 aa) |
| | AB675_3285 | Diphthamide biosynthesis protein 4. (170 aa) |
| | AB675_3515 | Uncharacterized protein. (1142 aa) |
| | AB675_9760 | tRNA wybutosine-synthesizing protein 3. (332 aa) |
| | AB675_9535 | EKC/KEOPS complex subunit; Belongs to the CGI121/TPRKB family. (195 aa) |
| | AB675_1739 | DUF2156 domain-containing protein. (491 aa) |
| | AB675_7074 | Uncharacterized protein. (480 aa) |
| | AB675_6278 | Ribonuclease Z 1. (997 aa) |
| | AB675_9112 | Modification methylase HphIA; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (686 aa) |
| | AB675_2307 | Diphthamide biosynthesis protein 3. (135 aa) |
| | AB675_332 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (344 aa) |
| | AB675_6213 | Exosome complex component RRP40. (287 aa) |
| | AB675_8835 | Leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (910 aa) |
| | AB675_8577 | tRNA (Guanine(9)-N1)-methyltransferase. (501 aa) |
| | AB675_2792 | Valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1093 aa) |
| | AB675_444 | DPBB_1 domain-containing protein. (206 aa) |
| | AB675_291 | CFEM domain-containing protein. (197 aa) |
| | AB675_4005 | Phenylalanine--tRNA ligase alpha subunit. (515 aa) |
| | AB675_3867 | DNA-directed RNA polymerases I and III subunit RPAC2. (134 aa) |
| | AB675_1298 | tRNA acetyltransferase TAN1. (367 aa) |
| | AB675_1017 | Queuosine salvage protein; Involved in salvaging queuosine. (445 aa) |
| | AB675_11786 | Phenylalanine--tRNA ligase beta subunit. (580 aa) |
| | AB675_6044 | Cysteine--tRNA ligase. (774 aa) |
| | AB675_5857 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]. (703 aa) |
| | AB675_7770 | D-aminoacyl-tRNA deacylase. (174 aa) |
| | AB675_8918 | Uncharacterized protein. (441 aa) |
| | AB675_3135 | Uncharacterized protein. (264 aa) |
| | AB675_3463 | 2OG-FeII_Oxy_2 domain-containing protein. (257 aa) |
| | AB675_1022 | tRNA-aminoacylation cofactor arc1. (454 aa) |
| | AB675_11356 | Asparagine--tRNA ligase, cytoplasmic. (267 aa) |
| | AB675_9283 | tRNA (Uracil-O(2)-)-methyltransferase. (634 aa) |
| | AB675_11383 | Lysine--tRNA ligase. (606 aa) |
| | AB675_7466 | N-acetyltransferase domain-containing protein. (695 aa) |
| | AB675_9376 | Ribonucleases P/MRP protein subunit pop1. (1144 aa) |
| | AB675_5213 | Uncharacterized protein. (231 aa) |
| | AB675_4688 | tRNA modification GTPase GTPBP3, mitochondrial. (637 aa) |
| | AB675_11408 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (379 aa) |
| | AB675_9678 | tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit trm61. (485 aa) |
| | AB675_4709 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase. (284 aa) |
| | AB675_8022 | Allergen Asp f 7. (259 aa) |
| | AB675_8053 | Exosome complex exonuclease RRP6. (810 aa) |
| | AB675_7130 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (480 aa) |
| | AB675_5342 | tRNA (Adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6. (606 aa) |
| | AB675_6163 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (572 aa) |
| | AB675_9572 | tRNA-specific adenosine deaminase subunit tad2. (195 aa) |
| | AB675_7908 | tRNA (Guanine(26)-N(2))-dimethyltransferase, mitochondrial; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (762 aa) |
| | AB675_2361 | DNA-directed RNA polymerases I, II, and III subunit RPABC2. (154 aa) |
| | AB675_675 | Putative methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (323 aa) |
| | AB675_8618 | Lysine--tRNA ligase, mitochondrial. (632 aa) |
| | AB675_409 | Tyrosine--tRNA ligase. (620 aa) |
| | AB675_914 | Uncharacterized protein. (240 aa) |
| | TRM8 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (333 aa) |
| | AB675_298 | Exosome complex exonuclease dis3; Belongs to the RNR ribonuclease family. (1004 aa) |
| | AB675_921 | Tyrosine--tRNA ligase. (413 aa) |
| | AB675_3994 | 3-hydroxyacyl-CoA dehydrogenase type-2. (372 aa) |
| | AB675_1436 | tRNA N6-adenosine threonylcarbamoyltransferase. (254 aa) |
| | AB675_8075 | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (448 aa) |
| | AB675_10056 | Uncharacterized protein. (269 aa) |
| | AB675_9114 | RNase_PH domain-containing protein. (393 aa) |
| | NCS2 | Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (407 aa) |
| | AB675_998 | Putative tRNA-splicing endonuclease subunit tsp-5. (498 aa) |
| | AB675_1119 | PPM-type phosphatase domain-containing protein. (579 aa) |
| | AB675_5604 | Putative glutamate--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (470 aa) |
| | AB675_4559 | tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. (370 aa) |
| | URM1 | Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (146 aa) |
| | AB675_9859 | Glycine--tRNA ligase 1, mitochondrial. (656 aa) |
| | AB675_1142 | Putative proline--tRNA ligase C19C7.06. (571 aa) |
| | AB675_1047 | tRNA pseudouridine(32) synthase, mitochondrial. (590 aa) |
| | AB675_4097 | Putative tRNA(Ile)-lysidine synthase. (642 aa) |
| | AB675_6448 | HD_domain domain-containing protein. (232 aa) |
| | AB675_4201 | Putative tRNA pseudouridine synthase 4. (441 aa) |
| | AB675_4229 | Exosome complex component CSL4. (203 aa) |
| | AB675_4606 | Ribonuclease P/MRP protein subunit POP5. (190 aa) |
| | AB675_10773 | Phenylalanine--tRNA ligase, mitochondrial. (532 aa) |
| | AB675_10590 | RNase_PH domain-containing protein. (423 aa) |
| | AB675_10545 | Putative glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (648 aa) |
| | AB675_10681 | Uncharacterized protein. (386 aa) |
| | AB675_11355 | Asparagine--tRNA ligase, cytoplasmic. (245 aa) |
| | AB675_11483 | Exosome complex component rrp45. (297 aa) |
| | AB675_11495 | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (276 aa) |
| | AB675_5591 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (458 aa) |
| | AB675_5391 | Sen15 domain-containing protein. (191 aa) |
| | AB675_8006 | RCC1 repeat-containing protein C10F6.04. (347 aa) |
| | AB675_390 | Isoleucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1058 aa) |
| | AB675_2061 | DNA-directed RNA polymerases I, II, and III subunit RPABC5. (79 aa) |
| | AB675_5664 | tRNA (Guanine(10)-N2)-methyltransferase. (611 aa) |
| | AB675_9742 | Uncharacterized protein. (199 aa) |
| | AB675_7042 | Cysteine desulfurase, mitochondrial. (510 aa) |
| | AB675_6937 | tRNA (Guanine-N(7)-)-methyltransferase non-catalytic subunit trm82. (677 aa) |
| | AB675_7124 | Uncharacterized protein. (138 aa) |
| | AB675_6930 | Leucine--tRNA ligase, cytoplasmic. (1127 aa) |
| | AB675_6430 | ATP-dependent RNA helicase mtr4. (1078 aa) |
| | AB675_6145 | Poly(A) RNA polymerase protein 1. (724 aa) |
| | AB675_2376 | Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1003 aa) |
| | AB675_2772 | Histidine--tRNA ligase, mitochondrial. (508 aa) |
| | AB675_2344 | Uncharacterized protein. (131 aa) |
| | AB675_2471 | mRNA cleavage and polyadenylation specificity factor complex subunit pta1. (765 aa) |
| | AB675_2689 | Aspartate--tRNA ligase, cytoplasmic. (1070 aa) |
| | AB675_1323 | Proline--tRNA ligase. (657 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (81 aa) |
| | AB675_743 | Adenylyltransferase and sulfurtransferase uba4. (573 aa) |
| | AB675_10503 | Serine--tRNA ligase, mitochondrial. (465 aa) |
| | AB675_1684 | tRNA wybutosine-synthesizing protein 4. (1112 aa) |
| | AB675_8914 | tRNA-dihydrouridine(20) synthase [NAD(P)+]. (268 aa) |
| | NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1099 aa) |
