(16 nodes) Tryptophan metabolic process network (Phialophora attae)

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	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (472 aa)
	AB675_8950	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (401 aa)
	AB675_10604	Anthranilate synthase component 1. (699 aa)
	AB675_5427	Anthranilate phosphoribosyltransferase. (433 aa)
	AB675_9821	Indoleamine 2,3-dioxygenase. (414 aa)
	AB675_2181	Uncharacterized protein. (187 aa)
	AB675_7037	Indoleamine 2,3-dioxygenase. (436 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (496 aa)
	AB675_10465	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (759 aa)
	AB675_11840	Tryptophan synthase. (416 aa)
	AB675_10746	Tryptophan synthase. (742 aa)
	AB675_9332	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (489 aa)
	AB675_2565	Glutaryl-CoA dehydrogenase, mitochondrial. (428 aa)
	AB675_2468	Indoleamine 2,3-dioxygenase. (465 aa)
	AB675_5466	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (310 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10465	AB675_10604	A0A0N1GYR9	A0A0N0NMU7	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Anthranilate synthase component 1.	0.999
AB675_10465	AB675_10746	A0A0N1GYR9	A0A0N1H535	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Tryptophan synthase.	0.997
AB675_10465	AB675_11840	A0A0N1GYR9	A0A0N1H480	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Tryptophan synthase.	0.997
AB675_10465	AB675_2181	A0A0N1GYR9	A0A0N0NPK6	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Uncharacterized protein.	0.561
AB675_10465	AB675_5427	A0A0N1GYR9	A0A0N0NNY5	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Anthranilate phosphoribosyltransferase.	0.999
AB675_10465	AB675_9332	A0A0N1GYR9	A0A0N1H685	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.952
AB675_10465	BNA5	A0A0N1GYR9	A0A0N0NRM5	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.621
AB675_10465	BNA5-2	A0A0N1GYR9	A0A0N1HAN4	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.621
AB675_10604	AB675_10465	A0A0N0NMU7	A0A0N1GYR9	Anthranilate synthase component 1.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.999
AB675_10604	AB675_10746	A0A0N0NMU7	A0A0N1H535	Anthranilate synthase component 1.	Tryptophan synthase.	0.985
AB675_10604	AB675_11840	A0A0N0NMU7	A0A0N1H480	Anthranilate synthase component 1.	Tryptophan synthase.	0.985
AB675_10604	AB675_5427	A0A0N0NMU7	A0A0N0NNY5	Anthranilate synthase component 1.	Anthranilate phosphoribosyltransferase.	0.996
AB675_10604	AB675_9332	A0A0N0NMU7	A0A0N1H685	Anthranilate synthase component 1.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.491
AB675_10746	AB675_10465	A0A0N1H535	A0A0N1GYR9	Tryptophan synthase.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.997
AB675_10746	AB675_10604	A0A0N1H535	A0A0N0NMU7	Tryptophan synthase.	Anthranilate synthase component 1.	0.985
AB675_10746	AB675_11840	A0A0N1H535	A0A0N1H480	Tryptophan synthase.	Tryptophan synthase.	0.999
AB675_10746	AB675_2565	A0A0N1H535	A0A0N1HGU5	Tryptophan synthase.	Glutaryl-CoA dehydrogenase, mitochondrial.	0.542
AB675_10746	AB675_5427	A0A0N1H535	A0A0N0NNY5	Tryptophan synthase.	Anthranilate phosphoribosyltransferase.	0.996
AB675_10746	AB675_5466	A0A0N1H535	A0A0N1P093	Tryptophan synthase.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.405
AB675_10746	AB675_9332	A0A0N1H535	A0A0N1H685	Tryptophan synthase.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.889