(52 nodes) Extrinsic component of membrane network (Phialophora attae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (272 aa)
	AB675_5980	SVP1-like protein 2. (412 aa)
	AB675_1707	Protein msp1, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (773 aa)
	AB675_1301	PRELI/MSF1 domain-containing protein. (252 aa)
	AB675_2258	Putative GTP-binding protein, mitochondrial. (601 aa)
	AB675_6845	Guanine nucleotide-binding protein alpha-3 subunit. (357 aa)
	AB675_4178	Guanine nucleotide-binding protein alpha-2 subunit. (358 aa)
	AB675_4665	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (156 aa)
	AB675_3616	Uncharacterized protein. (1061 aa)
	AB675_12116	Phosphatidylinositol 3-kinase VPS34. (961 aa)
	AB675_4641	Polyphosphoinositide phosphatase. (1084 aa)
	AB675_9164	GTP-binding protein rhb1. (187 aa)
	AB675_2513	Guanine nucleotide-binding protein subunit gamma. (93 aa)
	AB675_2684	Ubiquinone biosynthesis O-methyltransferase, mitochondrial. (230 aa)
	AB675_2402	Guanine nucleotide-binding protein alpha-16 subunit. (653 aa)
	AB675_786	Uncharacterized protein. (1047 aa)
	AB675_6423	Uncharacterized protein. (251 aa)
	AB675_2541	Uncharacterized protein. (269 aa)
	AB675_10495	Nitrogen permease regulator-like protein. (708 aa)
	AB675_1439	Atypical kinase COQ8, mitochondrial. (780 aa)
	AB675_10086	Chitin synthase export chaperone. (292 aa)
	AB675_5957	Uncharacterized protein. (289 aa)
	AB675_8212	Uncharacterized protein. (452 aa)
	AB675_7530	Autophagy-related protein 11. (1477 aa)
	AB675_8635	Vacuolar protein sorting-associated protein 74. (354 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (304 aa)
	AB675_2738	Uncharacterized protein. (788 aa)
	AB675_9985	Methyltransf_25 domain-containing protein. (256 aa)
	AB675_7734	Uncharacterized protein. (724 aa)
	AB675_10638	Uncharacterized protein. (349 aa)
	AB675_9165	WAPL domain-containing protein. (888 aa)
	AB675_6198	WD repeat-containing protein wat1. (383 aa)
	AB675_6464	Protein MSS51, mitochondrial. (818 aa)
	AB675_8674	Nitrogen permease regulator 3. (770 aa)
	AB675_8490	Phosphatidate cytidylyltransferase, mitochondrial. (524 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (507 aa)
	AB675_504	Tether containing UBX domain for GLUT4. (519 aa)
	AB675_265	1-phosphatidylinositol 3-phosphate 5-kinase fab1. (2353 aa)
	AB675_1697	Serine/threonine-protein kinase VPS15. (1625 aa)
	AB675_7323	Uncharacterized protein. (122 aa)
	AB675_4280	Guanine nucleotide-binding protein subunit beta. (353 aa)
	AB675_5954	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (137 aa)
	AB675_10296	Uncharacterized protein. (76 aa)
	AB675_9759	Methyltranfer_dom domain-containing protein. (281 aa)
	AB675_9764	Erf4 domain-containing protein. (278 aa)
	AB675_3432	Serine/threonine-protein kinase atg1. (979 aa)
	AB675_7055	Guanine nucleotide-binding protein subunit alpha. (335 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (303 aa)
	AB675_7632	Regulator of V-ATPase in vacuolar membrane protein 1. (931 aa)
	AB675_10577	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3144 aa)
	AB675_5358	Glucose-induced degradation-like protein. (337 aa)
	AB675_1897	Putative hexaprenyl pyrophosphate synthase, mitochondrial. (742 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10086	AB675_2513	A0A0N1NY71	A0A0N1HX29	Chitin synthase export chaperone.	Guanine nucleotide-binding protein subunit gamma.	0.737
AB675_10086	AB675_4280	A0A0N1NY71	A0A0N1H1Z9	Chitin synthase export chaperone.	Guanine nucleotide-binding protein subunit beta.	0.890
AB675_10086	AB675_786	A0A0N1NY71	A0A0N1HXR8	Chitin synthase export chaperone.	Uncharacterized protein.	0.497
AB675_10086	AB675_9164	A0A0N1NY71	A0A0N1HSB4	Chitin synthase export chaperone.	GTP-binding protein rhb1.	0.512
AB675_10086	AB675_9165	A0A0N1NY71	A0A0N0NNK0	Chitin synthase export chaperone.	WAPL domain-containing protein.	0.512
AB675_10495	AB675_6198	A0A0N1NWN2	A0A0N0NQC9	Nitrogen permease regulator-like protein.	WD repeat-containing protein wat1.	0.704
AB675_10495	AB675_8674	A0A0N1NWN2	A0A0N0NQT2	Nitrogen permease regulator-like protein.	Nitrogen permease regulator 3.	0.997
AB675_10495	AB675_9164	A0A0N1NWN2	A0A0N1HSB4	Nitrogen permease regulator-like protein.	GTP-binding protein rhb1.	0.673
AB675_10495	AB675_9165	A0A0N1NWN2	A0A0N0NNK0	Nitrogen permease regulator-like protein.	WAPL domain-containing protein.	0.673
AB675_10638	AB675_8490	A0A0N0NN21	A0A0N0NQZ3	Uncharacterized protein.	Phosphatidate cytidylyltransferase, mitochondrial.	0.505
AB675_12116	AB675_1697	A0A0N1HRG9	A0A0N1GYU8	Phosphatidylinositol 3-kinase VPS34.	Serine/threonine-protein kinase VPS15.	0.999
AB675_12116	AB675_265	A0A0N1HRG9	A0A0N0NRZ8	Phosphatidylinositol 3-kinase VPS34.	1-phosphatidylinositol 3-phosphate 5-kinase fab1.	0.893
AB675_12116	AB675_3432	A0A0N1HRG9	A0A0N1H8T9	Phosphatidylinositol 3-kinase VPS34.	Serine/threonine-protein kinase atg1.	0.992
AB675_12116	AB675_4641	A0A0N1HRG9	A0A0N1HSA0	Phosphatidylinositol 3-kinase VPS34.	Polyphosphoinositide phosphatase.	0.847
AB675_12116	AB675_5980	A0A0N1HRG9	A0A0N0NJG1	Phosphatidylinositol 3-kinase VPS34.	SVP1-like protein 2.	0.445
AB675_12116	AB675_7530	A0A0N1HRG9	A0A0N1P199	Phosphatidylinositol 3-kinase VPS34.	Autophagy-related protein 11.	0.706
AB675_12116	AB675_9164	A0A0N1HRG9	A0A0N1HSB4	Phosphatidylinositol 3-kinase VPS34.	GTP-binding protein rhb1.	0.485
AB675_12116	AB675_9165	A0A0N1HRG9	A0A0N0NNK0	Phosphatidylinositol 3-kinase VPS34.	WAPL domain-containing protein.	0.485
AB675_1439	AB675_1897	A0A0N1NWT1	A0A0N1HD11	Atypical kinase COQ8, mitochondrial.	Putative hexaprenyl pyrophosphate synthase, mitochondrial.	0.523
AB675_1439	AB675_2541	A0A0N1NWT1	A0A0N1I0D8	Atypical kinase COQ8, mitochondrial.	Uncharacterized protein.	0.769