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AB675_1589 AB675_1589 AB675_3477 AB675_3477 AB675_8152 AB675_8152 AB675_8531 AB675_8531 AB675_478 AB675_478 AB675_10995 AB675_10995 TRM5 TRM5 AB675_4559 AB675_4559 AB675_6448 AB675_6448 AB675_5664 AB675_5664 AB675_9742 AB675_9742 AB675_6937 AB675_6937 AB675_10102 AB675_10102 AB675_9760 AB675_9760 AB675_9112 AB675_9112 AB675_332 AB675_332 AB675_8577 AB675_8577 AB675_8918 AB675_8918 AB675_3463 AB675_3463 AB675_9283 AB675_9283 AB675_4688 AB675_4688 AB675_11408 AB675_11408 AB675_9678 AB675_9678 AB675_5342 AB675_5342 AB675_7908 AB675_7908 AB675_914 AB675_914 TRM8 TRM8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AB675_1589Multisite-specific tRNA:(Cytosine-C(5))-methyltransferase trm4a; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (866 aa)
AB675_3477Regulator of Ty1 transposition protein 10. (1106 aa)
AB675_8152Methyltransf_25 domain-containing protein. (306 aa)
AB675_8531Mitochondrial translation optimization protein 1. (701 aa)
AB675_478Uncharacterized protein. (145 aa)
AB675_10995tRNA (Uracil(54)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (592 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (471 aa)
AB675_4559tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. (370 aa)
AB675_6448HD_domain domain-containing protein. (232 aa)
AB675_5664tRNA (Guanine(10)-N2)-methyltransferase. (611 aa)
AB675_9742Uncharacterized protein. (199 aa)
AB675_6937tRNA (Guanine-N(7)-)-methyltransferase non-catalytic subunit trm82. (677 aa)
AB675_10102tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase. (314 aa)
AB675_9760tRNA wybutosine-synthesizing protein 3. (332 aa)
AB675_9112Modification methylase HphIA; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (686 aa)
AB675_332Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (344 aa)
AB675_8577tRNA (Guanine(9)-N1)-methyltransferase. (501 aa)
AB675_8918Uncharacterized protein. (441 aa)
AB675_34632OG-FeII_Oxy_2 domain-containing protein. (257 aa)
AB675_9283tRNA (Uracil-O(2)-)-methyltransferase. (634 aa)
AB675_4688tRNA modification GTPase GTPBP3, mitochondrial. (637 aa)
AB675_11408Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (379 aa)
AB675_9678tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit trm61. (485 aa)
AB675_5342tRNA (Adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6. (606 aa)
AB675_7908tRNA (Guanine(26)-N(2))-dimethyltransferase, mitochondrial; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (762 aa)
AB675_914Uncharacterized protein. (240 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (333 aa)
Your Current Organism:
Phialophora attae
NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014
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