(54 nodes) Cellular ketone metabolic process network (Phialophora attae)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (304 aa)
	AB675_2117	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (248 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (303 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (489 aa)
	AB675_1897	Putative hexaprenyl pyrophosphate synthase, mitochondrial. (742 aa)
	AB675_1930	NADH-ubiquinone oxido 40 kDa subunit, mitochondrial. (305 aa)
	AB675_2461	Uncharacterized protein. (312 aa)
	AB675_1417	Uncharacterized protein. (264 aa)
	AB675_2468	Indoleamine 2,3-dioxygenase. (465 aa)
	AB675_881	NAD(P)-bd_dom domain-containing protein. (296 aa)
	AB675_3303	Lactoylglutathione lyase. (237 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (272 aa)
	AB675_10743	Putative aminotransferase. (398 aa)
	AB675_8653	15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (288 aa)
	AB675_2684	Ubiquinone biosynthesis O-methyltransferase, mitochondrial. (230 aa)
	AB675_2541	Uncharacterized protein. (269 aa)
	AB675_11947	Glyoxalase 3. (304 aa)
	AB675_1439	Atypical kinase COQ8, mitochondrial. (780 aa)
	AB675_11049	Nitronate monooxygenase. (360 aa)
	AB675_3154	DJ-1_PfpI domain-containing protein. (287 aa)
	AB675_5227	AP-1-like transcription factor. (626 aa)
	AB675_7548	Uncharacterized protein. (860 aa)
	AB675_5160	15-hydroxyprostaglandin dehydrogenase [NAD(+)]. (240 aa)
	AB675_11574	Uncharacterized protein. (119 aa)
	AB675_7542	Salutaridine; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
	AB675_764	Polyketide_cyc domain-containing protein. (118 aa)
	AB675_8950	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (401 aa)
	AB675_7352	Diacetyl [(S)-acetoin forming]. (280 aa)
	AB675_10081	3-oxosteroid 1-dehydrogenase. (606 aa)
	AB675_9985	Methyltransf_25 domain-containing protein. (256 aa)
	AB675_1590	Putative oxido SadH. (282 aa)
	AB675_3144	Uncharacterized protein. (510 aa)
	AB675_982	Secoisolariciresinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (289 aa)
	AB675_3487	Alpha-acetolactate decarboxylase. (240 aa)
	AB675_11607	Lactoylglutathione lyase. (319 aa)
	AB675_7792	15-hydroxyprostaglandin dehydrogenase [NAD(+)]. (260 aa)
	AB675_5399	DJ-1_PfpI domain-containing protein. (297 aa)
	AB675_9494	Uncharacterized protein. (224 aa)
	AB675_11898	NAD/NADP-dependent indole-3-acetaldehyde. (296 aa)
	AB675_9821	Indoleamine 2,3-dioxygenase. (414 aa)
	AB675_3994	3-hydroxyacyl-CoA dehydrogenase type-2. (372 aa)
	AB675_2939	NADPH:adrenodoxin oxidoreductase, mitochondrial. (485 aa)
	AB675_5245	Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase. (393 aa)
	AB675_3214	4-hydroxybenzoate polyprenyltransferase, mitochondrial. (358 aa)
	AB675_11695	2Fe-2S ferredoxin-type domain-containing protein. (201 aa)
	AB675_2277	Capreomycidine synthase. (365 aa)
	AB675_9927	Nitronate monooxygenase. (336 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (496 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (507 aa)
	AB675_7037	Indoleamine 2,3-dioxygenase. (436 aa)
	AB675_2181	Uncharacterized protein. (187 aa)
	AB675_4897	Nitronate monooxygenase. (354 aa)
	AB675_6081	Carbonyl [NADPH] 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (287 aa)
	AB675_9759	Methyltranfer_dom domain-containing protein. (281 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10081	AB675_10743	A0A0N0NJ72	A0A0N1HUQ2	3-oxosteroid 1-dehydrogenase.	Putative aminotransferase.	0.472
AB675_10081	AB675_11695	A0A0N0NJ72	A0A0N1GXZ2	3-oxosteroid 1-dehydrogenase.	2Fe-2S ferredoxin-type domain-containing protein.	0.624
AB675_10081	AB675_2277	A0A0N0NJ72	A0A0N1GXE4	3-oxosteroid 1-dehydrogenase.	Capreomycidine synthase.	0.472
AB675_10743	AB675_10081	A0A0N1HUQ2	A0A0N0NJ72	Putative aminotransferase.	3-oxosteroid 1-dehydrogenase.	0.472
AB675_10743	AB675_11574	A0A0N1HUQ2	A0A0N1P0A9	Putative aminotransferase.	Uncharacterized protein.	0.425
AB675_10743	AB675_11607	A0A0N1HUQ2	A0A0N0NM40	Putative aminotransferase.	Lactoylglutathione lyase.	0.425
AB675_10743	AB675_2468	A0A0N1HUQ2	A0A0N1HH50	Putative aminotransferase.	Indoleamine 2,3-dioxygenase.	0.558
AB675_10743	AB675_2939	A0A0N1HUQ2	A0A0N1H3T5	Putative aminotransferase.	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.557
AB675_10743	AB675_3303	A0A0N1HUQ2	A0A0N1HPB4	Putative aminotransferase.	Lactoylglutathione lyase.	0.425
AB675_10743	AB675_7037	A0A0N1HUQ2	A0A0N0NQ66	Putative aminotransferase.	Indoleamine 2,3-dioxygenase.	0.558
AB675_10743	AB675_8950	A0A0N1HUQ2	A0A0N0NIT5	Putative aminotransferase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.786
AB675_10743	AB675_9821	A0A0N1HUQ2	A0A0N0NPD3	Putative aminotransferase.	Indoleamine 2,3-dioxygenase.	0.557
AB675_10743	BNA5	A0A0N1HUQ2	A0A0N0NRM5	Putative aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.761
AB675_10743	BNA5-2	A0A0N1HUQ2	A0A0N1HAN4	Putative aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.761
AB675_11049	AB675_4897	A0A0N1NXK7	A0A0N0NHK0	Nitronate monooxygenase.	Nitronate monooxygenase.	0.539
AB675_11574	AB675_10743	A0A0N1P0A9	A0A0N1HUQ2	Uncharacterized protein.	Putative aminotransferase.	0.425
AB675_11574	AB675_11607	A0A0N1P0A9	A0A0N0NM40	Uncharacterized protein.	Lactoylglutathione lyase.	0.743
AB675_11574	AB675_11695	A0A0N1P0A9	A0A0N1GXZ2	Uncharacterized protein.	2Fe-2S ferredoxin-type domain-containing protein.	0.697
AB675_11574	AB675_11947	A0A0N1P0A9	A0A0N1NWB7	Uncharacterized protein.	Glyoxalase 3.	0.687
AB675_11574	AB675_2277	A0A0N1P0A9	A0A0N1GXE4	Uncharacterized protein.	Capreomycidine synthase.	0.425