(114 nodes) Endosome network (Phialophora attae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AB675_11119	Charged multivesicular body protein 6. (214 aa)
	AB675_4076	3'(2'),5'-bisphosphate nucleotidase. (357 aa)
	AB675_3847	Vacuolar protein sorting-associated protein 4; Belongs to the AAA ATPase family. (450 aa)
	AB675_1281	Ras-related protein Rab-11B. (212 aa)
	AB675_2416	Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1473 aa)
	AB675_2479	Uncharacterized protein. (387 aa)
	AB675_2245	Putative membrane protein. (552 aa)
	AB675_826	Mono-and diacylglycerol lipase. (365 aa)
	AB675_10931	Chloride channel protein. (849 aa)
	AB675_1099	Aldo-keto yakc [NADP(+)]. (357 aa)
	AB675_4257	Putative arrestin-related trafficking adapter C2D10.04. (706 aa)
	AB675_7322	Aldo-keto yakc [NADP(+)]. (320 aa)
	AB675_5236	Uncharacterized protein. (146 aa)
	AB675_11454	Vacuolar fusion protein MON1. (581 aa)
	AB675_3977	Putative lipase ATG15. (417 aa)
	AB675_11415	Ubiquitin carboxyl-terminal hydrolase 5. (1062 aa)
	AB675_7897	Protein SSH4. (464 aa)
	AB675_8211	Vacuolar protein-sorting protein bro1. (430 aa)
	AB675_6443	Uncharacterized protein. (1225 aa)
	AB675_6505	Sorting nexin-3. (104 aa)
	AB675_5677	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (779 aa)
	AB675_8628	Dihydroxy-acid dehydratase. (619 aa)
	AB675_942	Chloride channel protein. (856 aa)
	AB675_8363	Vacuolar protein sorting-associated protein 21. (249 aa)
	AB675_2743	Palmitoyltransferase akr1. (406 aa)
	AB675_10152	Putative mannose 6-phosphate receptor-like protein. (335 aa)
	AB675_4938	Uncharacterized protein. (600 aa)
	AB675_11999	Uncharacterized protein; Belongs to the synaptobrevin family. (249 aa)
	AB675_7351	Uncharacterized protein. (495 aa)
	AB675_5122	Uncharacterized protein. (261 aa)
	AB675_4339	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (263 aa)
	AB675_9224	Vacuolar protein sorting-associated protein 55. (133 aa)
	AB675_2065	Deubiquitination-protection protein dph1. (444 aa)
	AB675_7059	Uncharacterized protein. (524 aa)
	AB675_7151	pH-response regulator protein palC. (476 aa)
	AB675_8054	Vacuolar-sorting protein SNF7. (220 aa)
	AB675_8210	Vacuolar protein-sorting protein bro1. (537 aa)
	AB675_2763	PX domain-containing protein YPT35. (190 aa)
	AB675_8538	TBC1 domain family member 5. (736 aa)
	AB675_2871	Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family. (628 aa)
	AB675_949	Uncharacterized protein. (182 aa)
	AB675_2749	Actin cytoskeleton-regulatory complex protein sla1. (1126 aa)
	AB675_1465	Uncharacterized protein. (811 aa)
	AB675_3926	E3 ubiquitin-protein ligase PIB1. (337 aa)
	AB675_4290	Phospholipase. (1238 aa)
	AB675_4154	E3 ubiquitin-protein ligase PEP5. (977 aa)
	AB675_4269	N-acetyltransferase domain-containing protein. (235 aa)
	AB675_4088	Uncharacterized protein. (493 aa)
	AB675_4461	Mono-and diacylglycerol lipase. (191 aa)
	AB675_5137	Uncharacterized protein. (191 aa)
	AB675_5118	Uncharacterized protein. (699 aa)
	AB675_3477	Regulator of Ty1 transposition protein 10. (1106 aa)
	AB675_11510	Heavy metal tolerance protein. (821 aa)
	AB675_11414	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (661 aa)
	AB675_10544	Vacuolar segregation protein PEP7. (698 aa)
	AB675_10731	Charged multivesicular body protein 5. (217 aa)
	AB675_9363	Beige-like protein. (894 aa)
	AB675_9364	Beige-like protein. (2022 aa)
	AB675_9594	Putative oxido C1F5.03c. (434 aa)
	AB675_7137	Putative membrane protein. (553 aa)
	AB675_6547	Vacuolar protein-sorting-associated protein 46. (206 aa)
	AB675_6182	Vacuolar protein-sorting-associated protein 25. (205 aa)
	AB675_6353	pH-response regulator protein palA/RIM20. (848 aa)
	AB675_2742	Palmitoyltransferase akr1. (233 aa)
	AB675_366	GTP-binding protein ypt5. (217 aa)
	AB675_11047	Putative membrane protein. (646 aa)
	AB675_10204	H(+)/Cl(-) exchange transporter 3. (762 aa)
	AB675_7201	Chloride channel protein. (835 aa)
	AB675_8916	Calpain-like protease palB/RIM13; Belongs to the peptidase C2 family. (864 aa)
	AB675_10019	Uncharacterized protein. (1689 aa)
	AB675_6089	BAR domain-containing protein. (388 aa)
	AB675_5981	Type I inositol 1,4,5-trisphosphate 5-phosphatase 2. (1146 aa)
	AB675_6092	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (693 aa)
	AB675_12002	Vacuolar protein sorting-associated protein 24. (229 aa)
	AB675_4243	Uncharacterized protein. (124 aa)
	AB675_4116	Putative membrane protein. (1190 aa)
	AB675_4150	Radical_SAM domain-containing protein. (380 aa)
	AB675_5241	Class E vacuolar protein-sorting machinery protein hse1. (609 aa)
	AB675_2892	Dihydroxy-acid dehydratase. (599 aa)
	AB675_10093	Trafficking protein particle complex subunit 10. (1407 aa)
	AB675_4777	Sorting nexin-4. (492 aa)
	AB675_10804	Vesicle transport v-SNARE protein vti1. (198 aa)
	AB675_10751	Protein transport protein BOS1. (499 aa)
	AB675_11791	PXA domain-containing protein. (668 aa)
	AB675_3948	Ran-binding protein 9. (667 aa)
	AB675_7932	Heavy metal tolerance protein. (934 aa)
	AB675_8012	Putative lipase ATG15. (649 aa)
	AB675_1029	DUF1308 domain-containing protein. (608 aa)
	AB675_9225	Vacuolar protein sorting-associated protein 68. (165 aa)
	AB675_4151	Transmembrane protein 19. (343 aa)
	AB675_5893	Uncharacterized protein. (903 aa)
	URM1	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (146 aa)
	AB675_1105	Aldo-keto yakc [NADP(+)]. (303 aa)
	AB675_1820	Putative membrane protein. (527 aa)
	AB675_5121	Zinc transporter ZIP9. (142 aa)
	AB675_7091	Cystinosin-like protein. (242 aa)
	AB675_7483	CRAL-TRIO domain-containing protein C3H8.02. (799 aa)
	AB675_10878	Phospholipase D1. (828 aa)
	AB675_7456	Vacuolar protein sorting-associated protein IST1. (327 aa)
	AB675_10577	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3144 aa)
	AB675_2546	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (702 aa)
	AB675_962	Putative peptide/nitrate transporter. (502 aa)
	AB675_5521	Uncharacterized protein. (189 aa)
	AB675_9624	Putative magnesium transporter NIPA8. (559 aa)
	AB675_9378	Transport protein particle subunit. (1298 aa)
	AB675_5393	Aldo-keto yakc [NADP(+)]. (307 aa)
	AB675_5494	Uncharacterized protein. (318 aa)
	AB675_5653	Aldo-keto yakc [NADP(+)]. (326 aa)
	AB675_9826	Putative membrane protein. (565 aa)
	AB675_9726	Uncharacterized protein. (268 aa)
	AB675_2192	Protein AFG1. (547 aa)
	AB675_2083	Vacuolar protein-sorting-associated protein 36. (964 aa)
	AB675_6350	VPS37 C-terminal domain-containing protein. (311 aa)
	AB675_6644	Transforming growth factor-beta receptor-associated protein 1. (1199 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10019	AB675_6505	A0A0N1GZU6	A0A0N1HVM0	Uncharacterized protein.	Sorting nexin-3.	0.443
AB675_10093	AB675_1281	A0A0N1H446	A0A0N0NIG2	Trafficking protein particle complex subunit 10.	Ras-related protein Rab-11B.	0.835
AB675_10093	AB675_4938	A0A0N1H446	A0A0N1NX57	Trafficking protein particle complex subunit 10.	Uncharacterized protein.	0.968
AB675_10093	AB675_9378	A0A0N1H446	A0A0N1HCD7	Trafficking protein particle complex subunit 10.	Transport protein particle subunit.	0.999
AB675_10152	AB675_10804	A0A0N1NWF4	A0A0N1H518	Putative mannose 6-phosphate receptor-like protein.	Vesicle transport v-SNARE protein vti1.	0.706
AB675_10152	AB675_1281	A0A0N1NWF4	A0A0N0NIG2	Putative mannose 6-phosphate receptor-like protein.	Ras-related protein Rab-11B.	0.425
AB675_10152	AB675_2065	A0A0N1NWF4	A0A0N1P044	Putative mannose 6-phosphate receptor-like protein.	Deubiquitination-protection protein dph1.	0.592
AB675_10152	AB675_2416	A0A0N1NWF4	A0A0N1HG53	Putative mannose 6-phosphate receptor-like protein.	Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.	0.792
AB675_10152	AB675_2546	A0A0N1NWF4	A0A0N1HB14	Putative mannose 6-phosphate receptor-like protein.	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.499
AB675_10152	AB675_2763	A0A0N1NWF4	A0A0N1P1S7	Putative mannose 6-phosphate receptor-like protein.	PX domain-containing protein YPT35.	0.642
AB675_10152	AB675_366	A0A0N1NWF4	A0A0N0NS17	Putative mannose 6-phosphate receptor-like protein.	GTP-binding protein ypt5.	0.594
AB675_10152	AB675_4777	A0A0N1NWF4	A0A0N1H4I9	Putative mannose 6-phosphate receptor-like protein.	Sorting nexin-4.	0.642
AB675_10152	AB675_5118	A0A0N1NWF4	A0A0N0NLR0	Putative mannose 6-phosphate receptor-like protein.	Uncharacterized protein.	0.642
AB675_10152	AB675_5677	A0A0N1NWF4	A0A0N1HWI7	Putative mannose 6-phosphate receptor-like protein.	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.499
AB675_10152	AB675_8363	A0A0N1NWF4	A0A0N1HZH3	Putative mannose 6-phosphate receptor-like protein.	Vacuolar protein sorting-associated protein 21.	0.594
AB675_10204	AB675_942	A0A0N1GXC4	A0A0N1HXT1	H(+)/Cl(-) exchange transporter 3.	Chloride channel protein.	0.508
AB675_10544	AB675_11414	A0A0N0NMM7	A0A0N0NM98	Vacuolar segregation protein PEP7.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.495
AB675_10544	AB675_1281	A0A0N0NMM7	A0A0N0NIG2	Vacuolar segregation protein PEP7.	Ras-related protein Rab-11B.	0.674
AB675_10544	AB675_2871	A0A0N0NMM7	A0A0N1P2I4	Vacuolar segregation protein PEP7.	Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family.	0.509
AB675_10544	AB675_366	A0A0N0NMM7	A0A0N0NS17	Vacuolar segregation protein PEP7.	GTP-binding protein ypt5.	0.906