(66 nodes) Ubiquinone and other terpenoid-quinone biosynthesis network (Phialophora attae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	AB675_10115	Putative 4-coumarate--CoA ligase 3. (562 aa)
	AB675_6	Putative polyketide hydroxylase. (330 aa)
	AB675_7063	4-coumarate--CoA ligase-like 5. (631 aa)
	AB675_964	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (273 aa)
	AB675_7098	3-dehydroshikimate dehydratase. (345 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (304 aa)
	AB675_6342	3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase. (630 aa)
	AB675_10897	Putative 4-coumarate--CoA ligase 1. (256 aa)
	AB675_11055	4-coumarate--CoA ligase-like 7. (577 aa)
	AB675_3684	Tetracenomycin polyketide synthesis hydroxylase TcmG. (565 aa)
	AB675_2541	Uncharacterized protein. (269 aa)
	AB675_2684	Ubiquinone biosynthesis O-methyltransferase, mitochondrial. (230 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (272 aa)
	AB675_11276	Acyl-coenzyme A thioesterase 13. (153 aa)
	AB675_3566	Para-nitrophenol 4-monooxygenase. (411 aa)
	AB675_208	Putative acyl-coenzyme A synthetase. (563 aa)
	AB675_3827	4-coumarate--CoA ligase-like 7. (553 aa)
	AB675_6195	Uncharacterized protein. (284 aa)
	AB675_6154	2,4-dichlorophenol 6-monooxygenase. (595 aa)
	AB675_9555	Non-heme chloroperoxidase. (276 aa)
	AB675_491	Putative 4-coumarate--CoA ligase 1. (581 aa)
	AB675_7923	Putative acyl-coenzyme A synthetase. (292 aa)
	AB675_2452	Aromatic amino acid aminotransferase. (580 aa)
	AB675_8308	2,4-dichlorophenol 6-monooxygenase. (617 aa)
	AB675_11317	2,4-dichlorophenol 6-monooxygenase. (594 aa)
	AB675_9759	Methyltranfer_dom domain-containing protein. (281 aa)
	AB675_12026	4HBT domain-containing protein. (183 aa)
	AB675_12145	Putative acyl-coenzyme A synthetase. (548 aa)
	AB675_9202	Abhydrolase domain-containing protein IMO32. (313 aa)
	AB675_9392	4-coumarate--CoA ligase-like 7. (580 aa)
	AB675_10788	2,4-dichlorophenol 6-monooxygenase. (579 aa)
	AB675_10522	Putative acyl-coenzyme A synthetase. (544 aa)
	AB675_1232	Para-nitrophenol 4-monooxygenase. (435 aa)
	AB675_1230	Putative acyl-coenzyme A synthetase. (553 aa)
	AB675_4979	Putative 4-coumarate--CoA ligase 1. (550 aa)
	AB675_4818	3-dehydroshikimate dehydratase. (339 aa)
	AB675_3214	4-hydroxybenzoate polyprenyltransferase, mitochondrial. (358 aa)
	AB675_8860	Aromatic amino acid aminotransferase C56E4.03. (651 aa)
	AB675_10463	2,4-dichlorophenol 6-monooxygenase. (581 aa)
	AB675_10143	3-dehydroshikimate dehydratase. (421 aa)
	AB675_437	Capreomycidine synthase. (406 aa)
	AB675_751	4-hydroxyphenylpyruvate dioxygenase. (405 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (507 aa)
	AB675_6543	4-coumarate--CoA ligase-like 2. (581 aa)
	AB675_7125	Putative acyl-CoA synthetase YngI. (573 aa)
	AB675_6765	Putative acyl-coenzyme A synthetase. (573 aa)
	AB675_9853	2,4-dichlorophenol 6-monooxygenase. (606 aa)
	AB675_9824	Para-nitrophenol 4-monooxygenase. (437 aa)
	AB675_5557	Aromatic amino acid aminotransferase C56E4.03. (612 aa)
	AB675_7924	Putative acyl-coenzyme A synthetase. (240 aa)
	AB675_7516	Uncharacterized protein. (1072 aa)
	AB675_7544	Para-nitrophenol 4-monooxygenase. (446 aa)
	AB675_7474	4-coumarate--CoA ligase 2. (543 aa)
	AB675_3408	Para-nitrophenol 4-monooxygenase. (447 aa)
	AB675_5886	Para-nitrophenol 4-monooxygenase. (438 aa)
	AB675_5868	Minor allergen Alt a 7. (267 aa)
	AB675_12022	Putative acyl-coenzyme A synthetase. (560 aa)
	AB675_12114	Putative tocopherol O-methyltransferase, chloroplastic. (401 aa)
	AB675_3902	Para-nitrophenol 4-monooxygenase. (525 aa)
	AB675_10369	4HBT domain-containing protein. (183 aa)
	AB675_9985	Methyltransf_25 domain-containing protein. (256 aa)
	AB675_7353	Putative 4-coumarate--CoA ligase 2. (560 aa)
	AB675_10438	3-dehydroshikimate dehydratase. (344 aa)
	AB675_10442	AB hydrolase-1 domain-containing protein. (287 aa)
	AB675_10994	Putative acyl-coenzyme A synthetase. (546 aa)
	AB675_3	Para-nitrophenol 4-monooxygenase. (414 aa)

Your Current Organism:

Phialophora attae

NCBI taxonomy Id: 1664694
Other names: CBS 131958, P. attae, Phialophora attae Attili-Angelis, Duarte, Stielow & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AB675_10143	AB675_2452	A0A0N1GXQ6	A0A0N1HAJ8	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase.	0.472
AB675_10143	AB675_5557	A0A0N1GXQ6	A0A0N0NP09	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase C56E4.03.	0.472
AB675_10143	AB675_751	A0A0N1GXQ6	A0A0N0NSA0	3-dehydroshikimate dehydratase.	4-hydroxyphenylpyruvate dioxygenase.	0.655
AB675_10143	AB675_8860	A0A0N1GXQ6	A0A0N1GYW5	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase C56E4.03.	0.578
AB675_10369	AB675_12026	A0A0N0NJV8	A0A0N1H6N6	4HBT domain-containing protein.	4HBT domain-containing protein.	0.806
AB675_10438	AB675_2452	A0A0N0NIP1	A0A0N1HAJ8	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase.	0.440
AB675_10438	AB675_5557	A0A0N0NIP1	A0A0N0NP09	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase C56E4.03.	0.440
AB675_10438	AB675_751	A0A0N0NIP1	A0A0N0NSA0	3-dehydroshikimate dehydratase.	4-hydroxyphenylpyruvate dioxygenase.	0.599
AB675_10438	AB675_8860	A0A0N0NIP1	A0A0N1GYW5	3-dehydroshikimate dehydratase.	Aromatic amino acid aminotransferase C56E4.03.	0.440
AB675_10442	AB675_2541	A0A0N0NIM6	A0A0N1I0D8	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.400
AB675_10442	AB675_2684	A0A0N0NIM6	A0A0N1HX56	AB hydrolase-1 domain-containing protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial.	0.400
AB675_10442	AB675_7125	A0A0N0NIM6	A0A0N0NQ88	AB hydrolase-1 domain-containing protein.	Putative acyl-CoA synthetase YngI.	0.423
AB675_10442	AB675_9759	A0A0N0NIM6	A0A0N1H787	AB hydrolase-1 domain-containing protein.	Methyltranfer_dom domain-containing protein.	0.400
AB675_10442	AB675_9985	A0A0N0NIM6	A0A0N0NJI0	AB hydrolase-1 domain-containing protein.	Methyltransf_25 domain-containing protein.	0.400
AB675_10463	AB675_2541	A0A0N1GYQ1	A0A0N1I0D8	2,4-dichlorophenol 6-monooxygenase.	Uncharacterized protein.	0.556
AB675_10463	AB675_2684	A0A0N1GYQ1	A0A0N1HX56	2,4-dichlorophenol 6-monooxygenase.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial.	0.556
AB675_10463	AB675_3214	A0A0N1GYQ1	A0A0N1H1E9	2,4-dichlorophenol 6-monooxygenase.	4-hydroxybenzoate polyprenyltransferase, mitochondrial.	0.478
AB675_10463	AB675_9759	A0A0N1GYQ1	A0A0N1H787	2,4-dichlorophenol 6-monooxygenase.	Methyltranfer_dom domain-containing protein.	0.556
AB675_10463	AB675_9985	A0A0N1GYQ1	A0A0N0NJI0	2,4-dichlorophenol 6-monooxygenase.	Methyltransf_25 domain-containing protein.	0.556
AB675_10463	COQ5	A0A0N1GYQ1	A0A0N1P1T1	2,4-dichlorophenol 6-monooxygenase.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.477