STRINGSTRING
APH70459.1 APH70459.1 APH70304.1 APH70304.1 aroE aroE leuB leuB APH70211.1 APH70211.1 APH70130.1 APH70130.1 APH70110.1 APH70110.1 gpsA gpsA APH69963.1 APH69963.1 mdh mdh APH73883.1 APH73883.1 APH73940.1 APH73940.1 APH74059.1 APH74059.1 APH74732.1 APH74732.1 APH73456.1 APH73456.1 lcdH lcdH guaB guaB hisD hisD zwf zwf APH72394.1 APH72394.1 APH72289.1 APH72289.1 APH72159.1 APH72159.1 APH72113.1 APH72113.1 APH72050.1 APH72050.1 APH71917.1 APH71917.1 APH71817.1 APH71817.1 pdxA pdxA APH74510.1 APH74510.1 APH71584.1 APH71584.1 APH71101.1 APH71101.1 APH70835.1 APH70835.1 APH70781.1 APH70781.1 APH74389.1 APH74389.1 APH70588.1 APH70588.1 APH70481.1 APH70481.1 APH70371.1 APH70371.1 APH73286.1 APH73286.1 tdh tdh APH73188.1 APH73188.1 APH73148.1 APH73148.1 APH72974.1 APH72974.1 APH72928.1 APH72928.1 murB murB ilvC ilvC APH72594.1 APH72594.1 APH72449.1 APH72449.1 APH72427.1 APH72427.1 APH73836.1 APH73836.1 APH74765.1 APH74765.1 APH73775.1 APH73775.1 APH73745.1 APH73745.1 APH73681.1 APH73681.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APH70459.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
APH70304.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)
APH70211.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (282 aa)
APH70130.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
APH70110.1Galactose 1-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (328 aa)
APH69963.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (350 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa)
APH73883.1D-mannonate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (493 aa)
APH73940.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APH74059.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
APH74732.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
APH73456.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (737 aa)
lcdHCarnitine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (358 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
APH72394.1UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (443 aa)
APH72289.1NADP-dependent malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
APH72159.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
APH72113.12,5-didehydrogluconate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
APH72050.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
APH71917.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
APH71817.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (346 aa)
APH74510.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
APH71584.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
APH71101.12-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
APH70835.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
APH70781.12-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
APH74389.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
APH70588.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
APH70481.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
APH70371.1NADP-dependent malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa)
APH73286.1Maleylacetate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (344 aa)
APH73188.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (700 aa)
APH73148.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
APH72974.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (376 aa)
APH72928.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (321 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
APH72594.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (294 aa)
APH72449.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
APH72427.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
APH73836.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
APH74765.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
APH73775.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
APH73745.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
APH73681.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
Your Current Organism:
Mesorhizobium oceanicum
NCBI taxonomy Id: 1670800
Other names: KCTC 42783, M. oceanicum, MCCC 1K02305, Mesorhizobium oceanicum Fu et al. 2017, Mesorhizobium sp. B7, strain B7
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