STRINGSTRING
KMT56606.1 KMT56606.1 KMT52721.1 KMT52721.1 KMT52720.1 KMT52720.1 KMT52719.1 KMT52719.1 KMT52718.1 KMT52718.1 KMT52716.1 KMT52716.1 KMT52715.1 KMT52715.1 KMT52743.1 KMT52743.1 KMT52714.1 KMT52714.1 KMT53321.1 KMT53321.1 hemC hemC KMT53493.1 KMT53493.1 KMT53491.1 KMT53491.1 KMT53473.1 KMT53473.1 cysG cysG KMT54248.1 KMT54248.1 KMT54247.1 KMT54247.1 KMT54245.1 KMT54245.1 KMT54389.1 KMT54389.1 hemL hemL KMT55422.1 KMT55422.1 hemA hemA hemH hemH hemE hemE cyoE-2 cyoE-2 KMT56231.1 KMT56231.1 KMT56012.1 KMT56012.1 KMT56608.1 KMT56608.1 hemF hemF KMT56486.1 KMT56486.1 cyoE cyoE KMT57008.1 KMT57008.1 cobD cobD KMT56765.1 KMT56765.1 KMT56697.1 KMT56697.1 KMT56661.1 KMT56661.1 KMT56659.1 KMT56659.1 KMT57589.1 KMT57589.1 KMT57682.1 KMT57682.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KMT56606.14-hydroxytetrahydrobiopterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
KMT52721.1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
KMT52720.1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (461 aa)
KMT52719.1Cytochrome Cbb3; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
KMT52718.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (274 aa)
KMT52716.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
KMT52715.1Protein nirG; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
KMT52743.1Protein nirL; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
KMT52714.1AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
KMT53321.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (324 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa)
KMT53493.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (249 aa)
KMT53491.1Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
KMT53473.1Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (337 aa)
cysGSirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (464 aa)
KMT54248.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
KMT54247.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
KMT54245.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
KMT54389.1BatB protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
KMT55422.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (429 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (341 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
cyoE-2Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (295 aa)
KMT56231.1Oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (400 aa)
KMT56012.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
KMT56608.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (310 aa)
KMT56486.1Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (299 aa)
KMT57008.1CrtK; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa)
KMT56765.1Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (203 aa)
KMT56697.1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (460 aa)
KMT56661.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
KMT56659.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (247 aa)
KMT57589.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
KMT57682.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
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