STRINGSTRING
KMT55562.1 KMT55562.1 dinG dinG KMT57384.1 KMT57384.1 recA recA KMT57635.1 KMT57635.1 KMT56635.1 KMT56635.1 KMT56787.1 KMT56787.1 uvrB uvrB recF recF KMT55861.1 KMT55861.1 KMT55386.1 KMT55386.1 uvrA uvrA KMT54962.1 KMT54962.1 KMT54718.1 KMT54718.1 lexA lexA KMT54579.1 KMT54579.1 KMT53872.1 KMT53872.1 ruvB ruvB ruvA ruvA dinB dinB KMT53545.1 KMT53545.1 KMT53553.1 KMT53553.1 KMT53538.1 KMT53538.1 uvrC uvrC lexA-2 lexA-2 KMT53023.1 KMT53023.1 KMT53024.1 KMT53024.1 KMT53027.1 KMT53027.1 KMT52727.1 KMT52727.1 KMT52497.1 KMT52497.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KMT55562.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1415 aa)
dinGATP-dependent DNA helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase. (714 aa)
KMT57384.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (827 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa)
KMT57635.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
KMT56635.1alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
KMT56787.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (708 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (671 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (367 aa)
KMT55861.1Copper chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
KMT55386.1Recombination and repair protein; May be involved in recombinational repair of damaged DNA. (557 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (944 aa)
KMT54962.1Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
KMT54718.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
lexALexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (202 aa)
KMT54579.1Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (157 aa)
KMT53872.1Phage antirepressor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (353 aa)
KMT53545.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
KMT53553.1Peptidase S24; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
KMT53538.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (607 aa)
lexA-2LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (205 aa)
KMT53023.1CDP-6-deoxy-delta-3,4-glucoseen reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
KMT53024.1DNA repair nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
KMT53027.1Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (839 aa)
KMT52727.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
KMT52497.1Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
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