STRINGSTRING
KMT53822.1 KMT53822.1 KMT53456.1 KMT53456.1 ubiD ubiD KMT53473.1 KMT53473.1 KMT53476.1 KMT53476.1 KMT53493.1 KMT53493.1 argH argH KMT53500.1 KMT53500.1 KMT53254.1 KMT53254.1 KMT53261.1 KMT53261.1 KMT53296.1 KMT53296.1 KMT53321.1 KMT53321.1 KMT53348.1 KMT53348.1 ilvA ilvA KMT53102.1 KMT53102.1 fabA fabA pyrF pyrF KMT52384.1 KMT52384.1 KMT52359.1 KMT52359.1 KMT52355.1 KMT52355.1 hdc hdc KMT52319.1 KMT52319.1 KMT52312.1 KMT52312.1 KMT52297.1 KMT52297.1 KMT52283.1 KMT52283.1 KMT52173.1 KMT52173.1 KMT52149.1 KMT52149.1 KMT52426.1 KMT52426.1 KMT52456.1 KMT52456.1 KMT52499.1 KMT52499.1 gudD gudD KMT52519.1 KMT52519.1 KMT52512.1 KMT52512.1 hisH-2 hisH-2 KMT52662.1 KMT52662.1 KMT52621.1 KMT52621.1 mltG mltG KMT52615.1 KMT52615.1 gfa gfa KMT52716.1 KMT52716.1 KMT52715.1 KMT52715.1 KMT52743.1 KMT52743.1 KMT52714.1 KMT52714.1 moaA moaA KMT52753.1 KMT52753.1 arnA arnA KMT52879.1 KMT52879.1 KMT52844.1 KMT52844.1 KMT52836.1 KMT52836.1 dapA-2 dapA-2 KMT52787.1 KMT52787.1 KMT52786.1 KMT52786.1 KMT53014.1 KMT53014.1 leuC leuC leuD leuD metZ metZ KMT57143.1 KMT57143.1 KMT57682.1 KMT57682.1 KMT57218.1 KMT57218.1 KMT57325.1 KMT57325.1 ispF ispF eno eno fabZ fabZ KMT57430.1 KMT57430.1 KMT57448.1 KMT57448.1 ppc ppc nth nth KMT57532.1 KMT57532.1 KMT57670.1 KMT57670.1 prpB prpB KMT56641.1 KMT56641.1 prpD prpD KMT56653.1 KMT56653.1 KMT56750.1 KMT56750.1 cobD cobD KMT56769.1 KMT56769.1 phhB phhB KMT56856.1 KMT56856.1 allA allA KMT56886.1 KMT56886.1 KMT56897.1 KMT56897.1 aroC aroC fumC fumC aroQ aroQ KMT56496.1 KMT56496.1 trpB trpB trpA trpA KMT56520.1 KMT56520.1 trpC trpC KMT56023.1 KMT56023.1 trpE trpE KMT56050.1 KMT56050.1 KMT56114.1 KMT56114.1 KMT56147.1 KMT56147.1 KMT56169.1 KMT56169.1 KMT56181.1 KMT56181.1 mutM mutM ilvD ilvD mltF mltF folX folX speA speA aroQ-2 aroQ-2 KMT55871.1 KMT55871.1 KMT55874.1 KMT55874.1 KMT55882.1 KMT55882.1 hemE hemE aroB aroB hutH hutH KMT55946.1 KMT55946.1 hutU hutU hisF hisF hisH hisH hisB hisB KMT55643.1 KMT55643.1 aspA aspA purK purK ubiC ubiC KMT55738.1 KMT55738.1 KMT55772.1 KMT55772.1 lysA lysA moaC moaC algL algL aspA-2 aspA-2 rlpA rlpA garD garD KMT55155.1 KMT55155.1 ectC ectC KMT55194.1 KMT55194.1 hemH hemH KMT55253.1 KMT55253.1 KMT55323.1 KMT55323.1 KMT55415.1 KMT55415.1 KMT55430.1 KMT55430.1 aroQ-3 aroQ-3 KMT55447.1 KMT55447.1 rlpA-2 rlpA-2 ubiX ubiX KMT55522.1 KMT55522.1 eutC eutC ribB ribB KMT54885.1 KMT54885.1 KMT54888.1 KMT54888.1 KMT54702.1 KMT54702.1 pckA pckA KMT54788.1 KMT54788.1 fadB fadB KMT54596.1 KMT54596.1 KMT54598.1 KMT54598.1 KMT54657.1 KMT54657.1 KMT54658.1 KMT54658.1 KMT54663.1 KMT54663.1 KMT54664.1 KMT54664.1 dapA dapA KMT54409.1 KMT54409.1 KMT54417.1 KMT54417.1 KMT54550.1 KMT54550.1 KMT54476.1 KMT54476.1 KMT53927.1 KMT53927.1 KMT53931.1 KMT53931.1 KMT53982.1 KMT53982.1 queE queE KMT54035.1 KMT54035.1 edd edd KMT54086.1 KMT54086.1 nnrD nnrD psd psd thiC thiC cysG cysG KMT53709.1 KMT53709.1 KMT53713.1 KMT53713.1 KMT53735.1 KMT53735.1 KMT53819.1 KMT53819.1 KMT53508.1 KMT53508.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KMT53822.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
KMT53456.1Calcium transporter ChaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (217 aa)
ubiD3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa)
KMT53473.1Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (337 aa)
KMT53476.1Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (221 aa)
KMT53493.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (249 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
KMT53500.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (946 aa)
KMT53254.1Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (365 aa)
KMT53261.1Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RNase T2 family. (209 aa)
KMT53296.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
KMT53321.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (324 aa)
KMT53348.16-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
KMT53102.1Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (591 aa)
fabA3-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa)
KMT52384.1P-hydroxycinnamoyl CoA hydratase/lyase; Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa)
KMT52359.15-dehydro-4-deoxyglucarate dehydratase; Catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (303 aa)
KMT52355.1Isochorismate-pyruvate lyase; Catalyzes the second reaction in the pyochelin biosynthetic pathway, the conversion of isochorismate to salicylate and pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
hdcHistidine decarboxylase; Catalyzes the formation of histamine from L-histidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KMT52319.1Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (289 aa)
KMT52312.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
KMT52297.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (578 aa)
KMT52283.1Dimethylallyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
KMT52173.1Lysine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (751 aa)
KMT52149.1Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
KMT52426.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
KMT52456.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (714 aa)
KMT52499.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
gudDGlucarate dehydratase; Catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
KMT52519.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
KMT52512.1Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (248 aa)
hisH-2Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
KMT52662.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KMT52621.14-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (377 aa)
KMT52615.1Radical SAM protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
gfaGlutathione-dependent formaldehyde-activating protein; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (192 aa)
KMT52716.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
KMT52715.1Protein nirG; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
KMT52743.1Protein nirL; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
KMT52714.1AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
KMT52753.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
arnAUDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (663 aa)
KMT52879.1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (173 aa)
KMT52844.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
KMT52836.1Dihydrodipicolinate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (316 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (287 aa)
KMT52787.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
KMT52786.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
KMT53014.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (214 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa)
KMT57143.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
KMT57682.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
KMT57218.1Ornithine cyclodeaminase; Catalyzes the formation of L-proline from L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
KMT57325.13-carboxy-cis,cis-muconate cycloisomerase; Catalyzes the cycloisomerization of cis,cis-muconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
KMT57430.1Thiamine biosynthesis protein ThiF; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
KMT57448.12-methylisocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (881 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa)
KMT57532.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (156 aa)
KMT57670.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
prpB2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (302 aa)
KMT56641.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (869 aa)
prpD2-methylcitrate dehydratase; Functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KMT56653.1Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa)
KMT56750.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa)
KMT56769.1Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
phhB4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
KMT56856.1Terpene utilization protein AtuA; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (167 aa)
KMT56886.1OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
KMT56897.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (363 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
KMT56496.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (243 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa)
KMT56520.12-dehydro-3-deoxy-6-phosphogalactonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
trpCIndole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (278 aa)
KMT56023.1Anthranilate synthase component II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (493 aa)
KMT56050.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)
KMT56114.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa)
KMT56147.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
KMT56169.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
KMT56181.1Transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (394 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (613 aa)
mltFMurein transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (486 aa)
folXD-erythro-7,8-dihydroneopterin triphosphate epimerase; Catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
aroQ-23-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa)
KMT55871.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
KMT55874.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
KMT55882.13-hydroxylacyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (366 aa)
hutHCatalyzes the degradation of histidine to urocanate and ammmonia; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
KMT55946.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (562 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
KMT55643.1Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (187 aa)
KMT55738.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
KMT55772.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (157 aa)
algLpoly(beta-D-mannuronate) lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family. (373 aa)
aspA-2Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (460 aa)
rlpALipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (123 aa)
garDGalactarate dehydrogenase; Catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
KMT55155.15-dehydro-4-deoxyglucarate dehydratase; Catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (303 aa)
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (128 aa)
KMT55194.1Ornithine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (341 aa)
KMT55253.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (478 aa)
KMT55323.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (214 aa)
KMT55415.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
KMT55430.1ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
aroQ-33-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
KMT55447.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
rlpA-2Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (332 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa)
KMT55522.1Ethanolamine ammonia-lyase; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
eutCEthanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (281 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa)
KMT54885.1Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
KMT54888.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
KMT54702.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (360 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
KMT54788.18-oxoguanine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
KMT54596.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa)
KMT54598.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)
KMT54657.14-hydroxyphenylacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KMT54658.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
KMT54663.12-oxo-hepta-3-ene-1,7-dioate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
KMT54664.1Catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (267 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
KMT54409.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (866 aa)
KMT54417.1Alanine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
KMT54550.1Peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (434 aa)
KMT54476.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (476 aa)
KMT53927.13-hydroxybutyryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
KMT53931.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
KMT53982.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa)
KMT54035.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
KMT54086.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
nnrDCarbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (286 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (286 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (634 aa)
cysGSirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (464 aa)
KMT53709.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa)
KMT53713.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
KMT53735.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (246 aa)
KMT53819.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
KMT53508.1Glycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (473 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
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