STRINGSTRING
rlmJ rlmJ KMT56718.1 KMT56718.1 KMT56674.1 KMT56674.1 rlmL rlmL rlmF rlmF KMT55930.1 KMT55930.1 KMT55960.1 KMT55960.1 KMT55730.1 KMT55730.1 rph rph rsmH rsmH rsmI rsmI rsmC rsmC KMT55140.1 KMT55140.1 KMT55223.1 KMT55223.1 KMT55362.1 KMT55362.1 rbfA rbfA rimP rimP rlmE rlmE KMT55377.1 KMT55377.1 rlmG rlmG rsmD rsmD KMT56217.1 KMT56217.1 KMT56192.1 KMT56192.1 rhlE rhlE rsmA rsmA rsmG rsmG KMT56535.1 KMT56535.1 KMT56875.1 KMT56875.1 rlmD rlmD KMT56733.1 KMT56733.1 KMT55471.1 KMT55471.1 KMT55476.1 KMT55476.1 ybeY ybeY rlmH rlmH rsfS rsfS deaD deaD rlmM rlmM KMT53959.1 KMT53959.1 rlmB rlmB rsgA rsgA KMT53372.1 KMT53372.1 KMT52628.1 KMT52628.1 KMT52632.1 KMT52632.1 rne rne der der rlmN rlmN KMT56317.1 KMT56317.1 obgE obgE rnc rnc era era rsmJ rsmJ KMT57272.1 KMT57272.1 rplT rplT rimM rimM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rlmJLactate dehydrogenase; Specifically methylates the adenine in position 2030 of 23S rRNA. (278 aa)
KMT56718.1ATP-dependent helicase HrpA; Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; Derived by automated computational analysis using gene prediction method: Protein Homology. (1303 aa)
KMT56674.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
rlmL50S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (756 aa)
rlmF23S rRNA methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (340 aa)
KMT55930.116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (235 aa)
KMT55960.1GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)
KMT55730.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (240 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (315 aa)
rsmIMethyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (290 aa)
rsmC16S rRNA methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (332 aa)
KMT55140.1Involved in the processing of the 5'end of 16S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
KMT55223.1Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (320 aa)
KMT55362.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily. (338 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa)
rimPRibosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (152 aa)
rlmE23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (216 aa)
KMT55377.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
rlmG50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (374 aa)
rsmD16S rRNA methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (205 aa)
KMT56217.1Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (145 aa)
KMT56192.116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (239 aa)
rhlEDEAD/DEAH box helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (629 aa)
rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (270 aa)
rsmG16S rRNA methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (214 aa)
KMT56535.116S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (436 aa)
KMT56875.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
rlmD23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (450 aa)
KMT56733.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (448 aa)
KMT55471.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (835 aa)
KMT55476.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (211 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (152 aa)
rlmH50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa)
rsfSRibosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (164 aa)
deaDRNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (557 aa)
rlmM23S rRNA methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (358 aa)
KMT53959.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (414 aa)
rlmB23S rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (251 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (343 aa)
KMT53372.1GTPase SAR1; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
KMT52628.1Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
KMT52632.123S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1068 aa)
derGTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (489 aa)
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa)
KMT56317.1Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily. (271 aa)
obgEGTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (407 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (229 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
rsmJSAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (260 aa)
KMT57272.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (230 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (178 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
Server load: low (22%) [HD]