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pdxH pdxH KMT57103.1 KMT57103.1 KMT57143.1 KMT57143.1 KMT57192.1 KMT57192.1 KMT57234.1 KMT57234.1 KMT57235.1 KMT57235.1 KMT57328.1 KMT57328.1 KMT57396.1 KMT57396.1 glpK glpK glpD glpD KMT57586.1 KMT57586.1 pdxJ pdxJ serC serC KMT56647.1 KMT56647.1 phhB phhB lldD lldD aroE aroE pdxY pdxY KMT56025.1 KMT56025.1 pdxA pdxA glpE glpE KMT56106.1 KMT56106.1 gapA gapA thiG thiG KMT56236.1 KMT56236.1 KMT56317.1 KMT56317.1 folX folX KMT56389.1 KMT56389.1 KMT56405.1 KMT56405.1 thiI thiI KMT56005.1 KMT56005.1 KMT55970.1 KMT55970.1 KMT54993.1 KMT54993.1 KMT55625.1 KMT55625.1 KMT55394.1 KMT55394.1 KMT55415.1 KMT55415.1 aroE-2 aroE-2 KMT55447.1 KMT55447.1 KMT55633.1 KMT55633.1 thiE thiE KMT55522.1 KMT55522.1 eutC eutC dxs dxs thiL thiL iolG iolG KMT54883.1 KMT54883.1 KMT54884.1 KMT54884.1 KMT54885.1 KMT54885.1 KMT54900.1 KMT54900.1 KMT54901.1 KMT54901.1 KMT54904.1 KMT54904.1 KMT54905.1 KMT54905.1 cysQ cysQ pdxB pdxB KMT54633.1 KMT54633.1 KMT54657.1 KMT54657.1 KMT54658.1 KMT54658.1 KMT54392.1 KMT54392.1 KMT53891.1 KMT53891.1 KMT54027.1 KMT54027.1 thiC thiC KMT54360.1 KMT54360.1 KMT53618.1 KMT53618.1 KMT53863.1 KMT53863.1 KMT53864.1 KMT53864.1 KMT53794.1 KMT53794.1 KMT53818.1 KMT53818.1 cpdA-2 cpdA-2 KMT53334.1 KMT53334.1 KMT53391.1 KMT53391.1 KMT53392.1 KMT53392.1 lldD-2 lldD-2 KMT53037.1 KMT53037.1 KMT53038.1 KMT53038.1 KMT53039.1 KMT53039.1 KMT52990.1 KMT52990.1 KMT52804.1 KMT52804.1 KMT52879.1 KMT52879.1 KMT52895.1 KMT52895.1 KMT52978.1 KMT52978.1 KMT52961.1 KMT52961.1 pdxH-2 pdxH-2 KMT52683.1 KMT52683.1 KMT52566.1 KMT52566.1 KMT52588.1 KMT52588.1 KMT52641.1 KMT52641.1 KMT52149.1 KMT52149.1 gloB gloB KMT52283.1 KMT52283.1 KMT52410.1 KMT52410.1 KMT52355.1 KMT52355.1 KMT52379.1 KMT52379.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdxHPyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa)
KMT57103.1Butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KMT57143.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
KMT57192.1Iditol 2-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
KMT57234.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
KMT57235.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
KMT57328.1Protocatechuate 3,4-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
KMT57396.1Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa)
glpDGlycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (512 aa)
KMT57586.1Glucose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (247 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
KMT56647.1Sulfurylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
phhB4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
lldDLactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (380 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
pdxYPyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (290 aa)
KMT56025.1Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (272 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa)
glpESulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (109 aa)
KMT56106.1Aldehyde dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (351 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)
KMT56236.1Thiamine biosynthesis protein ThiS; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
KMT56317.1Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily. (271 aa)
folXD-erythro-7,8-dihydroneopterin triphosphate epimerase; Catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
KMT56389.1Bleomycin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
KMT56405.1Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
thiItRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa)
KMT56005.1Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa)
KMT55970.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
KMT54993.1Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
KMT55625.1D-amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
KMT55394.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (936 aa)
KMT55415.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
KMT55447.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
KMT55633.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (209 aa)
KMT55522.1Ethanolamine ammonia-lyase; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
eutCEthanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (281 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (321 aa)
iolGInositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (336 aa)
KMT54883.13D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (643 aa)
KMT54884.15-deoxyglucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
KMT54885.1Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
KMT54900.1Quinonprotein alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
KMT54901.1Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
KMT54904.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
KMT54905.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
cysQAdenosine-3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (278 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (380 aa)
KMT54633.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
KMT54657.14-hydroxyphenylacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KMT54658.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
KMT54392.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KMT53891.1Fatty acid hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
KMT54027.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (634 aa)
KMT54360.1Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (493 aa)
KMT53618.1Glycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (491 aa)
KMT53863.12-pyrone-4,6-dicarboxylate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
KMT53864.1PrpF protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
KMT53794.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KMT53818.1Quinohemoprotein alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
cpdA-2Metallophosphatase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (277 aa)
KMT53334.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
KMT53391.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
KMT53392.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
lldD-2Lactate dehydrogenase; Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
KMT53037.1Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
KMT53038.1With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
KMT53039.1Iditol 2-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KMT52990.16-chlorohydroxyquinol-1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KMT52804.1Acetylglucosaminylphosphatidylinositol deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
KMT52879.1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (173 aa)
KMT52895.1Protein QbdB; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KMT52978.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. (250 aa)
KMT52961.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
pdxH-2Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa)
KMT52683.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
KMT52566.1Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
KMT52588.1Glycerol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
KMT52641.14'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (238 aa)
KMT52149.1Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (255 aa)
KMT52283.1Dimethylallyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
KMT52410.1Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
KMT52355.1Isochorismate-pyruvate lyase; Catalyzes the second reaction in the pyochelin biosynthetic pathway, the conversion of isochorismate to salicylate and pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
KMT52379.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
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