(16 nodes) Ribonuclease H-like superfamily network (Pseudomonas sp. KG01)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rnhB	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (210 aa)
	rnt	Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (223 aa)
	KMT56850.1	Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (923 aa)
	KMT56088.1	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	KMT56217.1	Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (145 aa)
	KMT55466.1	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
	KMT54969.1	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
	KMT54732.1	Transcription accessory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (777 aa)
	rnd	Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (377 aa)
	ruvC	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (174 aa)
	sbcB	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
	orn	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (180 aa)
	KMT52497.1	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
	rnhA	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)
	dnaQ	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (248 aa)

Your Current Organism:

Pseudomonas sp. KG01

NCBI taxonomy Id: 1674920
Other names: P. sp. KG01

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KMT52497.1	polA	ACR52_26980	ACR52_05670	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.995
KMT52497.1	rnhA	ACR52_26980	ACR52_27575	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.406
KMT52497.1	rnhB	ACR52_26980	ACR52_01950	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.851
KMT55466.1	KMT56088.1	ACR52_12985	ACR52_06840	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.825
KMT55466.1	dnaQ	ACR52_12985	ACR52_27580	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.837
KMT55466.1	orn	ACR52_12985	ACR52_18680	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	0.679
KMT55466.1	polA	ACR52_12985	ACR52_05670	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.672
KMT55466.1	rnd	ACR52_12985	ACR52_15795	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.	0.539
KMT55466.1	rnhA	ACR52_12985	ACR52_27575	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.538
KMT56088.1	KMT55466.1	ACR52_06840	ACR52_12985	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.825
KMT56088.1	dnaQ	ACR52_06840	ACR52_27580	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.774
KMT56088.1	polA	ACR52_06840	ACR52_05670	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.548
KMT56088.1	rnhB	ACR52_06840	ACR52_01950	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.464
KMT56088.1	rnt	ACR52_06840	ACR52_02560	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.	0.615
dnaQ	KMT55466.1	ACR52_27580	ACR52_12985	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
dnaQ	KMT56088.1	ACR52_27580	ACR52_06840	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
dnaQ	orn	ACR52_27580	ACR52_18680	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	0.749
dnaQ	polA	ACR52_27580	ACR52_05670	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.720
dnaQ	rnd	ACR52_27580	ACR52_15795	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.	0.539
dnaQ	rnhA	ACR52_27580	ACR52_27575	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.972