STRINGSTRING
ruvA ruvA KMT57405.1 KMT57405.1 recA recA rnt rnt recO recO KMT57613.1 KMT57613.1 KMT57645.1 KMT57645.1 dnaX dnaX recR recR polA polA recF recF KMT56547.1 KMT56547.1 surA surA KMT56088.1 KMT56088.1 recD recD recB recB recC recC priA priA KMT55987.1 KMT55987.1 recG recG KMT55466.1 KMT55466.1 KMT55493.1 KMT55493.1 KMT55572.1 KMT55572.1 KMT54939.1 KMT54939.1 KMT54838.1 KMT54838.1 KMT54589.1 KMT54589.1 KMT53929.1 KMT53929.1 ruvB ruvB ruvC ruvC KMT54081.1 KMT54081.1 KMT54256.1 KMT54256.1 KMT53610.1 KMT53610.1 KMT53058.1 KMT53058.1 KMT53023.1 KMT53023.1 dnaE2 dnaE2 KMT52770.1 KMT52770.1 KMT52618.1 KMT52618.1 KMT52151.1 KMT52151.1 KMT52161.1 KMT52161.1 dnaQ dnaQ KMT52249.1 KMT52249.1 KMT52406.1 KMT52406.1 KMT52110.1 KMT52110.1 KMT52107.1 KMT52107.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
KMT57405.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1173 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa)
rntRibonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (223 aa)
recODNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. (229 aa)
KMT57613.1DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
KMT57645.1AbrB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (697 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (923 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (367 aa)
KMT56547.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
surAMolecular chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (446 aa)
KMT56088.1DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (689 aa)
recBExodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] (1224 aa)
recCExodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1150 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (739 aa)
KMT55987.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (691 aa)
KMT55466.1DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
KMT55493.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
KMT55572.1Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (171 aa)
KMT54939.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
KMT54838.1Cell division protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KMT54589.1Fic family filamentation induced by cAMP cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
KMT53929.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (174 aa)
KMT54081.1ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
KMT54256.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KMT53610.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
KMT53058.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
KMT53023.1CDP-6-deoxy-delta-3,4-glucoseen reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
dnaE2DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1023 aa)
KMT52770.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
KMT52618.1DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
KMT52151.1Peptidylprolyl isomerase; Rotamase C; accelerates isomerization of the peptidyl prolyl bond; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
KMT52161.1Peptidylprolyl isomerase; Rotamase C; accelerates isomerization of the peptidyl prolyl bond; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (248 aa)
KMT52249.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
KMT52406.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
KMT52110.1DNA polymerase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
KMT52107.1Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
Your Current Organism:
Pseudomonas sp. KG01
NCBI taxonomy Id: 1674920
Other names: P. sp. KG01
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.