(10 nodes) Regulation of BACH1 activity, and D domain of beta-TrCP network (Paramormyrops kingsleyae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (403 aa)
	cand1	Cullin-associated and neddylation-dissociated 1. (1230 aa)
	LOC111855000	Cullin 1a; Belongs to the cullin family. (777 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (765 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	LOC111834692	Uncharacterized protein. (575 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	FBXW7	F-box and WD repeat domain containing 7. (747 aa)
	ENSPKIP00000037247	FBA domain-containing protein. (174 aa)
	FBXW11	F-box and WD repeat domain containing 11. (557 aa)

Your Current Organism:

Paramormyrops kingsleyae

NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL1	ENSPKIP00000037247	ENSPKIP00000014421	ENSPKIP00000037247	Cullin 1; Belongs to the cullin family.	FBA domain-containing protein.	0.812
CUL1	FBXW11	ENSPKIP00000014421	ENSPKIP00000039600	Cullin 1; Belongs to the cullin family.	F-box and WD repeat domain containing 11.	0.991
CUL1	FBXW7	ENSPKIP00000014421	ENSPKIP00000034528	Cullin 1; Belongs to the cullin family.	F-box and WD repeat domain containing 7.	0.761
CUL1	LOC111834692	ENSPKIP00000014421	ENSPKIP00000018245	Cullin 1; Belongs to the cullin family.	Uncharacterized protein.	0.991
CUL1	LOC111855000	ENSPKIP00000014421	ENSPKIP00000013816	Cullin 1; Belongs to the cullin family.	Cullin 1a; Belongs to the cullin family.	0.900
CUL1	RBX1	ENSPKIP00000014421	ENSPKIP00000017898	Cullin 1; Belongs to the cullin family.	RING-type domain-containing protein.	0.993
CUL1	cand1	ENSPKIP00000014421	ENSPKIP00000005665	Cullin 1; Belongs to the cullin family.	Cullin-associated and neddylation-dissociated 1.	0.909
CUL1	skp1	ENSPKIP00000014421	ENSPKIP00000019570	Cullin 1; Belongs to the cullin family.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.993
CUL1	skp2	ENSPKIP00000014421	ENSPKIP00000001638	Cullin 1; Belongs to the cullin family.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.994
ENSPKIP00000037247	CUL1	ENSPKIP00000037247	ENSPKIP00000014421	FBA domain-containing protein.	Cullin 1; Belongs to the cullin family.	0.812
ENSPKIP00000037247	FBXW11	ENSPKIP00000037247	ENSPKIP00000039600	FBA domain-containing protein.	F-box and WD repeat domain containing 11.	0.919
ENSPKIP00000037247	FBXW7	ENSPKIP00000037247	ENSPKIP00000034528	FBA domain-containing protein.	F-box and WD repeat domain containing 7.	0.921
ENSPKIP00000037247	LOC111834692	ENSPKIP00000037247	ENSPKIP00000018245	FBA domain-containing protein.	Uncharacterized protein.	0.919
ENSPKIP00000037247	LOC111855000	ENSPKIP00000037247	ENSPKIP00000013816	FBA domain-containing protein.	Cullin 1a; Belongs to the cullin family.	0.812
ENSPKIP00000037247	RBX1	ENSPKIP00000037247	ENSPKIP00000017898	FBA domain-containing protein.	RING-type domain-containing protein.	0.645
ENSPKIP00000037247	cand1	ENSPKIP00000037247	ENSPKIP00000005665	FBA domain-containing protein.	Cullin-associated and neddylation-dissociated 1.	0.547
ENSPKIP00000037247	skp1	ENSPKIP00000037247	ENSPKIP00000019570	FBA domain-containing protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.923
ENSPKIP00000037247	skp2	ENSPKIP00000037247	ENSPKIP00000001638	FBA domain-containing protein.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.944
FBXW11	CUL1	ENSPKIP00000039600	ENSPKIP00000014421	F-box and WD repeat domain containing 11.	Cullin 1; Belongs to the cullin family.	0.991
FBXW11	ENSPKIP00000037247	ENSPKIP00000039600	ENSPKIP00000037247	F-box and WD repeat domain containing 11.	FBA domain-containing protein.	0.919