(10 nodes) Synuclein, and Seven in absentia protein family network (Paramormyrops kingsleyae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Known Interactions

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Your Input:
	TPPP	Tubulin polymerization promoting protein. (260 aa)
	LOC111848108	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (286 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (129 aa)
	cacybp	Calcyclin binding protein. (245 aa)
	siah1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (337 aa)
	LOC111838250	Uncharacterized protein; Belongs to the synuclein family. (141 aa)
	SNCG	Gamma-synuclein; Belongs to the synuclein family. (127 aa)
	LOC111848512	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (244 aa)
	SIAH2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (301 aa)
	sncaip	Synuclein, alpha interacting protein. (862 aa)

Your Current Organism:

Paramormyrops kingsleyae

NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111838250	LOC111848108	ENSPKIP00000022156	ENSPKIP00000005156	Uncharacterized protein; Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.623
LOC111838250	SIAH2	ENSPKIP00000022156	ENSPKIP00000035926	Uncharacterized protein; Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.623
LOC111838250	TPPP	ENSPKIP00000022156	ENSPKIP00000000722	Uncharacterized protein; Belongs to the synuclein family.	Tubulin polymerization promoting protein.	0.739
LOC111838250	siah1	ENSPKIP00000022156	ENSPKIP00000016661	Uncharacterized protein; Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.623
LOC111838250	sncaip	ENSPKIP00000022156	ENSPKIP00000041489	Uncharacterized protein; Belongs to the synuclein family.	Synuclein, alpha interacting protein.	0.958
LOC111838250	sncb	ENSPKIP00000022156	ENSPKIP00000006163	Uncharacterized protein; Belongs to the synuclein family.	Beta-synuclein; Belongs to the synuclein family.	0.527
LOC111848108	LOC111838250	ENSPKIP00000005156	ENSPKIP00000022156	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Uncharacterized protein; Belongs to the synuclein family.	0.623
LOC111848108	LOC111848512	ENSPKIP00000005156	ENSPKIP00000031621	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	0.443
LOC111848108	SNCG	ENSPKIP00000005156	ENSPKIP00000030763	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Gamma-synuclein; Belongs to the synuclein family.	0.443
LOC111848108	cacybp	ENSPKIP00000005156	ENSPKIP00000008447	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Calcyclin binding protein.	0.970
LOC111848108	siah1	ENSPKIP00000005156	ENSPKIP00000016661	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.900
LOC111848108	sncaip	ENSPKIP00000005156	ENSPKIP00000041489	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Synuclein, alpha interacting protein.	0.497
LOC111848512	LOC111848108	ENSPKIP00000031621	ENSPKIP00000005156	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.443
LOC111848512	SIAH2	ENSPKIP00000031621	ENSPKIP00000035926	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.443
LOC111848512	TPPP	ENSPKIP00000031621	ENSPKIP00000000722	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	Tubulin polymerization promoting protein.	0.513
LOC111848512	siah1	ENSPKIP00000031621	ENSPKIP00000016661	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.443
LOC111848512	sncaip	ENSPKIP00000031621	ENSPKIP00000041489	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	Synuclein, alpha interacting protein.	0.798
LOC111848512	sncb	ENSPKIP00000031621	ENSPKIP00000006163	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	Beta-synuclein; Belongs to the synuclein family.	0.563
SIAH2	LOC111838250	ENSPKIP00000035926	ENSPKIP00000022156	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Uncharacterized protein; Belongs to the synuclein family.	0.623
SIAH2	LOC111848512	ENSPKIP00000035926	ENSPKIP00000031621	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.	0.443