(70 nodes) SCF ubiquitin ligase complex network (Paramormyrops kingsleyae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111835693	Si:dkey-76k16.6. (274 aa)
	ENSPKIP00000003070	F-box and leucine-rich repeat protein 20. (417 aa)
	FBXL13	F-box and leucine rich repeat protein 13. (453 aa)
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (403 aa)
	Fbxo45	F-box protein 45. (336 aa)
	spsb4	SplA/ryanodine receptor domain and SOCS box containing 4a. (350 aa)
	LOC111850858	Uncharacterized protein. (484 aa)
	LOC111837818	F-box domain-containing protein. (477 aa)
	fbxo33	F-box protein 33. (485 aa)
	fbxo42	F-box protein 42. (712 aa)
	fbxl18	F-box and leucine-rich repeat protein 18. (724 aa)
	LOC111834356	Uncharacterized protein. (275 aa)
	FBXL14-2	F-box and leucine rich repeat protein 14. (414 aa)
	FBXL14	F-box and leucine-rich repeat protein 14b. (400 aa)
	fbh1	F-box DNA helicase 1. (1055 aa)
	cacybp	Calcyclin binding protein. (245 aa)
	LOC111851803	Leucine rich repeat containing 29. (644 aa)
	Fbxl6	F-box domain-containing protein. (530 aa)
	cul2	Cullin 2; Belongs to the cullin family. (745 aa)
	fbxl2	F-box and leucine-rich repeat protein 2. (432 aa)
	fbxo31	F-box protein 31. (575 aa)
	LOC111836627	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
	ENSPKIP00000026851	Ring-box 1, E3 ubiquitin protein ligase. (112 aa)
	nccrp1	Non-specific cytotoxic cell receptor protein 1. (236 aa)
	LOC111849171	F-box and leucine-rich repeat protein 16. (484 aa)
	fbxl4	F-box and leucine-rich repeat protein 4. (612 aa)
	FBXL20	F-box and leucine-rich repeat protein 20. (380 aa)
	LOC111834692	Uncharacterized protein. (575 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	fbxl12	F-box domain-containing protein. (394 aa)
	LOC111853418	F-box protein 42. (691 aa)
	LOC111858197	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (82 aa)
	fbxw4	F-box and WD repeat domain containing 4. (391 aa)
	fbxl8	F-box and leucine-rich repeat protein 8. (383 aa)
	Fbxo7	F-box protein 7. (508 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (765 aa)
	LOC111833426	F-box and leucine-rich repeat protein 3, like. (458 aa)
	LOC111855000	Cullin 1a; Belongs to the cullin family. (777 aa)
	amn1	Antagonist of mitotic exit network 1 homolog (S. cerevisiae). (258 aa)
	Fbxl17	F-box and leucine-rich repeat protein 17. (352 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (219 aa)
	fbxw5	F-box and WD repeat domain containing 5. (597 aa)
	SKP1	Uncharacterized protein; Belongs to the SKP1 family. (164 aa)
	fbxo4	F-box protein 4. (417 aa)
	FBXW11	F-box and WD repeat domain containing 11. (557 aa)
	ENSPKIP00000039216	Si:ch1073-228j22.2. (263 aa)
	daw1	Dynein assembly factor with WDR repeat domains 1. (415 aa)
	LOC111847422	SplA/ryanodine receptor domain and SOCS box containing 4a. (277 aa)
	fbxo9	F-box protein 9. (429 aa)
	spsb1	SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
	fbxw8	F-box and WD repeat domain containing 8. (617 aa)
	LOC111834354	Uncharacterized protein. (263 aa)
	Usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1386 aa)
	dmac2	Si:ch1073-228b5.2. (301 aa)
	spsb3	SplA/ryanodine receptor domain and SOCS box containing 3a. (365 aa)
	LOC111850730	Uncharacterized protein. (841 aa)
	fbxl22	F-box and leucine-rich repeat protein 22. (243 aa)
	fbxl15	F-box and leucine-rich repeat protein 15. (292 aa)
	LOC111838700	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
	fbxo25	F-box protein 25. (364 aa)
	fbxl5	F-box and leucine-rich repeat protein 5. (661 aa)
	fbxl3	F-box and leucine-rich repeat protein 3a. (432 aa)
	fbxo15	F-box domain-containing protein. (509 aa)
	tmem183a	Transmembrane protein 183A. (366 aa)
	ccnf	Cyclin F; Belongs to the cyclin family. (782 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	fbxo48	F-box protein 48. (164 aa)
	ENSPKIP00000037247	FBA domain-containing protein. (174 aa)
	Fbxo32	F-box protein 32. (393 aa)
	fbxl7	F-box and leucine-rich repeat protein 7. (506 aa)

Your Current Organism:

Paramormyrops kingsleyae

NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL1	ENSPKIP00000003070	ENSPKIP00000014421	ENSPKIP00000003070	Cullin 1; Belongs to the cullin family.	F-box and leucine-rich repeat protein 20.	0.770
CUL1	ENSPKIP00000026851	ENSPKIP00000014421	ENSPKIP00000026851	Cullin 1; Belongs to the cullin family.	Ring-box 1, E3 ubiquitin protein ligase.	0.935
CUL1	ENSPKIP00000037247	ENSPKIP00000014421	ENSPKIP00000037247	Cullin 1; Belongs to the cullin family.	FBA domain-containing protein.	0.812
CUL1	ENSPKIP00000039216	ENSPKIP00000014421	ENSPKIP00000039216	Cullin 1; Belongs to the cullin family.	Si:ch1073-228j22.2.	0.553
CUL1	FBXL13	ENSPKIP00000014421	ENSPKIP00000002851	Cullin 1; Belongs to the cullin family.	F-box and leucine rich repeat protein 13.	0.750
CUL1	FBXL14	ENSPKIP00000014421	ENSPKIP00000012627	Cullin 1; Belongs to the cullin family.	F-box and leucine-rich repeat protein 14b.	0.727
CUL1	FBXL14-2	ENSPKIP00000014421	ENSPKIP00000013858	Cullin 1; Belongs to the cullin family.	F-box and leucine rich repeat protein 14.	0.727
CUL1	FBXL17	ENSPKIP00000014421	ENSPKIP00000040864	Cullin 1; Belongs to the cullin family.	F-box and leucine rich repeat protein 17.	0.870
CUL1	FBXL20	ENSPKIP00000014421	ENSPKIP00000003951	Cullin 1; Belongs to the cullin family.	F-box and leucine-rich repeat protein 20.	0.526
CUL1	FBXW11	ENSPKIP00000014421	ENSPKIP00000039600	Cullin 1; Belongs to the cullin family.	F-box and WD repeat domain containing 11.	0.991
CUL1	Fbxl17	ENSPKIP00000014421	ENSPKIP00000040893	Cullin 1; Belongs to the cullin family.	F-box and leucine-rich repeat protein 17.	0.870
CUL1	Fbxl6	ENSPKIP00000014421	ENSPKIP00000037090	Cullin 1; Belongs to the cullin family.	F-box domain-containing protein.	0.761
CUL1	Fbxo32	ENSPKIP00000014421	ENSPKIP00000037229	Cullin 1; Belongs to the cullin family.	F-box protein 32.	0.766
CUL1	Fbxo45	ENSPKIP00000014421	ENSPKIP00000026873	Cullin 1; Belongs to the cullin family.	F-box protein 45.	0.831
CUL1	Fbxo7	ENSPKIP00000014421	ENSPKIP00000014985	Cullin 1; Belongs to the cullin family.	F-box protein 7.	0.610
CUL1	LOC111833426	ENSPKIP00000014421	ENSPKIP00000014267	Cullin 1; Belongs to the cullin family.	F-box and leucine-rich repeat protein 3, like.	0.642
CUL1	LOC111834354	ENSPKIP00000014421	ENSPKIP00000030702	Cullin 1; Belongs to the cullin family.	Uncharacterized protein.	0.653
CUL1	LOC111834356	ENSPKIP00000014421	ENSPKIP00000030617	Cullin 1; Belongs to the cullin family.	Uncharacterized protein.	0.653
CUL1	LOC111834692	ENSPKIP00000014421	ENSPKIP00000018245	Cullin 1; Belongs to the cullin family.	Uncharacterized protein.	0.991
CUL1	LOC111835693	ENSPKIP00000014421	ENSPKIP00000003674	Cullin 1; Belongs to the cullin family.	Si:dkey-76k16.6.	0.551