(15 nodes) Regulation of DNA methylation-dependent heterochromatin assembly network (Paramormyrops kingsleyae)

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second shell of interactors

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Your Input:
	ENSPKIP00000028718	Cytosine-specific methyltransferase. (497 aa)
	TASOR	Transcription activation suppressor a. (1839 aa)
	setdb1	SET domain bifurcated histone lysine methyltransferase 1b. (1260 aa)
	LOC111849208	SAM domain-containing protein. (697 aa)
	Kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (851 aa)
	ENSPKIP00000037174	Uncharacterized protein. (203 aa)
	LOC111840960	Sterile alpha motif domain containing 1b. (698 aa)
	LOC111842287	Uncharacterized protein. (316 aa)
	Aicda	Activation-induced cytidine deaminase. (189 aa)
	LOC111837625	Activating transcription factor 7 interacting protein. (1034 aa)
	LOC111855685	DUF3715 domain-containing protein. (1644 aa)
	LOC111853180	Fibronectin type-III domain-containing protein. (953 aa)
	Morc2	MORC family CW-type zinc finger 2. (822 aa)
	ENSPKIP00000027144	DDE_Tnp_1_7 domain-containing protein. (413 aa)
	LOC111855700	Uncharacterized protein. (616 aa)

Your Current Organism:

Paramormyrops kingsleyae

NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPKIP00000027144	LOC111855700	ENSPKIP00000027144	ENSPKIP00000027952	DDE_Tnp_1_7 domain-containing protein.	Uncharacterized protein.	0.854
ENSPKIP00000027144	setdb1	ENSPKIP00000027144	ENSPKIP00000029908	DDE_Tnp_1_7 domain-containing protein.	SET domain bifurcated histone lysine methyltransferase 1b.	0.854
ENSPKIP00000028718	ENSPKIP00000037174	ENSPKIP00000028718	ENSPKIP00000037174	Cytosine-specific methyltransferase.	Uncharacterized protein.	0.950
ENSPKIP00000028718	Kdm1a	ENSPKIP00000028718	ENSPKIP00000035773	Cytosine-specific methyltransferase.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.668
ENSPKIP00000028718	LOC111855700	ENSPKIP00000028718	ENSPKIP00000027952	Cytosine-specific methyltransferase.	Uncharacterized protein.	0.419
ENSPKIP00000028718	setdb1	ENSPKIP00000028718	ENSPKIP00000029908	Cytosine-specific methyltransferase.	SET domain bifurcated histone lysine methyltransferase 1b.	0.419
ENSPKIP00000037174	ENSPKIP00000028718	ENSPKIP00000037174	ENSPKIP00000028718	Uncharacterized protein.	Cytosine-specific methyltransferase.	0.950
ENSPKIP00000037174	Kdm1a	ENSPKIP00000037174	ENSPKIP00000035773	Uncharacterized protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.668
ENSPKIP00000037174	LOC111855700	ENSPKIP00000037174	ENSPKIP00000027952	Uncharacterized protein.	Uncharacterized protein.	0.419
ENSPKIP00000037174	setdb1	ENSPKIP00000037174	ENSPKIP00000029908	Uncharacterized protein.	SET domain bifurcated histone lysine methyltransferase 1b.	0.419
Kdm1a	ENSPKIP00000028718	ENSPKIP00000035773	ENSPKIP00000028718	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Cytosine-specific methyltransferase.	0.668
Kdm1a	ENSPKIP00000037174	ENSPKIP00000035773	ENSPKIP00000037174	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.668
Kdm1a	LOC111855700	ENSPKIP00000035773	ENSPKIP00000027952	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.451
Kdm1a	setdb1	ENSPKIP00000035773	ENSPKIP00000029908	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	SET domain bifurcated histone lysine methyltransferase 1b.	0.455
LOC111837625	LOC111855700	ENSPKIP00000016077	ENSPKIP00000027952	Activating transcription factor 7 interacting protein.	Uncharacterized protein.	0.901
LOC111837625	setdb1	ENSPKIP00000016077	ENSPKIP00000029908	Activating transcription factor 7 interacting protein.	SET domain bifurcated histone lysine methyltransferase 1b.	0.901
LOC111842287	LOC111855685	ENSPKIP00000009887	ENSPKIP00000020368	Uncharacterized protein.	DUF3715 domain-containing protein.	0.860
LOC111842287	TASOR	ENSPKIP00000009887	ENSPKIP00000029618	Uncharacterized protein.	Transcription activation suppressor a.	0.860
LOC111853180	LOC111855700	ENSPKIP00000023548	ENSPKIP00000027952	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.901
LOC111853180	setdb1	ENSPKIP00000023548	ENSPKIP00000029908	Fibronectin type-III domain-containing protein.	SET domain bifurcated histone lysine methyltransferase 1b.	0.901