(24 nodes) Bone cell development network (Paramormyrops kingsleyae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPKIP00000040839	Glycoprotein IX (platelet). (266 aa)
	ENSPKIP00000039161	Abl interactor 1. (418 aa)
	LOC111836858	Serum response factor a. (601 aa)
	lrrk1	Leucine-rich repeat kinase 1. (1998 aa)
	LOC111855927	Fam20C domain-containing protein. (549 aa)
	Med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1838 aa)
	LOC111835754	Serum response factor b. (598 aa)
	sh2b3	SH2B adaptor protein 3. (656 aa)
	LOC111850568	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	ENSPKIP00000007905	Protein tyrosine phosphatase non-receptor type 11a. (578 aa)
	ENSPKIP00000009283	ATPase H+ transporting accessory protein 1a. (428 aa)
	Gp1bb	Glycoprotein Ib platelet subunit beta. (216 aa)
	LOC111853334	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	fam20c	FAM20C golgi associated secretory pathway kinase b. (568 aa)
	LOC111835923	Tyrosine-protein kinase. (529 aa)
	LOC111845232	Uncharacterized protein. (2683 aa)
	ENSPKIP00000019866	Homeobox domain-containing protein. (382 aa)
	atp6ap1	ATPase H+ transporting accessory protein 1b. (464 aa)
	LOC111855741	Tyrosine-protein kinase. (551 aa)
	LOC111846947	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (267 aa)
	ptpn6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa)
	EP300	E1A binding protein p300. (2557 aa)
	ABI1	Abl interactor 1. (524 aa)
	LOC111852751	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (263 aa)

Your Current Organism:

Paramormyrops kingsleyae

NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPKIP00000007905	LOC111835923	ENSPKIP00000007905	ENSPKIP00000017997	Protein tyrosine phosphatase non-receptor type 11a.	Tyrosine-protein kinase.	0.538
ENSPKIP00000007905	LOC111850568	ENSPKIP00000007905	ENSPKIP00000007894	Protein tyrosine phosphatase non-receptor type 11a.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.900
ENSPKIP00000007905	LOC111853334	ENSPKIP00000007905	ENSPKIP00000013653	Protein tyrosine phosphatase non-receptor type 11a.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
ENSPKIP00000007905	LOC111855741	ENSPKIP00000007905	ENSPKIP00000023211	Protein tyrosine phosphatase non-receptor type 11a.	Tyrosine-protein kinase.	0.538
ENSPKIP00000009283	atp6ap1	ENSPKIP00000009283	ENSPKIP00000022161	ATPase H+ transporting accessory protein 1a.	ATPase H+ transporting accessory protein 1b.	0.902
ENSPKIP00000040839	Gp1bb	ENSPKIP00000040839	ENSPKIP00000009618	Glycoprotein IX (platelet).	Glycoprotein Ib platelet subunit beta.	0.907
EP300	LOC111845232	ENSPKIP00000027655	ENSPKIP00000018215	E1A binding protein p300.	Uncharacterized protein.	0.901
EP300	Med1	ENSPKIP00000027655	ENSPKIP00000002844	E1A binding protein p300.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.728
EP300	fam20c	ENSPKIP00000027655	ENSPKIP00000017233	E1A binding protein p300.	FAM20C golgi associated secretory pathway kinase b.	0.402
Gp1bb	ENSPKIP00000040839	ENSPKIP00000009618	ENSPKIP00000040839	Glycoprotein Ib platelet subunit beta.	Glycoprotein IX (platelet).	0.907
LOC111835754	LOC111836858	ENSPKIP00000006616	ENSPKIP00000039545	Serum response factor b.	Serum response factor a.	0.902
LOC111835923	ENSPKIP00000007905	ENSPKIP00000017997	ENSPKIP00000007905	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 11a.	0.538
LOC111835923	LOC111850568	ENSPKIP00000017997	ENSPKIP00000007894	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.538
LOC111835923	LOC111853334	ENSPKIP00000017997	ENSPKIP00000013653	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.538
LOC111835923	LOC111855741	ENSPKIP00000017997	ENSPKIP00000023211	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC111835923	ptpn6	ENSPKIP00000017997	ENSPKIP00000025032	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.477
LOC111836858	LOC111835754	ENSPKIP00000039545	ENSPKIP00000006616	Serum response factor a.	Serum response factor b.	0.902
LOC111845232	EP300	ENSPKIP00000018215	ENSPKIP00000027655	Uncharacterized protein.	E1A binding protein p300.	0.901
LOC111845232	Med1	ENSPKIP00000018215	ENSPKIP00000002844	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.728
LOC111845232	fam20c	ENSPKIP00000018215	ENSPKIP00000017233	Uncharacterized protein.	FAM20C golgi associated secretory pathway kinase b.	0.402