STRINGSTRING
polr2b polr2b gtf2h1 gtf2h1 LOC111860656 LOC111860656 ncbp2 ncbp2 LOC111860494 LOC111860494 gtf2h5 gtf2h5 polr2i polr2i polr2h polr2h ENSPKIP00000008065 ENSPKIP00000008065 mnat1 mnat1 Polr2l Polr2l ENSPKIP00000039783 ENSPKIP00000039783 cdk7 cdk7 NCBP1 NCBP1 ENSPKIP00000036923 ENSPKIP00000036923 gtf2h2c gtf2h2c LOC111843713 LOC111843713 Gtf2f2 Gtf2f2 polr2j polr2j polr2d polr2d nelfe nelfe gtf2h4 gtf2h4 ENSPKIP00000030381 ENSPKIP00000030381 ENSPKIP00000030006 ENSPKIP00000030006 LOC111836620 LOC111836620 ENSPKIP00000024903 ENSPKIP00000024903 ercc2 ercc2 supt5h supt5h ENSPKIP00000021454 ENSPKIP00000021454 ENSPKIP00000021292 ENSPKIP00000021292 polr2c polr2c gtf2f1 gtf2f1 nelfcd nelfcd ctdp1 ctdp1 polr2f polr2f ccnh ccnh ercc3 ercc3 Polr2g Polr2g nelfb nelfb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1231 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (544 aa)
LOC111860656Si:dkey-12j5.1. (398 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
LOC111860494RNA polymerase II subunit E. (210 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSPKIP00000008065General transcription factor IIH, polypeptide 3. (293 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (315 aa)
Polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (80 aa)
ENSPKIP00000039783Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (109 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (348 aa)
NCBP1Nuclear cap binding protein subunit 1. (794 aa)
ENSPKIP00000036923Negative elongation factor complex member A. (568 aa)
gtf2h2cGeneral transcription factor IIH subunit. (407 aa)
LOC111843713Si:dkeyp-115e12.6. (2067 aa)
Gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (276 aa)
polr2jRNA_pol_L_2 domain-containing protein. (145 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
nelfeNegative elongation factor complex member E. (374 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
ENSPKIP00000030381Uncharacterized protein. (281 aa)
ENSPKIP00000030006Uncharacterized protein. (127 aa)
LOC111836620RNA polymerase II subunit E. (222 aa)
ENSPKIP00000024903Uncharacterized protein. (319 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
supt5hTranscription elongation factor SPT5. (1083 aa)
ENSPKIP00000021454Uncharacterized protein. (67 aa)
ENSPKIP00000021292DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1851 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (534 aa)
nelfcdNegative elongation factor complex member C/D. (579 aa)
ctdp1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (966 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
ccnhCyclin H; Belongs to the cyclin family. (325 aa)
ercc3Excision repair cross-complementation group 3. (786 aa)
Polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (198 aa)
nelfbNegative elongation factor complex member B. (583 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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