STRINGSTRING
LOC111840348 LOC111840348 ENSPKIP00000000040 ENSPKIP00000000040 ENSPKIP00000000180 ENSPKIP00000000180 LOC111850762 LOC111850762 UBB UBB EZH1 EZH1 ENSPKIP00000000927 ENSPKIP00000000927 LOC111852944 LOC111852944 map3k5 map3k5 LOC111844425 LOC111844425 ENSPKIP00000002266 ENSPKIP00000002266 ENSPKIP00000002486 ENSPKIP00000002486 LOC111838709 LOC111838709 ENSPKIP00000003094 ENSPKIP00000003094 ENSPKIP00000003127 ENSPKIP00000003127 LOC111850490 LOC111850490 LOC111835014 LOC111835014 ENSPKIP00000003264 ENSPKIP00000003264 ENSPKIP00000003332 ENSPKIP00000003332 ENSPKIP00000003502 ENSPKIP00000003502 LOC111855469 LOC111855469 ENSPKIP00000003555 ENSPKIP00000003555 ENSPKIP00000003629 ENSPKIP00000003629 ENSPKIP00000003747 ENSPKIP00000003747 ENSPKIP00000003821 ENSPKIP00000003821 ENSPKIP00000003984 ENSPKIP00000003984 ENSPKIP00000004039 ENSPKIP00000004039 ENSPKIP00000004111 ENSPKIP00000004111 SCMH1 SCMH1 rps27a rps27a scml2 scml2 LOC111836901 LOC111836901 LOC111844443 LOC111844443 LOC111841927 LOC111841927 mdm2 mdm2 fosl2 fosl2 LOC111841927-2 LOC111841927-2 mapkapk5 mapkapk5 ENSPKIP00000007452 ENSPKIP00000007452 LOC111837588 LOC111837588 RING1 RING1 LOC111839372 LOC111839372 MAPK14 MAPK14 LOC111839418 LOC111839418 rbbp4 rbbp4 ENSPKIP00000010023 ENSPKIP00000010023 ENSPKIP00000010346 ENSPKIP00000010346 phc1 phc1 LOC111840606 LOC111840606 eed eed LOC111841927-3 LOC111841927-3 H2AZ1 H2AZ1 EZH1-2 EZH1-2 KDM6B KDM6B cdk6 cdk6 ENSPKIP00000013558 ENSPKIP00000013558 LOC111846417 LOC111846417 EZH2 EZH2 ENSPKIP00000014030 ENSPKIP00000014030 ENSPKIP00000014072 ENSPKIP00000014072 EZH2-2 EZH2-2 tp53 tp53 ENSPKIP00000015244 ENSPKIP00000015244 LOC111835825 LOC111835825 FOS FOS LOC111852373 LOC111852373 ENSPKIP00000016841 ENSPKIP00000016841 MAP2K4 MAP2K4 nptx2 nptx2 ENSPKIP00000018067 ENSPKIP00000018067 ENSPKIP00000018340 ENSPKIP00000018340 cbx7 cbx7 nptxr nptxr LOC111845190 LOC111845190 ENSPKIP00000018762 ENSPKIP00000018762 ENSPKIP00000018854 ENSPKIP00000018854 cbx4 cbx4 cbx8 cbx8 mapkapk2 mapkapk2 LOC111833559 LOC111833559 ENSPKIP00000019966 ENSPKIP00000019966 LOC111845939 LOC111845939 ENSPKIP00000020639 ENSPKIP00000020639 LOC111854492 LOC111854492 cdk4 cdk4 rnf2 rnf2 ENSPKIP00000021572 ENSPKIP00000021572 ENSPKIP00000022413 ENSPKIP00000022413 ENSPKIP00000023005 ENSPKIP00000023005 LOC111841927-4 LOC111841927-4 mapk10 mapk10 Cdkn2c Cdkn2c map2k7 map2k7 CDKN2D CDKN2D LOC111835993 LOC111835993 ENSPKIP00000025247 ENSPKIP00000025247 LOC111843316 LOC111843316 MAP2K3 MAP2K3 LOC111851441 LOC111851441 ENSPKIP00000027496 ENSPKIP00000027496 LOC111833605 LOC111833605 LOC111837856 LOC111837856 ENSPKIP00000030577 ENSPKIP00000030577 ENSPKIP00000030657 ENSPKIP00000030657 H2BC8 H2BC8 ENSPKIP00000030772 ENSPKIP00000030772 ENSPKIP00000031300 ENSPKIP00000031300 mdm4 mdm4 MAPKAPK2 MAPKAPK2 mapk1 mapk1 LOC111850265 LOC111850265 ENSPKIP00000033989 ENSPKIP00000033989 LOC111859759 LOC111859759 LOC111855945 LOC111855945 Map2k6 Map2k6 ENSPKIP00000035835 ENSPKIP00000035835 ENSPKIP00000037150 ENSPKIP00000037150 ENSPKIP00000038374 ENSPKIP00000038374 ENSPKIP00000038408 ENSPKIP00000038408 ENSPKIP00000038497 ENSPKIP00000038497 ENSPKIP00000038535 ENSPKIP00000038535 ENSPKIP00000038554 ENSPKIP00000038554 txn txn LOC111848368 LOC111848368 MAPK8 MAPK8 LOC111835041 LOC111835041 LOC111859259 LOC111859259 LOC111842968 LOC111842968 LOC111855955 LOC111855955 LOC111845666 LOC111845666 TNIK TNIK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111840348Mitogen-activated protein kinase. (359 aa)
ENSPKIP00000000040Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSPKIP00000000180BZIP domain-containing protein. (393 aa)
LOC111850762Mitogen-activated protein kinase. (419 aa)
UBBUbiquitin B. (230 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (800 aa)
ENSPKIP00000000927Mitogen-activated protein kinase kinase kinase kinase 4. (1291 aa)
LOC111852944Lysine (K)-specific demethylase 6B, b. (1873 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1396 aa)
LOC111844425Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSPKIP00000002266Histone H3; Belongs to the histone H3 family. (97 aa)
ENSPKIP00000002486Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC111838709Histone H3; Belongs to the histone H3 family. (136 aa)
ENSPKIP00000003094Histone H2B; Belongs to the histone H2B family. (116 aa)
ENSPKIP00000003127Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
LOC111850490TRAF2 and NCK interacting kinase a. (1334 aa)
LOC111835014Si:zfos-2326c3.2. (1212 aa)
ENSPKIP00000003264Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSPKIP00000003332Histone H3; Belongs to the histone H3 family. (99 aa)
ENSPKIP00000003502Histone domain-containing protein. (89 aa)
LOC111855469Mitogen-activated protein kinase. (422 aa)
ENSPKIP00000003555Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSPKIP00000003629Histone H2B; Belongs to the histone H2B family. (164 aa)
ENSPKIP00000003747Histone H3; Belongs to the histone H3 family. (97 aa)
ENSPKIP00000003821Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSPKIP00000003984Histone H2A; Belongs to the histone H2A family. (137 aa)
ENSPKIP00000004039Histone H2B; Belongs to the histone H2B family. (67 aa)
ENSPKIP00000004111Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (86 aa)
SCMH1Scm polycomb group protein homolog 1. (718 aa)
rps27aRibosomal protein S27a. (156 aa)
scml2Scm polycomb group protein like 2. (714 aa)
LOC111836901Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
LOC111844443BZIP domain-containing protein. (369 aa)
LOC111841927Histone H3; Belongs to the histone H3 family. (136 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (458 aa)
fosl2Fos-like antigen 2. (335 aa)
LOC111841927-2Histone H3.3. (136 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
ENSPKIP00000007452Uncharacterized protein. (201 aa)
LOC111837588MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (403 aa)
RING1Ring finger protein 1. (365 aa)
LOC111839372Mitogen-activated protein kinase. (426 aa)
MAPK14Mitogen-activated protein kinase. (362 aa)
LOC111839418BZIP domain-containing protein. (326 aa)
rbbp4Retinoblastoma binding protein 4. (424 aa)
ENSPKIP00000010023Histone H3; Belongs to the histone H3 family. (138 aa)
ENSPKIP00000010346Uncharacterized protein. (511 aa)
phc1Polyhomeotic homolog 1. (914 aa)
LOC111840606MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (409 aa)
eedEmbryonic ectoderm development. (441 aa)
LOC111841927-3Histone H3.3. (136 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
EZH1-2Enhancer of zeste 1 polycomb repressive complex 2 subunit. (745 aa)
KDM6BLysine (K)-specific demethylase 6B, a. (1844 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (321 aa)
ENSPKIP00000013558Uncharacterized protein. (308 aa)
LOC111846417Chromo domain-containing protein. (418 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (725 aa)
ENSPKIP00000014030Uncharacterized protein. (514 aa)
ENSPKIP00000014072Chromobox homolog 6b. (552 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (766 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (431 aa)
ENSPKIP00000015244Histone domain-containing protein. (169 aa)
LOC111835825Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (378 aa)
LOC111852373V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (382 aa)
ENSPKIP00000016841Histone H2A; Belongs to the histone H2A family. (186 aa)
MAP2K4Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (449 aa)
nptx2Uncharacterized protein. (440 aa)
ENSPKIP00000018067Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
ENSPKIP00000018340Histone H2B; Belongs to the histone H2B family. (108 aa)
cbx7Chromobox homolog 7b. (260 aa)
nptxrNeuronal pentraxin receptor b. (523 aa)
LOC111845190Chromo domain-containing protein. (526 aa)
ENSPKIP00000018762Histone H2A; Belongs to the histone H2A family. (141 aa)
ENSPKIP00000018854BZIP domain-containing protein; Belongs to the bZIP family. (285 aa)
cbx4Chromobox homolog 4 (Pc class homolog, Drosophila). (538 aa)
cbx8Chromobox homolog 8b. (351 aa)
mapkapk2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
LOC111833559SUZ12 polycomb repressive complex 2 subunit. (646 aa)
ENSPKIP00000019966Misshapen-like kinase 1. (1248 aa)
LOC111845939Histone H2B; Belongs to the histone H2B family. (117 aa)
ENSPKIP00000020639Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (406 aa)
LOC111854492Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (441 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (298 aa)
rnf2Ring finger protein 2. (342 aa)
ENSPKIP00000021572Uncharacterized protein. (278 aa)
ENSPKIP00000022413VEFS-Box domain-containing protein. (668 aa)
ENSPKIP00000023005Bmi1 polycomb ring finger oncogene 1b. (389 aa)
LOC111841927-4Histone H3.3. (136 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
Cdkn2cCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (164 aa)
map2k7Mitogen-activated protein kinase kinase 7. (438 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
LOC111835993Mitogen-activated protein kinase. (388 aa)
ENSPKIP00000025247Histone H2A; Belongs to the histone H2A family. (141 aa)
LOC111843316Chromobox homolog 8a (Pc class homolog, Drosophila). (383 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
LOC111851441Histone H2A; Belongs to the histone H2A family. (142 aa)
ENSPKIP00000027496Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (319 aa)
LOC111833605Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (174 aa)
LOC111837856RING-type domain-containing protein. (328 aa)
ENSPKIP00000030577Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSPKIP00000030657Histone H3; Belongs to the histone H3 family. (98 aa)
H2BC8Histone domain-containing protein; Belongs to the histone H2B family. (117 aa)
ENSPKIP00000030772Histone H3; Belongs to the histone H3 family. (98 aa)
ENSPKIP00000031300Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (127 aa)
mdm4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (486 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC111850265Scm polycomb group protein like 2. (691 aa)
ENSPKIP00000033989Retinoblastoma binding protein 4, like. (469 aa)
LOC111859759Protein kinase domain-containing protein. (398 aa)
LOC111855945Chromobox homolog 2 (Drosophila Pc class). (537 aa)
Map2k6Mitogen-activated protein kinase kinase 6. (398 aa)
ENSPKIP00000035835BZIP domain-containing protein. (326 aa)
ENSPKIP00000037150Thioredoxin domain-containing protein. (240 aa)
ENSPKIP00000038374Histone H2B; Belongs to the histone H2B family. (118 aa)
ENSPKIP00000038408Histone H2B; Belongs to the histone H2B family. (203 aa)
ENSPKIP00000038497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSPKIP00000038535Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
ENSPKIP00000038554Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
txnThioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC111848368Mitogen-activated protein kinase. (434 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC111835041Uncharacterized protein. (1299 aa)
LOC111859259ANK_REP_REGION domain-containing protein. (126 aa)
LOC111842968NME/NM23 family member 8; Belongs to the NDK family. (617 aa)
LOC111855955Neuronal pentraxin 2. (441 aa)
LOC111845666Mitogen-activated protein kinase. (361 aa)
TNIKTRAF2 and NCK interacting kinase. (1207 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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