STRINGSTRING
ENSPKIP00000000040 ENSPKIP00000000040 ENSPKIP00000030772 ENSPKIP00000030772 orc1 orc1 LOC111836635 LOC111836635 ube2s ube2s LOC111842809 LOC111842809 psma4 psma4 psmd4 psmd4 psmd14 psmd14 PSMD2 PSMD2 Bicra Bicra LOC111856488 LOC111856488 psmd8 psmd8 psmc3 psmc3 psmc4 psmc4 mcm9 mcm9 PSMB5 PSMB5 psma3 psma3 Psme2 Psme2 LOC111834296 LOC111834296 mcm8 mcm8 fam89a fam89a anapc10 anapc10 ENSPKIP00000038374 ENSPKIP00000038374 ENSPKIP00000038408 ENSPKIP00000038408 ENSPKIP00000038497 ENSPKIP00000038497 ENSPKIP00000038535 ENSPKIP00000038535 ENSPKIP00000038554 ENSPKIP00000038554 fzr1 fzr1 orc3 orc3 Psmc5 Psmc5 BICRA BICRA Cdc26 Cdc26 anapc2 anapc2 kpnb1 kpnb1 ENSPKIP00000003502 ENSPKIP00000003502 ENSPKIP00000003332 ENSPKIP00000003332 ENSPKIP00000003264 ENSPKIP00000003264 cdc23 cdc23 ENSPKIP00000003127 ENSPKIP00000003127 ENSPKIP00000003094 ENSPKIP00000003094 ENSPKIP00000002857 ENSPKIP00000002857 LOC111838709 LOC111838709 mcm7 mcm7 ube2c ube2c psmd13 psmd13 ENSPKIP00000016841 ENSPKIP00000016841 ENSPKIP00000002486 ENSPKIP00000002486 ENSPKIP00000002266 ENSPKIP00000002266 LOC111844425 LOC111844425 ENSPKIP00000000850 ENSPKIP00000000850 LOC111835646 LOC111835646 ENSPKIP00000000773 ENSPKIP00000000773 LOC111835645 LOC111835645 UBB UBB H2BC8 H2BC8 ENSPKIP00000030657 ENSPKIP00000030657 ENSPKIP00000030577 ENSPKIP00000030577 mcm6 mcm6 LOC111839057 LOC111839057 ENSPKIP00000028977 ENSPKIP00000028977 LOC111854587 LOC111854587 UBE2E1 UBE2E1 LOC111851430 LOC111851430 LOC111851441 LOC111851441 PSMC1 PSMC1 cdt1 cdt1 ENSPKIP00000025247 ENSPKIP00000025247 psmb1 psmb1 psme1 psme1 psmb7 psmb7 LOC111850128 LOC111850128 anapc16 anapc16 psmb3 psmb3 anapc7 anapc7 LOC111841927-4 LOC111841927-4 psmc2 psmc2 ENSPKIP00000022716 ENSPKIP00000022716 gmnn gmnn psmd12 psmd12 Anapc11 Anapc11 uba52 uba52 psmb6 psmb6 psmf1 psmf1 ENSPKIP00000020772 ENSPKIP00000020772 LOC111845939 LOC111845939 orc6 orc6 psma5 psma5 LOC111860090 LOC111860090 psmd5 psmd5 ENSPKIP00000018762 ENSPKIP00000018762 Anapc4 Anapc4 ENSPKIP00000018473 ENSPKIP00000018473 ENSPKIP00000018340 ENSPKIP00000018340 ENSPKIP00000018067 ENSPKIP00000018067 cdc16 cdc16 orc2 orc2 orc4 orc4 BICRAL BICRAL kxd1 kxd1 mcm2 mcm2 Kpna6 Kpna6 LOC111852026 LOC111852026 PSMD6 PSMD6 psmb4 psmb4 ENSPKIP00000010023 ENSPKIP00000010023 kpna1 kpna1 tm7sf3 tm7sf3 psma2 psma2 kpna5 kpna5 orc5 orc5 LOC111841927-3 LOC111841927-3 LOC111854942 LOC111854942 H2AZ1 H2AZ1 psmd11 psmd11 LOC111834000 LOC111834000 Psme3 Psme3 psmd7 psmd7 ENSPKIP00000015244 ENSPKIP00000015244 psmd1 psmd1 mcm4 mcm4 psmd9 psmd9 cdc27 cdc27 LOC111857400 LOC111857400 psma1 psma1 anapc5 anapc5 psmd6 psmd6 LOC111841927-2 LOC111841927-2 cdc6 cdc6 anapc15 anapc15 LOC111841780 LOC111841780 psma6 psma6 psmb2 psmb2 LOC111848642 LOC111848642 LOC111841927 LOC111841927 psmc6 psmc6 mcm3 mcm3 Psmd10 Psmd10 rps27a rps27a ENSPKIP00000004111 ENSPKIP00000004111 ENSPKIP00000004039 ENSPKIP00000004039 ENSPKIP00000003984 ENSPKIP00000003984 ENSPKIP00000003821 ENSPKIP00000003821 ENSPKIP00000003747 ENSPKIP00000003747 anapc1 anapc1 ENSPKIP00000003629 ENSPKIP00000003629 ENSPKIP00000003555 ENSPKIP00000003555
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPKIP00000000040Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSPKIP00000030772Histone H3; Belongs to the histone H3 family. (98 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (909 aa)
LOC11183663526S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (232 aa)
LOC111842809Proteasome subunit beta. (278 aa)
psma4Proteasome subunit alpha type. (261 aa)
psmd4Proteasome 26S subunit, non-ATPase 4a. (378 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (932 aa)
BicraBRD4 interacting chromatin remodeling complex associated protein. (1658 aa)
LOC111856488Ubiquitin-like domain-containing protein. (95 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (267 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (481 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1146 aa)
PSMB5Proteasome subunit beta 5. (292 aa)
psma3Proteasome subunit alpha type. (255 aa)
Psme2Proteasome activator subunit 2. (248 aa)
LOC111834296PCI domain-containing protein. (382 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (866 aa)
fam89aFamily with sequence similarity 89 member A. (195 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ENSPKIP00000038374Histone H2B; Belongs to the histone H2B family. (118 aa)
ENSPKIP00000038408Histone H2B; Belongs to the histone H2B family. (203 aa)
ENSPKIP00000038497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSPKIP00000038535Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
ENSPKIP00000038554Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
fzr1Fizzy/cell division cycle 20 related 1a. (495 aa)
orc3Origin recognition complex, subunit 3. (723 aa)
Psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (413 aa)
BICRABRD4 interacting chromatin remodeling complex associated protein. (1797 aa)
Cdc26Cell division cycle 26 homolog. (135 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (801 aa)
kpnb1Karyopherin (importin) beta 1. (877 aa)
ENSPKIP00000003502Histone domain-containing protein. (89 aa)
ENSPKIP00000003332Histone H3; Belongs to the histone H3 family. (99 aa)
ENSPKIP00000003264Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (578 aa)
ENSPKIP00000003127Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSPKIP00000003094Histone H2B; Belongs to the histone H2B family. (116 aa)
ENSPKIP00000002857Uncharacterized protein. (344 aa)
LOC111838709Histone H3; Belongs to the histone H3 family. (136 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (187 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
ENSPKIP00000016841Histone H2A; Belongs to the histone H2A family. (186 aa)
ENSPKIP00000002486Histone H2A; Belongs to the histone H2A family. (131 aa)
ENSPKIP00000002266Histone H3; Belongs to the histone H3 family. (97 aa)
LOC111844425Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSPKIP00000000850Proteasome subunit beta. (225 aa)
LOC111835646Proteasome subunit beta 12. (211 aa)
ENSPKIP00000000773Proteasome subunit beta 13a. (263 aa)
LOC111835645Proteasome subunit beta. (275 aa)
UBBUbiquitin B. (230 aa)
H2BC8Histone domain-containing protein; Belongs to the histone H2B family. (117 aa)
ENSPKIP00000030657Histone H3; Belongs to the histone H3 family. (98 aa)
ENSPKIP00000030577Histone H2B; Belongs to the histone H2B family. (113 aa)
mcm6DNA helicase; Belongs to the MCM family. (815 aa)
LOC111839057UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
ENSPKIP00000028977Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC111854587Proteasome subunit beta. (299 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
LOC111851430Ubiquitin-like domain-containing protein. (77 aa)
LOC111851441Histone H2A; Belongs to the histone H2A family. (142 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
cdt1Chromatin licensing and DNA replication factor 1. (655 aa)
ENSPKIP00000025247Histone H2A; Belongs to the histone H2A family. (141 aa)
psmb1Proteasome subunit beta. (237 aa)
psme1Proteasome activator subunit 1. (254 aa)
psmb7Proteasome subunit beta. (277 aa)
LOC111850128DNA helicase; Belongs to the MCM family. (806 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
psmb3Proteasome subunit beta. (238 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
LOC111841927-4Histone H3.3. (136 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
ENSPKIP00000022716DNA helicase; Belongs to the MCM family. (664 aa)
gmnnGeminin DNA replication inhibitor. (230 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
Anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (86 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
psmb6Proteasome subunit beta. (231 aa)
psmf1Proteasome inhibitor subunit 1. (269 aa)
ENSPKIP00000020772Fizzy/cell division cycle 20 related 1b. (515 aa)
LOC111845939Histone H2B; Belongs to the histone H2B family. (117 aa)
orc6Origin recognition complex, subunit 6. (277 aa)
psma5Proteasome subunit alpha type. (262 aa)
LOC111860090Family with sequence similarity 89 member B. (189 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
ENSPKIP00000018762Histone H2A; Belongs to the histone H2A family. (141 aa)
Anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (774 aa)
ENSPKIP00000018473ANAPC4_WD40 domain-containing protein. (80 aa)
ENSPKIP00000018340Histone H2B; Belongs to the histone H2B family. (108 aa)
ENSPKIP00000018067Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (617 aa)
orc2Origin recognition complex, subunit 2. (541 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (479 aa)
BICRALBRD4 interacting chromatin remodeling complex associated protein like. (898 aa)
kxd1KxDL motif containing 1. (178 aa)
mcm2DNA helicase; Belongs to the MCM family. (899 aa)
Kpna6Importin subunit alpha; Belongs to the importin alpha family. (525 aa)
LOC111852026Proteasome subunit alpha type. (234 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa)
ENSPKIP00000010023Histone H3; Belongs to the histone H3 family. (138 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (569 aa)
tm7sf3Transmembrane 7 superfamily member 3. (564 aa)
psma2Proteasome subunit alpha type. (234 aa)
kpna5Importin subunit alpha; Belongs to the importin alpha family. (539 aa)
orc5Origin recognition complex, subunit 5. (443 aa)
LOC111841927-3Histone H3.3. (136 aa)
LOC111854942Proteasome subunit alpha type. (246 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
psmd11Proteasome 26S subunit, non-ATPase 11b. (421 aa)
LOC111834000DNA helicase; Belongs to the MCM family. (815 aa)
Psme3Proteasome activator subunit 3. (255 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (326 aa)
ENSPKIP00000015244Histone domain-containing protein. (169 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (962 aa)
mcm4DNA helicase; Belongs to the MCM family. (861 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (215 aa)
cdc27Cell division cycle 27. (833 aa)
LOC111857400DUF4203 domain-containing protein. (546 aa)
psma1Proteasome subunit alpha type. (262 aa)
anapc5Anaphase promoting complex subunit 5. (767 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (436 aa)
LOC111841927-2Histone H3.3. (136 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
anapc15Anaphase promoting complex subunit 15. (121 aa)
LOC111841780AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
psma6Proteasome subunit alpha type. (248 aa)
psmb2Proteasome subunit beta. (199 aa)
LOC111848642Proteasome 26S subunit, non-ATPase 3. (523 aa)
LOC111841927Histone H3; Belongs to the histone H3 family. (136 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
mcm3DNA helicase; Belongs to the MCM family. (808 aa)
Psmd10Proteasome 26S subunit, non-ATPase 10. (252 aa)
rps27aRibosomal protein S27a. (156 aa)
ENSPKIP00000004111Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (86 aa)
ENSPKIP00000004039Histone H2B; Belongs to the histone H2B family. (67 aa)
ENSPKIP00000003984Histone H2A; Belongs to the histone H2A family. (137 aa)
ENSPKIP00000003821Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSPKIP00000003747Histone H3; Belongs to the histone H3 family. (97 aa)
anapc1Anaphase promoting complex subunit 1. (1967 aa)
ENSPKIP00000003629Histone H2B; Belongs to the histone H2B family. (164 aa)
ENSPKIP00000003555Histone H2A; Belongs to the histone H2A family. (129 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
Server load: low (18%) [HD]