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| | tert | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1052 aa) |
| | mis18a | MIS18 kinetochore protein A. (224 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (418 aa) |
| | mis18bp1 | Myb-like domain-containing protein. (1328 aa) |
| | ppp6c | Serine/threonine-protein phosphatase. (305 aa) |
| | LOC111838675 | Nucleophosmin 1a. (301 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1325 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (461 aa) |
| | ENSPKIP00000009032 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa) |
| | LOC111842662 | Remodeling and spacing factor 1b, tandem duplicate 1. (2102 aa) |
| | rbbp4 | Retinoblastoma binding protein 4. (424 aa) |
| | ENSPKIP00000010323 | DNA polymerase. (1377 aa) |
| | cenpp | Centromere protein P. (284 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | ENSPKIP00000011013 | WRN RecQ like helicase. (1122 aa) |
| | ENSPKIP00000011404 | Polymerase (DNA-directed), delta 3, accessory subunit. (395 aa) |
| | LOC111859308 | TERF1 (TRF1)-interacting nuclear factor 2. (560 aa) |
| | ANKRD28 | Ankyrin repeat domain 28b. (1004 aa) |
| | H2AZ1 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | cenpn | Centromere protein N. (344 aa) |
| | stn1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa) |
| | ankrd44 | Ankyrin repeat domain 44. (1017 aa) |
| | wrap53 | WD repeat containing, antisense to TP53. (536 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | cenpi | Centromere protein I. (738 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa) |
| | cenpk | Centromere protein K. (286 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (468 aa) |
| | cenpt | Uncharacterized protein. (925 aa) |
| | cenpm | Proliferation associated nuclear element. (185 aa) |
| | ENSPKIP00000016002 | Uncharacterized protein. (385 aa) |
| | LOC111856243 | Mis18 domain-containing protein. (238 aa) |
| | ENSPKIP00000016841 | Histone H2A; Belongs to the histone H2A family. (186 aa) |
| | Knl1 | Knl1_RWD_C domain-containing protein. (2068 aa) |
| | ENSPKIP00000018067 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa) |
| | ENSPKIP00000018158 | Uncharacterized protein. (112 aa) |
| | Trub1 | TruB pseudouridine (psi) synthase family member 1. (231 aa) |
| | ENSPKIP00000018340 | Histone H2B; Belongs to the histone H2B family. (108 aa) |
| | ENSPKIP00000018762 | Histone H2A; Belongs to the histone H2A family. (141 aa) |
| | rfc1 | Replication factor C subunit 1. (1155 aa) |
| | rpa2 | Replication protein A2. (339 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | LOC111845939 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | LOC111834097 | Zgc:110269. (346 aa) |
| | LOC111856291 | ANK_REP_REGION domain-containing protein. (170 aa) |
| | terf2 | Telomeric repeat binding factor 2. (563 aa) |
| | nhp2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa) |
| | terf1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (441 aa) |
| | ENSPKIP00000023299 | TEN1 subunit of CST complex. (131 aa) |
| | LOC111859009 | Serine/threonine-protein phosphatase. (305 aa) |
| | Exd2 | Exonuclease 3'-5' domain containing 2. (630 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | ENSPKIP00000025247 | Histone H2A; Belongs to the histone H2A family. (141 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1345 aa) |
| | Dkc1 | Dyskeratosis congenita 1, dyskerin. (565 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | ENSPKIP00000000040 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | LOC111861157 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | cenph | Centromere protein H. (237 aa) |
| | Gar1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (223 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (604 aa) |
| | dscc1 | DNA replication and sister chromatid cohesion 1. (394 aa) |
| | ENSPKIP00000000392 | AAA domain-containing protein. (944 aa) |
| | daxx | Death-domain associated protein. (737 aa) |
| | cenpw | Si:ch211-195p4.4. (75 aa) |
| | LOC111859352 | Nucleophosmin 1b. (309 aa) |
| | LOC111844425 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC111851441 | Histone H2A; Belongs to the histone H2A family. (142 aa) |
| | recql4 | RecQ helicase-like 4. (1512 aa) |
| | ENSPKIP00000002486 | Histone H2A; Belongs to the histone H2A family. (131 aa) |
| | LOC111859367 | Uncharacterized protein. (545 aa) |
| | ENSPKIP00000003094 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | ENSPKIP00000003127 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSPKIP00000003264 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSPKIP00000003555 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | ENSPKIP00000003629 | Histone H2B; Belongs to the histone H2B family. (164 aa) |
| | ENSPKIP00000003821 | Histone H2A; Belongs to the histone H2A family. (127 aa) |
| | ENSPKIP00000003984 | Histone H2A; Belongs to the histone H2A family. (137 aa) |
| | ENSPKIP00000004039 | Histone H2B; Belongs to the histone H2B family. (67 aa) |
| | ENSPKIP00000004111 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (86 aa) |
| | shq1 | SHQ1, H/ACA ribonucleoprotein assembly factor. (563 aa) |
| | ctc1 | Uncharacterized protein. (1337 aa) |
| | LOC111858065 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (618 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (155 aa) |
| | atrx | ATRX chromatin remodeler. (2165 aa) |
| | ENSPKIP00000032000 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (612 aa) |
| | LOC111842731 | Selenoprotein H. (176 aa) |
| | cenpq | Uncharacterized protein. (273 aa) |
| | LOC111840361 | RNA binding protein, mRNA processing factor 2b. (196 aa) |
| | LOC111843688 | BTB domain-containing protein. (532 aa) |
| | ENSPKIP00000033989 | Retinoblastoma binding protein 4, like. (469 aa) |
| | ENSPKIP00000034087 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (983 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (417 aa) |
| | ENSPKIP00000035383 | PHD-type domain-containing protein. (714 aa) |
| | Pold4 | Si:dkey-28b4.7. (121 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (351 aa) |
| | ANKRD66 | Ankyrin repeat domain 66. (198 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1025 aa) |
| | SMARCA5-2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1024 aa) |
| | Lig1 | DNA ligase. (964 aa) |
| | ENSPKIP00000038374 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | ENSPKIP00000038408 | Histone H2B; Belongs to the histone H2B family. (203 aa) |
| | ENSPKIP00000038497 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa) |
| | ENSPKIP00000038535 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa) |
| | ENSPKIP00000038554 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC111840311 | Ankyrin repeat domain 52a. (1072 aa) |
| | cenpo | Centromere protein O. (293 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (464 aa) |
| | ANKRD28-2 | Ankyrin repeat domain 28b. (1061 aa) |
| | pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (716 aa) |
| | blm | BLM RecQ like helicase. (1442 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (336 aa) |
| | LOC111851480 | Nucleophosmin/nucleoplasmin, 2b. (197 aa) |
| | cenpl | Centromere protein L. (343 aa) |
| | rpa3 | Replication protein A3. (123 aa) |
| | Terf2ip | Uncharacterized protein. (550 aa) |
| | ENSPKIP00000030577 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | nop10 | NOP10 ribonucleoprotein homolog (yeast). (64 aa) |
| | H2BC8 | Histone domain-containing protein; Belongs to the histone H2B family. (117 aa) |
| | ENSPKIP00000030825 | Telo_bind domain-containing protein. (703 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1206 aa) |
| | CENPS | Centromere protein S. (144 aa) |
