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LOC111857269 LOC111857269 sucla2 sucla2 sdhd sdhd ACLY ACLY IDH2 IDH2 idh2 idh2 suclg2 suclg2 aco1 aco1 sdha sdha pc pc pdhb pdhb idh3a idh3a fh fh LOC111842517 LOC111842517 sdhb sdhb OGDH OGDH ENSPKIP00000016972 ENSPKIP00000016972 dlst dlst LOC111855058 LOC111855058 pck1 pck1 MDH1 MDH1 LOC111855770 LOC111855770 LOC111853220 LOC111853220 ENSPKIP00000026650 ENSPKIP00000026650 dlat dlat suclg1 suclg1 mdh2 mdh2 idh1 idh1 dld dld sdhc sdhc LOC111855268 LOC111855268 idh3b idh3b CS CS PCK2 PCK2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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LOC111857269Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (461 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (182 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1092 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (433 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (894 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (662 aa)
pcUncharacterized protein. (1240 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
fhFumarate hydratase. (506 aa)
LOC111842517ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1120 aa)
sdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (281 aa)
OGDHOxoglutarate dehydrogenase. (1052 aa)
ENSPKIP00000016972Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (759 aa)
dlstDihydrolipoamide S-succinyltransferase. (464 aa)
LOC111855058Citrate synthase; Belongs to the citrate synthase family. (468 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
MDH1Malate dehydrogenase. (350 aa)
LOC111855770Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
LOC111853220Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
ENSPKIP00000026650Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1017 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (645 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
mdh2Malate dehydrogenase. (336 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (169 aa)
LOC111855268Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (397 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (419 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (468 aa)
PCK2Uncharacterized protein. (634 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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