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hsd17b7 hsd17b7 SRD5A2 SRD5A2 hsd17b1 hsd17b1 LOC111847995 LOC111847995 hsd17b8 hsd17b8 ENSPKIP00000002284 ENSPKIP00000002284 ENSPKIP00000002931 ENSPKIP00000002931 ENSPKIP00000003742 ENSPKIP00000003742 Hsd17b12 Hsd17b12 AKR1D1 AKR1D1 LOC111848628 LOC111848628 ENSPKIP00000006910 ENSPKIP00000006910 comt comt srd5a1 srd5a1 LOC111835705 LOC111835705 LOC111839405 LOC111839405 LOC111842469 LOC111842469 LOC111845911 LOC111845911 LOC111836781 LOC111836781 ENSPKIP00000014924 ENSPKIP00000014924 srd5a3 srd5a3 LOC111848196 LOC111848196 ENSPKIP00000021171 ENSPKIP00000021171 LOC111843556 LOC111843556 LOC111849531 LOC111849531 LOC111847244 LOC111847244 LOC111858344 LOC111858344 hsd11b1l hsd11b1l LOC111845480 LOC111845480 ENSPKIP00000030115 ENSPKIP00000030115 ENSPKIP00000030714 ENSPKIP00000030714 LOC111839059 LOC111839059 DHRS11 DHRS11 LOC111841056 LOC111841056 LOC111846669 LOC111846669 dhrs11 dhrs11 hsd17b3 hsd17b3 LOC111859263 LOC111859263 LOC111861141 LOC111861141 CYP19A1 CYP19A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
hsd17b7Hydroxysteroid (17-beta) dehydrogenase 7. (345 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
LOC111847995Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family. (517 aa)
hsd17b8Hydroxysteroid (17-beta) dehydrogenase 8. (280 aa)
ENSPKIP00000002284UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
ENSPKIP00000002931Steroid sulfatase (microsomal), isozyme S. (600 aa)
ENSPKIP00000003742Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (428 aa)
Hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (349 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (326 aa)
LOC111848628Sulfotransferase; Belongs to the sulfotransferase 1 family. (288 aa)
ENSPKIP00000006910Transmembrane O-methyltransferase. (259 aa)
comtCatechol-O-methyltransferase a. (264 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
LOC1118357053-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
LOC111839405Zgc:172315; Belongs to the UDP-glycosyltransferase family. (568 aa)
LOC111842469Sulfotransferase; Belongs to the sulfotransferase 1 family. (284 aa)
LOC111845911Dehydrogenase/reductase (SDR family) member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
LOC111836781Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (504 aa)
ENSPKIP00000014924Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (371 aa)
srd5a3Steroid 5 alpha-reductase 3. (316 aa)
LOC111848196Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa)
ENSPKIP00000021171Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (616 aa)
LOC111843556Hydroxysteroid (11-beta) dehydrogenase 2. (387 aa)
LOC111849531Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (534 aa)
LOC111847244Uncharacterized protein. (518 aa)
LOC111858344UDP glucuronosyltransferase 1 family, polypeptide B1; Belongs to the UDP-glycosyltransferase family. (603 aa)
hsd11b1lHydroxysteroid (11-beta) dehydrogenase 1-like b. (291 aa)
LOC111845480Uncharacterized protein. (499 aa)
ENSPKIP00000030115Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (546 aa)
ENSPKIP00000030714Uncharacterized protein. (386 aa)
LOC111839059Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (521 aa)
DHRS11Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
LOC111841056Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
LOC111846669Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (517 aa)
dhrs11Dehydrogenase/reductase (SDR family) member 11a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
LOC111859263Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (513 aa)
LOC111861141Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (503 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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