STRINGSTRING
LOC111852892 LOC111852892 LOC111844866 LOC111844866 LOC111850762 LOC111850762 LOC111858884 LOC111858884 MRAS MRAS LOC111839152 LOC111839152 rras rras ULK1 ULK1 KRAS KRAS LOC111844457 LOC111844457 VMP1 VMP1 prkaa1 prkaa1 PRKCD PRKCD LOC111845734 LOC111845734 LOC111848605 LOC111848605 atg101 atg101 rab39b rab39b LOC111855469 LOC111855469 LOC111841667 LOC111841667 LOC111841691 LOC111841691 akt1s1 akt1s1 TRAF6 TRAF6 LOC111836364 LOC111836364 LOC111846371 LOC111846371 Akt3 Akt3 LOC111860532 LOC111860532 rubcn rubcn becn1 becn1 PIK3CA PIK3CA supt20h supt20h PIK3CA-2 PIK3CA-2 LOC111860514 LOC111860514 LOC111835171 LOC111835171 LOC111839372 LOC111839372 raf1 raf1 LOC111852210 LOC111852210 atg7 atg7 bad bad mtmr3 mtmr3 pten pten LOC111833948 LOC111833948 ITPR1 ITPR1 LOC111840581 LOC111840581 ENSPKIP00000010691 ENSPKIP00000010691 LOC111842404 LOC111842404 Ppp2cb Ppp2cb LOC111835579 LOC111835579 prkcq prkcq pik3r1 pik3r1 hif1a hif1a ENSPKIP00000011511 ENSPKIP00000011511 ins ins map3k7 map3k7 LOC111842499 LOC111842499 RAB33B RAB33B LOC111847608 LOC111847608 HRAS HRAS pik3cd pik3cd LOC111846317 LOC111846317 LOC111854970 LOC111854970 LOC111851347 LOC111851347 dapk2 dapk2 rragc rragc ZFYVE1 ZFYVE1 nrbf2 nrbf2 atg14 atg14 AKT2 AKT2 tank tank LOC111850628 LOC111850628 atg12 atg12 LOC111846388 LOC111846388 c9orf72 c9orf72 mlst8 mlst8 LOC111833435 LOC111833435 snap29 snap29 LOC111835825 LOC111835825 tbk1 tbk1 ATG2B ATG2B tsc2 tsc2 LOC111859461 LOC111859461 EIF2AK4 EIF2AK4 Atg4b Atg4b LOC111845833 LOC111845833 LOC111847642 LOC111847642 atg3 atg3 LOC111847098 LOC111847098 ENSPKIP00000017376 ENSPKIP00000017376 ENSPKIP00000017793 ENSPKIP00000017793 LOC111860932 LOC111860932 atg4a atg4a RAB7B RAB7B LOC111845240 LOC111845240 LOC111839546 LOC111839546 LOC111858539 LOC111858539 rb1cc1 rb1cc1 LOC111849456 LOC111849456 ctsb ctsb LOC111851952 LOC111851952 LOC111858279 LOC111858279 LOC111858275 LOC111858275 LOC111845969 LOC111845969 LOC111847640 LOC111847640 ern1 ern1 dapk3 dapk3 Prkaa2 Prkaa2 atg10 atg10 Tsc1 Tsc1 mapk10 mapk10 LOC111854483 LOC111854483 LOC111835976 LOC111835976 LOC111844078 LOC111844078 ddit4 ddit4 eif2s1 eif2s1 rhebl1 rhebl1 TSC1 TSC1 LOC111838508 LOC111838508 WIPI1 WIPI1 LOC111859629 LOC111859629 sh3glb1 sh3glb1 irs1 irs1 nras nras Atg9a Atg9a lamp1 lamp1 pik3cb pik3cb Rab8a Rab8a LOC111851414 LOC111851414 atg4d atg4d lamp2 lamp2 cflar cflar Stk11 Stk11 pik3r3 pik3r3 WIPI2 WIPI2 map2k2 map2k2 IRS2 IRS2 akt2 akt2 LOC111841480 LOC111841480 ambra1 ambra1 prkaca prkaca mapk1 mapk1 LOC111837915 LOC111837915 atg5 atg5 Mtor Mtor atg13 atg13 RAB33B-2 RAB33B-2 ern2 ern2 LOC111841418 LOC111841418 LOC111852775 LOC111852775 atg4c atg4c LOC111840699 LOC111840699 IGF1R IGF1R pik3r4 pik3r4 uvrag uvrag igbp1 igbp1 LOC111861008 LOC111861008 rheb rheb SMCR8 SMCR8 LOC111840384 LOC111840384 Stx17 Stx17 LOC111838413 LOC111838413 Pik3c3 Pik3c3 sqstm1 sqstm1 LOC111857926 LOC111857926 camkk2 camkk2 LOC111841535 LOC111841535 LOC111840961 LOC111840961 map2k1 map2k1 ENSPKIP00000037978 ENSPKIP00000037978 LOC111841178 LOC111841178 LOC111848368 LOC111848368 MAPK8 MAPK8 MTMR4 MTMR4 LOC111849117 LOC111849117 LOC111851666 LOC111851666 Ppp2ca Ppp2ca LOC111851660 LOC111851660 bnip3 bnip3 LOC111839835 LOC111839835 wdr41 wdr41 LOC111848585 LOC111848585 mtmr14 mtmr14 LOC111860367 LOC111860367 LOC111854085 LOC111854085
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111852892Protein kinase domain-containing protein. (890 aa)
LOC111844866DEP domain containing MTOR-interacting protein. (397 aa)
LOC111850762Mitogen-activated protein kinase. (419 aa)
LOC111858884Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
MRASMuscle RAS oncogene homolog. (240 aa)
LOC111839152Zgc:73226. (192 aa)
rrasRAS related. (197 aa)
ULK1Unc-51 like autophagy activating kinase 1. (974 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC111844457Hypoxia inducible factor 1 subunit alpha. (753 aa)
VMP1Vacuole membrane protein 1. (454 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
LOC111845734Tyrosine-protein kinase receptor. (1405 aa)
LOC111848605Vesicle-associated membrane protein 8 (endobrevin). (152 aa)
atg101Autophagy related 101. (218 aa)
rab39bRAB39B, member RAS oncogene family b. (213 aa)
LOC111855469Mitogen-activated protein kinase. (422 aa)
LOC111841667Si:dkey-34d22.5. (219 aa)
LOC111841691Uncharacterized protein. (213 aa)
akt1s1AKT1 substrate 1 (proline-rich). (349 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (551 aa)
LOC111836364Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC111846371Ras-related GTP binding A. (315 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
LOC111860532Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (395 aa)
rubcnRubicon autophagy regulator. (937 aa)
becn1Beclin 1, autophagy related. (447 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
supt20hSPT20 homolog, SAGA complex component. (895 aa)
PIK3CA-2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC111860514Rubicon autophagy regulator. (862 aa)
LOC111835171BCL2 like 1. (237 aa)
LOC111839372Mitogen-activated protein kinase. (426 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase b. (681 aa)
LOC111852210Uncharacterized protein. (400 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (719 aa)
badBCL2 associated agonist of cell death b. (169 aa)
mtmr3Myotubularin related protein 3. (1163 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (425 aa)
LOC111833948Zgc:92606. (132 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2710 aa)
LOC111840581Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
ENSPKIP00000010691Uncharacterized protein. (222 aa)
LOC111842404Uncharacterized protein. (188 aa)
Ppp2cbSerine/threonine-protein phosphatase. (213 aa)
LOC111835579Si:ch73-234b20.5. (102 aa)
prkcqProtein kinase C. (719 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
hif1aHypoxia inducible factor 1 subunit alpha a. (753 aa)
ENSPKIP00000011511Uncharacterized protein. (426 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (597 aa)
LOC111842499Uncharacterized protein. (213 aa)
RAB33BRAB33B, member RAS oncogene family. (217 aa)
LOC111847608Uncharacterized protein. (212 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC111846317Uncharacterized protein. (1093 aa)
LOC111854970Si:ch211-11n16.2. (660 aa)
LOC111851347Uncharacterized protein. (208 aa)
dapk2Death-associated protein kinase 2a; Belongs to the protein kinase superfamily. (493 aa)
rragcRas-related GTP binding Ca. (380 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (767 aa)
nrbf2Nuclear receptor binding factor 2b. (254 aa)
atg14Autophagy related 14. (502 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
tankTRAF family member-associated NFKB activator. (343 aa)
LOC111850628Uncharacterized protein. (122 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (120 aa)
LOC111846388Protein kinase domain-containing protein. (551 aa)
c9orf72Zgc:100846. (464 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
LOC1118334353-phosphoinositide dependent protein kinase 1b. (560 aa)
snap29Synaptosome associated protein 29. (250 aa)
LOC111835825Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
tbk1TANK-binding kinase 1. (727 aa)
ATG2BAutophagy related 2B. (2073 aa)
tsc2TSC complex subunit 2. (1834 aa)
LOC111859461Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1645 aa)
Atg4bCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (426 aa)
LOC111845833BCL2 apoptosis regulator b. (219 aa)
LOC111847642Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
atg3Autophagy-related protein 3. (315 aa)
LOC111847098Si:dkey-26g8.5; Belongs to the peptidase C1 family. (343 aa)
ENSPKIP00000017376Uncharacterized protein. (1373 aa)
ENSPKIP00000017793Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (438 aa)
LOC111860932Uncharacterized protein. (1201 aa)
atg4aCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (410 aa)
RAB7BRAB7B, member RAS oncogene family. (198 aa)
LOC111845240Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (410 aa)
LOC111839546Serine/threonine-protein phosphatase. (309 aa)
LOC111858539RAB1A, member RAS oncogene family b. (205 aa)
rb1cc1RB1-inducible coiled-coil 1. (1611 aa)
LOC111849456Muscle RAS oncogene homolog. (133 aa)
ctsbCathepsin Ba; Belongs to the peptidase C1 family. (331 aa)
LOC111851952GABA type A receptor associated protein like 2. (117 aa)
LOC111858279Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (330 aa)
LOC111858275Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (328 aa)
LOC111845969Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (844 aa)
LOC111847640Uncharacterized protein. (668 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (993 aa)
dapk3Protein kinase domain-containing protein. (456 aa)
Prkaa2Non-specific serine/threonine protein kinase. (609 aa)
atg10ATG10 autophagy related 10 homolog (S. cerevisiae). (247 aa)
Tsc1TSC complex subunit 1a. (1125 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
LOC111854483Si:ch73-335l21.1. (1258 aa)
LOC111835976Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (402 aa)
LOC111844078Hypoxia inducible factor 1 subunit alpha, like. (632 aa)
ddit4DNA-damage-inducible transcript 4. (230 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha a. (315 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
TSC1TSC complex subunit 1. (1008 aa)
LOC111838508RAB7b, member RAS oncogene family. (205 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (492 aa)
LOC111859629Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
sh3glb1SH3-domain GRB2-like endophilin B1b. (371 aa)
irs1Insulin receptor substrate 1. (1034 aa)
nrasNRAS proto-oncogene, GTPase. (200 aa)
Atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (841 aa)
lamp1Lysosomal associated membrane protein 1b. (425 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1007 aa)
Rab8aUncharacterized protein. (303 aa)
LOC111851414Insulin receptor substrate 2. (997 aa)
atg4dCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (499 aa)
lamp2Lysosomal-associated membrane protein 2. (406 aa)
cflarCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (524 aa)
Stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (445 aa)
pik3r3Uncharacterized protein. (725 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (424 aa)
map2k2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
IRS2Insulin receptor substrate 2. (1057 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC111841480ATG16 autophagy related 16-like 2 (S. cerevisiae). (581 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1394 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC111837915Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (359 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MtorSerine/threonine-protein kinase TOR. (2399 aa)
atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (540 aa)
RAB33B-2RAB33B, member RAS oncogene family. (227 aa)
ern2Endoplasmic reticulum to nucleus signaling 2. (963 aa)
LOC111841418TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (551 aa)
LOC111852775Zgc:101559. (237 aa)
atg4cCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (482 aa)
LOC111840699HRas proto-oncogene, GTPase b. (189 aa)
IGF1RTyrosine-protein kinase receptor. (1394 aa)
pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1324 aa)
uvragUV radiation resistance associated gene. (710 aa)
igbp1Immunoglobulin (CD79A) binding protein 1. (362 aa)
LOC111861008Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (498 aa)
rhebRas homolog, mTORC1 binding. (184 aa)
SMCR8SMCR8-C9orf72 complex subunit. (932 aa)
LOC111840384Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (396 aa)
Stx17Uncharacterized protein. (86 aa)
LOC111838413Si:dkey-240h12.4; Belongs to the protein kinase superfamily. (361 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (867 aa)
sqstm1Sequestosome 1. (421 aa)
LOC111857926Uncharacterized protein. (209 aa)
camkk2Si:ch73-62l21.1. (533 aa)
LOC111841535Uncharacterized protein. (1137 aa)
LOC111840961Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
ENSPKIP00000037978High mobility group box 1a. (242 aa)
LOC111841178RAS related 2. (225 aa)
LOC111848368Mitogen-activated protein kinase. (434 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MTMR4Myotubularin related protein 4. (1184 aa)
LOC111849117Smith-Magenis syndrome chromosome region, candidate 8a. (909 aa)
LOC111851666Cathepsin 12; Belongs to the peptidase C1 family. (344 aa)
Ppp2caSerine/threonine-protein phosphatase. (366 aa)
LOC111851660BCL2 apoptosis regulator a. (230 aa)
bnip3BCL2 interacting protein 3. (191 aa)
LOC111839835Si:dkeyp-97e7.9. (401 aa)
wdr41WD repeat domain 41. (451 aa)
LOC111848585Death-associated protein kinase 1. (1433 aa)
mtmr14Myotubularin related protein 14. (648 aa)
LOC111860367Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)
LOC111854085WD repeat domain, phosphoinositide interacting 2. (425 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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