STRINGSTRING
LOC111850762 LOC111850762 Gck Gck LOC111833226 LOC111833226 KRAS KRAS LOC111855420 LOC111855420 phka1 phka1 prkaa1 prkaa1 Shc4 Shc4 LOC111857327 LOC111857327 prkci prkci GYS1 GYS1 LOC111850786 LOC111850786 LOC111855469 LOC111855469 g6pc3 g6pc3 LOC111833879 LOC111833879 Tmem145 Tmem145 LOC111840455 LOC111840455 LOC111836331 LOC111836331 CALM2 CALM2 LOC111836364 LOC111836364 ppp1r3b ppp1r3b rhoq rhoq phka2 phka2 Akt3 Akt3 LOC111851785 LOC111851785 SOS1 SOS1 LOC111860532 LOC111860532 LOC111856747 LOC111856747 PIK3CA PIK3CA inppl1 inppl1 LOC111856137 LOC111856137 PIK3CA-2 PIK3CA-2 grb2 grb2 LOC111839331 LOC111839331 ENSPKIP00000008179 ENSPKIP00000008179 LOC111839372 LOC111839372 LOC111860021 LOC111860021 raf1 raf1 bad bad ENSPKIP00000010295 ENSPKIP00000010295 Acacb Acacb rapgef1 rapgef1 LOC111842404 LOC111842404 pik3r1 pik3r1 INPP5A INPP5A ENSPKIP00000011511 ENSPKIP00000011511 ins ins LOC111848550 LOC111848550 LOC111849382 LOC111849382 HRAS HRAS pik3cd pik3cd LOC111846317 LOC111846317 LOC111847562 LOC111847562 ppp1r3a ppp1r3a AKT2 AKT2 FOXO1 FOXO1 ikbkb ikbkb LOC111846388 LOC111846388 LOC111845136 LOC111845136 g6pc g6pc LOC111834624 LOC111834624 LOC111833435 LOC111833435 LOC111860034 LOC111860034 LOC111835825 LOC111835825 tsc2 tsc2 LOC111851322 LOC111851322 PRKAG2 PRKAG2 LOC111847642 LOC111847642 LOC111847095 LOC111847095 LOC111853115 LOC111853115 LOC111855028 LOC111855028 ENSPKIP00000017793 ENSPKIP00000017793 LOC111854407 LOC111854407 ptpn1 ptpn1 LOC111860932 LOC111860932 araf araf CALML6 CALML6 LOC111860854 LOC111860854 pck1 pck1 phkb phkb LOC111847640 LOC111847640 LOC111836530 LOC111836530 ppp1r3d ppp1r3d SLC2A4 SLC2A4 LOC111851345 LOC111851345 GRB2 GRB2 Prkaa2 Prkaa2 ppp1r3c ppp1r3c phkg1 phkg1 Tsc1 Tsc1 ENSPKIP00000022831 ENSPKIP00000022831 LOC111855814 LOC111855814 prkar1b prkar1b mapk10 mapk10 LOC111855133 LOC111855133 LOC111854483 LOC111854483 rhebl1 rhebl1 TSC1 TSC1 Prkag1 Prkag1 gys2 gys2 Prkag3 Prkag3 LOC111857026 LOC111857026 prkar1a prkar1a HK1 HK1 GSK3B GSK3B irs1 irs1 nras nras LOC111849535 LOC111849535 pik3cb pik3cb Calml4 Calml4 LOC111853173 LOC111853173 LOC111851414 LOC111851414 Fasn Fasn pygb pygb LOC111841470 LOC111841470 pik3r3 pik3r3 INSR INSR SHC3 SHC3 LOC111854612 LOC111854612 map2k2 map2k2 LOC111846579 LOC111846579 IRS2 IRS2 LOC111844138 LOC111844138 akt2 akt2 flot1 flot1 Socs1 Socs1 prkaca prkaca mapk1 mapk1 Mtor Mtor LOC111859700 LOC111859700 socs3 socs3 LOC111840699 LOC111840699 braf braf LOC111861008 LOC111861008 rheb rheb LOC111860273 LOC111860273 LOC111855845 LOC111855845 SH2B2 SH2B2 EXOC7 EXOC7 ENSPKIP00000035472 ENSPKIP00000035472 ENSPKIP00000035488 ENSPKIP00000035488 LOC111841535 LOC111841535 trip10 trip10 LOC111840961 LOC111840961 map2k1 map2k1 Socs2 Socs2 ppp1cc ppp1cc LOC111840786 LOC111840786 PRKAR2B PRKAR2B flot2 flot2 LOC111835003 LOC111835003 LOC111848368 LOC111848368 srebf1 srebf1 MAPK8 MAPK8 LOC111835583 LOC111835583 PRKAB2 PRKAB2 shc2 shc2 SOS1-2 SOS1-2 LOC111851656 LOC111851656 LOC111853452 LOC111853452 LOC111846264 LOC111846264 PCK2 PCK2 LOC111859293 LOC111859293 LOC111860367 LOC111860367
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111850762Mitogen-activated protein kinase. (419 aa)
GckPhosphotransferase. (457 aa)
LOC111833226V-crk avian sarcoma virus CT10 oncogene homolog-like. (313 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC111855420Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
phka1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1231 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
Shc4PID domain-containing protein. (209 aa)
LOC111857327CBM21 domain-containing protein. (336 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (587 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (740 aa)
LOC111850786Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
LOC111855469Mitogen-activated protein kinase. (422 aa)
g6pc3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (339 aa)
LOC111833879V-crk avian sarcoma virus CT10 oncogene homolog. (314 aa)
Tmem145Transmembrane protein 145. (543 aa)
LOC111840455CRK proto-oncogene, adaptor protein. (308 aa)
LOC111836331Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (799 aa)
CALM2Calmodulin 2b, (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC111836364Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
ppp1r3bProtein phosphatase 1 regulatory subunit. (303 aa)
rhoqRas homolog family member Q. (205 aa)
phka2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1234 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
LOC111851785V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1207 aa)
LOC111860532Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (395 aa)
LOC111856747Uncharacterized protein. (410 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
inppl1Inositol polyphosphate phosphatase-like 1a. (1279 aa)
LOC111856137ETS transcription factor ELK1. (533 aa)
PIK3CA-2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC111839331Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (269 aa)
ENSPKIP00000008179Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (315 aa)
LOC111839372Mitogen-activated protein kinase. (426 aa)
LOC111860021Uncharacterized protein. (394 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase b. (681 aa)
badBCL2 associated agonist of cell death b. (169 aa)
ENSPKIP00000010295Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (212 aa)
AcacbAcetyl-CoA carboxylase beta. (2072 aa)
rapgef1Rap guanine nucleotide exchange factor (GEF) 1a. (1208 aa)
LOC111842404Uncharacterized protein. (188 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (412 aa)
ENSPKIP00000011511Uncharacterized protein. (426 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC111848550Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (338 aa)
LOC111849382Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (219 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC111846317Uncharacterized protein. (1093 aa)
LOC111847562Tyrosine-protein kinase receptor. (1448 aa)
ppp1r3aCBM21 domain-containing protein. (1366 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
FOXO1Forkhead box O1. (640 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (742 aa)
LOC111846388Protein kinase domain-containing protein. (551 aa)
LOC111845136Glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1. (420 aa)
g6pcGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
LOC111834624Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (482 aa)
LOC1118334353-phosphoinositide dependent protein kinase 1b. (560 aa)
LOC111860034Eukaryotic translation initiation factor 4E binding protein 1. (122 aa)
LOC111835825Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
tsc2TSC complex subunit 2. (1834 aa)
LOC111851322Forkhead box O1 a. (631 aa)
PRKAG2Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (522 aa)
LOC111847642Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
LOC111847095Fructose-1,6-bisphosphatase 1b; Belongs to the FBPase class 1 family. (337 aa)
LOC11185311540S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
LOC111855028Uncharacterized protein. (239 aa)
ENSPKIP00000017793Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (438 aa)
LOC111854407Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1133 aa)
ptpn1Tyrosine-protein phosphatase non-receptor type. (449 aa)
LOC111860932Uncharacterized protein. (1201 aa)
arafA-Raf proto-oncogene, serine/threonine kinase. (615 aa)
CALML6Calmodulin like 6. (170 aa)
LOC111860854Eukaryotic translation initiation factor 4E family member 2 related sequence 1; Belongs to the eukaryotic initiation factor 4E family. (230 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
phkbPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1089 aa)
LOC111847640Uncharacterized protein. (668 aa)
LOC111836530Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (726 aa)
ppp1r3dProtein phosphatase 1, regulatory subunit 3Db. (349 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (504 aa)
LOC111851345Cbl proto-oncogene, E3 ubiquitin protein ligase. (905 aa)
GRB2Growth factor receptor bound protein 2. (220 aa)
Prkaa2Non-specific serine/threonine protein kinase. (609 aa)
ppp1r3cProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (320 aa)
phkg1Phosphorylase kinase, gamma 1b (muscle); Belongs to the protein kinase superfamily. (392 aa)
Tsc1TSC complex subunit 1a. (1125 aa)
ENSPKIP00000022831CBM21 domain-containing protein. (268 aa)
LOC111855814Tyrosine-protein phosphatase non-receptor type. (419 aa)
prkar1bProtein kinase, cAMP-dependent, regulatory, type I, beta. (380 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
LOC111855133Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
LOC111854483Si:ch73-335l21.1. (1258 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
TSC1TSC complex subunit 1. (1008 aa)
Prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (325 aa)
gys2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (697 aa)
Prkag3Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (441 aa)
LOC111857026CBM21 domain-containing protein. (1141 aa)
prkar1aProtein kinase cAMP-dependent type I regulatory subunit alpha. (379 aa)
HK1Hexokinase 1. (918 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (463 aa)
irs1Insulin receptor substrate 1. (1034 aa)
nrasNRAS proto-oncogene, GTPase. (200 aa)
LOC111849535Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (276 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1007 aa)
Calml4Calmodulin-like 4a. (262 aa)
LOC111853173Suppressor of cytokine signaling 3. (208 aa)
LOC111851414Insulin receptor substrate 2. (997 aa)
FasnCoiled-coil domain containing 57. (2512 aa)
pygbAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
LOC111841470Uncharacterized protein. (631 aa)
pik3r3Uncharacterized protein. (725 aa)
INSRTyrosine-protein kinase receptor. (1398 aa)
SHC3SHC adaptor protein 3. (681 aa)
LOC111854612CBM21 domain-containing protein. (1301 aa)
map2k2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
LOC111846579Uncharacterized protein. (176 aa)
IRS2Insulin receptor substrate 2. (1057 aa)
LOC111844138Hexokinase 2. (920 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (436 aa)
Socs1Uncharacterized protein. (209 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
MtorSerine/threonine-protein kinase TOR. (2399 aa)
LOC111859700Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
socs3Suppressor of cytokine signaling 3a. (203 aa)
LOC111840699HRas proto-oncogene, GTPase b. (189 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (827 aa)
LOC111861008Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (498 aa)
rhebRas homolog, mTORC1 binding. (184 aa)
LOC111860273MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (472 aa)
LOC111855845Uncharacterized protein. (399 aa)
SH2B2SH2B adaptor protein 2. (690 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (253 aa)
ENSPKIP00000035472Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (509 aa)
ENSPKIP00000035488Hexokinase domain containing 1. (918 aa)
LOC111841535Uncharacterized protein. (1137 aa)
trip10Thyroid hormone receptor interactor 10b. (577 aa)
LOC111840961Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
Socs2Suppressor of cytokine signaling 2. (273 aa)
ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
LOC111840786Phosphodiesterase. (1066 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (401 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (439 aa)
LOC111835003Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (232 aa)
LOC111848368Mitogen-activated protein kinase. (434 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1161 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC111835583Protein kinase cAMP-dependent type II regulatory subunit beta. (451 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (306 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (675 aa)
SOS1-2SOS Ras/Rac guanine nucleotide exchange factor 1. (1316 aa)
LOC111851656Protein kinase, AMP-activated, gamma 2 non-catalytic subunit a. (569 aa)
LOC111853452Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
LOC111846264Cbl proto-oncogene. (903 aa)
PCK2Uncharacterized protein. (634 aa)
LOC111859293Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
LOC111860367Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
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