STRINGSTRING
ENSPKIP00000000180 ENSPKIP00000000180 LOC111850762 LOC111850762 LOC111834408 LOC111834408 Itpr2 Itpr2 KRAS KRAS map3k1 map3k1 PRKCD PRKCD LOC111853011 LOC111853011 adcy5 adcy5 ENSPKIP00000002834 ENSPKIP00000002834 LOC111845716 LOC111845716 LOC111850486 LOC111850486 LOC111855469 LOC111855469 LOC111839234 LOC111839234 LOC111859388 LOC111859388 CALM2 CALM2 mmp2 mmp2 LOC111836901 LOC111836901 SOS1 SOS1 LOC111839254 LOC111839254 LOC111860532 LOC111860532 LOC111856137 LOC111856137 grb2 grb2 ADCY2 ADCY2 LOC111839372 LOC111839372 adcy6 adcy6 MAPK14 MAPK14 CACNA1D CACNA1D raf1 raf1 ITPR1 ITPR1 LOC111840581 LOC111840581 LOC111842404 LOC111842404 LOC111836823 LOC111836823 LOC111849289 LOC111849289 LOC111832687 LOC111832687 HRAS HRAS fshb fshb LOC111832795 LOC111832795 ENSPKIP00000014741 ENSPKIP00000014741 LOC111858175 LOC111858175 LOC111835825 LOC111835825 ENSPKIP00000016455 ENSPKIP00000016455 LOC111837634 LOC111837634 PLCB4 PLCB4 LOC111847642 LOC111847642 MAP2K4 MAP2K4 PLCB1 PLCB1 LOC111835923 LOC111835923 GNAS GNAS LOC111845834 LOC111845834 CALML6 CALML6 ATF4 ATF4 ENSPKIP00000019632 ENSPKIP00000019632 LOC111848207 LOC111848207 PRKCA PRKCA GRB2 GRB2 ADCY9 ADCY9 PLA2G4A-2 PLA2G4A-2 LOC111841315 LOC111841315 LOC111845900 LOC111845900 LOC111855741 LOC111855741 mapk10 mapk10 GNAS-2 GNAS-2 LOC111837704 LOC111837704 LOC111835975 LOC111835975 map2k7 map2k7 adcy8 adcy8 LOC111843225 LOC111843225 LOC111835993 LOC111835993 LOC111850159 LOC111850159 ENSPKIP00000025849 ENSPKIP00000025849 LOC111836597 LOC111836597 LOC111835374 LOC111835374 MAP2K3 MAP2K3 LOC111853904 LOC111853904 LOC111851449 LOC111851449 LOC111854546 LOC111854546 nras nras LOC111855160 LOC111855160 ENSPKIP00000027496 ENSPKIP00000027496 Calml4 Calml4 map2k2 map2k2 LOC111846579 LOC111846579 LOC111856451 LOC111856451 LOC111837851 LOC111837851 ENSPKIP00000032599 ENSPKIP00000032599 PRKCB PRKCB prkaca prkaca mapk1 mapk1 LOC111840699 LOC111840699 LOC111859759 LOC111859759 Map2k6 Map2k6 ENSPKIP00000035895 ENSPKIP00000035895 LOC111857950 LOC111857950 LOC111840961 LOC111840961 map2k1 map2k1 LOC111857883 LOC111857883 LOC111840348 LOC111840348 Cga Cga LOC111848368 LOC111848368 gnrh2 gnrh2 map3k4 map3k4 MAPK8 MAPK8 ENSPKIP00000039408 ENSPKIP00000039408 LOC111860249 LOC111860249 LOC111852859 LOC111852859 LOC111853435 LOC111853435 SOS1-2 SOS1-2 LOC111850848 LOC111850848 LOC111845666 LOC111845666 ENSPKIP00000041666 ENSPKIP00000041666 LOC111841598 LOC111841598 ENSPKIP00000041773 ENSPKIP00000041773 LOC111860367 LOC111860367
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPKIP00000000180BZIP domain-containing protein. (393 aa)
LOC111850762Mitogen-activated protein kinase. (419 aa)
LOC111834408Cell division cycle 42. (191 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2646 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
map3k1Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1478 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
LOC111853011Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (478 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
ENSPKIP00000002834Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
LOC111845716G_PROTEIN_RECEP_F1_2 domain-containing protein. (411 aa)
LOC111850486Phospholipase. (1035 aa)
LOC111855469Mitogen-activated protein kinase. (422 aa)
LOC111839234Uncharacterized protein. (359 aa)
LOC111859388Gonadotropin releasing hormone receptor 4. (422 aa)
CALM2Calmodulin 2b, (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
mmp2Matrix metallopeptidase 2. (658 aa)
LOC111836901Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1207 aa)
LOC111839254Amphiregulin. (238 aa)
LOC111860532Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (395 aa)
LOC111856137ETS transcription factor ELK1. (533 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
LOC111839372Mitogen-activated protein kinase. (426 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
MAPK14Mitogen-activated protein kinase. (362 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2029 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase b. (681 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2710 aa)
LOC111840581Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
LOC111842404Uncharacterized protein. (188 aa)
LOC111836823Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1099 aa)
LOC111849289Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
LOC111832687Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
fshbFollicle stimulating hormone subunit beta. (124 aa)
LOC111832795G_PROTEIN_RECEP_F1_2 domain-containing protein. (378 aa)
ENSPKIP00000014741Luteinizing hormone, beta polypeptide. (126 aa)
LOC111858175Matrix metallopeptidase 2. (657 aa)
LOC111835825Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
ENSPKIP00000016455Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (481 aa)
LOC111837634Uncharacterized protein. (617 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1218 aa)
LOC111847642Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
MAP2K4Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (449 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1221 aa)
LOC111835923Tyrosine-protein kinase. (529 aa)
GNASGNAS complex locus. (418 aa)
LOC111845834Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
CALML6Calmodulin like 6. (170 aa)
ATF4Activating transcription factor 4a. (403 aa)
ENSPKIP00000019632Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2013 aa)
LOC111848207Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
GRB2Growth factor receptor bound protein 2. (220 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1434 aa)
PLA2G4A-2Phospholipase A2. (718 aa)
LOC111841315Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (999 aa)
LOC111845900Receptor protein-tyrosine kinase. (1210 aa)
LOC111855741Tyrosine-protein kinase. (551 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
GNAS-2GNAS complex locus. (378 aa)
LOC111837704Matrix metallopeptidase 14a (membrane-inserted). (569 aa)
LOC111835975BZIP domain-containing protein. (406 aa)
map2k7Mitogen-activated protein kinase kinase 7. (438 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1222 aa)
LOC111843225Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
LOC111835993Mitogen-activated protein kinase. (388 aa)
LOC111850159Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
ENSPKIP00000025849Uncharacterized protein. (269 aa)
LOC111836597Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
LOC111835374Cell division cycle 42, like. (191 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
LOC111853904Mitogen-activated protein kinase. (363 aa)
LOC111851449Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (592 aa)
LOC111854546Matrix metallopeptidase 14b (membrane-inserted). (615 aa)
nrasNRAS proto-oncogene, GTPase. (200 aa)
LOC111855160Heparin-binding EGF-like growth factor a. (220 aa)
ENSPKIP00000027496Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (319 aa)
Calml4Calmodulin-like 4a. (262 aa)
map2k2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
LOC111846579Uncharacterized protein. (176 aa)
LOC111856451Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1206 aa)
LOC111837851Protein kinase domain-containing protein. (608 aa)
ENSPKIP00000032599G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC111840699HRas proto-oncogene, GTPase b. (189 aa)
LOC111859759Protein kinase domain-containing protein. (398 aa)
Map2k6Mitogen-activated protein kinase kinase 6. (398 aa)
ENSPKIP00000035895Uncharacterized protein. (209 aa)
LOC111857950Protein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (998 aa)
LOC111840961Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC1118578831-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1218 aa)
LOC111840348Mitogen-activated protein kinase. (359 aa)
CgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
LOC111848368Mitogen-activated protein kinase. (434 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (87 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1613 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSPKIP00000039408Phospholipase A2. (736 aa)
LOC111860249Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC111852859Mitogen-activated protein kinase kinase kinase 3. (618 aa)
LOC111853435Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1. (633 aa)
SOS1-2SOS Ras/Rac guanine nucleotide exchange factor 1. (1316 aa)
LOC111850848Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (479 aa)
LOC111845666Mitogen-activated protein kinase. (361 aa)
ENSPKIP00000041666Phospholipase. (1019 aa)
LOC111841598Receptor protein-tyrosine kinase. (1203 aa)
ENSPKIP00000041773Heparin-binding EGF-like growth factor b. (135 aa)
LOC111860367Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)
Your Current Organism:
Paramormyrops kingsleyae
NCBI taxonomy Id: 1676925
Other names: Brienomyrus kingsleyae, Brienomyrus sp. CAB, Mormyrus kingsleyae, P. kingsleyae, Pollimyrus kingsleyae
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.