STRINGSTRING
dapB dapB recQ recQ purK purK rbsK-2 rbsK-2 purD purD purM purM AMK58409.1 AMK58409.1 AMK58408.1 AMK58408.1 AMK58589.1 AMK58589.1 purC purC purT purT hrpA hrpA hflX hflX nrdR nrdR AMK58395.1 AMK58395.1 AMK58393.1 AMK58393.1 AMK58391.1 AMK58391.1 AMK58387.1 AMK58387.1 AMK58377.1 AMK58377.1 AMK58376.1 AMK58376.1 AMK58375.1 AMK58375.1 AMK58373.1 AMK58373.1 AMK58584.1 AMK58584.1 glnA-2 glnA-2 lpdA lpdA pheS pheS pheT pheT argC argC argB argB argG argG AMK58353.1 AMK58353.1 tyrS tyrS nadK nadK recN recN proA proA nadD nadD mfd mfd AMK58573.1 AMK58573.1 AMK58568.1 AMK58568.1 AMK58297.1 AMK58297.1 AMK58564.1 AMK58564.1 coaE coaE uvrB uvrB pyk pyk AMK58561.1 AMK58561.1 AMK58276.1 AMK58276.1 AMK58271.1 AMK58271.1 guaA guaA ackA ackA prs-2 prs-2 clpX clpX AMK58247.1 AMK58247.1 AMK58244.1 AMK58244.1 AMK58237.1 AMK58237.1 ychF ychF AMK58227.1 AMK58227.1 AMK58226.1 AMK58226.1 AMK58209.1 AMK58209.1 AMK58208.1 AMK58208.1 gnd gnd AMK58205.1 AMK58205.1 zwf zwf AMK58186.1 AMK58186.1 AMK58181.1 AMK58181.1 AMK58180.1 AMK58180.1 AMK58179.1 AMK58179.1 AMK58176.1 AMK58176.1 alaS alaS aroB aroB pyrG pyrG sufC sufC AMK58158.1 AMK58158.1 glgC glgC AMK58153.1 AMK58153.1 AMK58151.1 AMK58151.1 era era AMK58148.1 AMK58148.1 pyrH pyrH hisE hisE hisG hisG AMK58119.1 AMK58119.1 der der sucD sucD sucC sucC ruvB ruvB ruvA ruvA thrS thrS AMK58095.1 AMK58095.1 leuS leuS AMK58086.1 AMK58086.1 AMK58084.1 AMK58084.1 lepA lepA AMK58062.1 AMK58062.1 AMK58061.1 AMK58061.1 dnaJ dnaJ pgk pgk AMK58045.1 AMK58045.1 uvrA uvrA AMK58040.1 AMK58040.1 nnrE nnrE AMK58026.1 AMK58026.1 glnE glnE AMK58007.1 AMK58007.1 AMK58003.1 AMK58003.1 AMK57994.1 AMK57994.1 AMK57983.1 AMK57983.1 nadE nadE AMK57975.1 AMK57975.1 AMK57968.1 AMK57968.1 AMK57961.1 AMK57961.1 rbsK rbsK AMK57956.1 AMK57956.1 AMK57953.1 AMK57953.1 AMK57951.1 AMK57951.1 AMK57947.1 AMK57947.1 secA secA recA recA AMK58539.1 AMK58539.1 AMK57932.1 AMK57932.1 miaA miaA AMK57923.1 AMK57923.1 AMK57915.1 AMK57915.1 AMK57914.1 AMK57914.1 AMK57910.1 AMK57910.1 typA typA AMK58534.1 AMK58534.1 AMK57898.1 AMK57898.1 asnB asnB AMK57892.1 AMK57892.1 gap gap murE-2 murE-2 murE murE AMK57885.1 AMK57885.1 folC folC AMK57880.1 AMK57880.1 AMK57879.1 AMK57879.1 ftsZ ftsZ AMK58530.1 AMK58530.1 glyQS glyQS AMK57857.1 AMK57857.1 AMK57856.1 AMK57856.1 thiM thiM gmk gmk carB carB carA carA AMK57843.1 AMK57843.1 murC murC murD murD murF murF AMK57834.1 AMK57834.1 AMK57830.1 AMK57830.1 AMK57829.1 AMK57829.1 hisD hisD tuf tuf fusA fusA pafA pafA arc arc AMK57786.1 AMK57786.1 metK metK AMK57769.1 AMK57769.1 AMK57768.1 AMK57768.1 AMK57767.1 AMK57767.1 AMK57761.1 AMK57761.1 aspS aspS hisS hisS AMK57751.1 AMK57751.1 ftsE ftsE dxr dxr AMK57723.1 AMK57723.1 AMK58515.1 AMK58515.1 AMK57701.1 AMK57701.1 metN metN AMK57695.1 AMK57695.1 proS proS guaB guaB AMK57678.1 AMK57678.1 AMK57677.1 AMK57677.1 xylB xylB AMK57650.1 AMK57650.1 folK folK folE folE hflB hflB hpt hpt gltX gltX fhs fhs tmk tmk murB murB groS groS AMK57598.1 AMK57598.1 pstB pstB AMK57576.1 AMK57576.1 AMK57572.1 AMK57572.1 AMK58501.1 AMK58501.1 rdgB rdgB coaD coaD ilvB ilvB Bang102_003005 Bang102_003005 cysS cysS ffh ffh AMK58492.1 AMK58492.1 ddl ddl gpsA gpsA AMK57516.1 AMK57516.1 AMK57505.1 AMK57505.1 proB proB obgE obgE AMK57488.1 AMK57488.1 thrB thrB AMK57485.1 AMK57485.1 argS argS AMK57476.1 AMK57476.1 atpD atpD atpG atpG atpA atpA valS valS rho rho gatB gatB gatA gatA gatC gatC AMK57440.1 AMK57440.1 AMK57438.1 AMK57438.1 ilvC-2 ilvC-2 ilvC ilvC galK galK AMK57414.1 AMK57414.1 grpE grpE dnaK dnaK AMK57394.1 AMK57394.1 dcd dcd AMK57382.1 AMK57382.1 AMK57380.1 AMK57380.1 AMK57379.1 AMK57379.1 gyrA gyrA gyrB gyrB recF recF dnaA dnaA AMK57363.1 AMK57363.1 ispE ispE AMK57353.1 AMK57353.1 AMK57352.1 AMK57352.1 metG metG AMK57346.1 AMK57346.1 AMK57344.1 AMK57344.1 AMK57342.1 AMK57342.1 Bang102_001860 Bang102_001860 trpS trpS AMK58478.1 AMK58478.1 AMK57322.1 AMK57322.1 AMK57311.1 AMK57311.1 purA purA AMK57289.1 AMK57289.1 Bang102_001475 Bang102_001475 coaX coaX coaBC coaBC AMK57276.1 AMK57276.1 groEL groEL AMK57262.1 AMK57262.1 AMK57261.1 AMK57261.1 clpB clpB AMK58464.1 AMK58464.1 upp upp AMK57242.1 AMK57242.1 AMK57241.1 AMK57241.1 AMK57226.1 AMK57226.1 AMK57225.1 AMK57225.1 ftsY ftsY dnaB dnaB AMK57212.1 AMK57212.1 AMK57209.1 AMK57209.1 ppk1 ppk1 AMK57203.1 AMK57203.1 AMK57202.1 AMK57202.1 dnaX dnaX asd asd pdxB pdxB adk adk AMK57144.1 AMK57144.1 infB infB AMK57138.1 AMK57138.1 radA radA serS serS lysS lysS AMK57115.1 AMK57115.1 AMK57109.1 AMK57109.1 folA folA AMK58450.1 AMK58450.1 AMK57068.1 AMK57068.1 AMK57066.1 AMK57066.1 AMK58446.1 AMK58446.1 AMK57065.1 AMK57065.1 AMK57064.1 AMK57064.1 nrdD nrdD AMK57052.1 AMK57052.1 AMK57043.1 AMK57043.1 AMK58441.1 AMK58441.1 ileS ileS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (251 aa)
recQATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (647 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (395 aa)
rbsK-2Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (326 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (422 aa)
purMPhosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AMK58409.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (174 aa)
AMK58408.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (819 aa)
AMK58589.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (250 aa)
purTPhosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (431 aa)
hrpAATP-dependent RNA helicase HrpA; Derived by automated computational analysis using gene prediction method: Protein Homology. (1346 aa)
hflXGTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. (498 aa)
nrdRNrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (153 aa)
AMK58395.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (856 aa)
AMK58393.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AMK58391.1Cobalt ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (795 aa)
AMK58387.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AMK58377.1Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AMK58376.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AMK58375.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (761 aa)
AMK58373.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (381 aa)
AMK58584.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
glnA-2Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
lpdADihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
pheSphenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (355 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (869 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (364 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (317 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (412 aa)
AMK58353.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (440 aa)
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (324 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (590 aa)
proAGamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (429 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (236 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1176 aa)
AMK58573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
AMK58568.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
AMK58297.1Protein-tyrosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AMK58564.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (703 aa)
pykPyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AMK58561.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (720 aa)
AMK58276.1Lantibiotic ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
AMK58271.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (465 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa)
prs-2Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa)
clpXtRNA-Arg; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (444 aa)
AMK58247.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AMK58244.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
AMK58237.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
ychFGTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (364 aa)
AMK58227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (187 aa)
AMK58226.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (737 aa)
AMK58209.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AMK58208.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
gndPhosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
AMK58205.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (97 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (522 aa)
AMK58186.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AMK58181.1ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (870 aa)
AMK58180.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)
AMK58179.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AMK58176.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (550 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (553 aa)
sufCFe-S cluster assembly ATPase SufC; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AMK58158.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (415 aa)
AMK58153.1Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
AMK58151.1Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (325 aa)
AMK58148.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
AMK58119.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (858 aa)
derCytidylate kinase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. (709 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (306 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (353 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (677 aa)
AMK58095.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (978 aa)
AMK58086.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMK58084.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1229 aa)
lepAElongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (626 aa)
AMK58062.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (475 aa)
AMK58061.1NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (380 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (401 aa)
AMK58045.1RNase adaptor protein RapZ; Displays ATPase and GTPase activities. (318 aa)
uvrAABC-ATPase UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (997 aa)
AMK58040.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
nnrECarbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. (596 aa)
AMK58026.12-polyprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
glnEGlutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] (1034 aa)
AMK58007.1Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AMK58003.1Derived by automated computational analysis using gene prediction method: Protein Homology. (722 aa)
AMK57994.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (485 aa)
AMK57983.1Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (565 aa)
AMK57975.1ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (267 aa)
AMK57968.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (774 aa)
AMK57961.1DNA topoisomerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (897 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (333 aa)
AMK57956.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1549 aa)
AMK57953.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1055 aa)
AMK57951.1DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (764 aa)
AMK57947.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (707 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (949 aa)
recADNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (395 aa)
AMK58539.1Ectoine/hydroxyectoine ABC transporter ATP-binding protein EhuA; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AMK57932.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (942 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (333 aa)
AMK57923.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
AMK57915.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (668 aa)
AMK57914.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AMK57910.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
typAGTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (643 aa)
AMK58534.1L-aspartate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
AMK57898.1Chromosome partitioning ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
asnBAsparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)
AMK57892.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (352 aa)
murE-2UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. MurE subfamily. (518 aa)
AMK57885.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
folCDihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AMK57880.1Glutathione ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (578 aa)
AMK57879.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (412 aa)
AMK58530.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (380 aa)
glyQSglycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (491 aa)
AMK57857.1Type II secretion system protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
AMK57856.1Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (302 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1127 aa)
carACarbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (393 aa)
AMK57843.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (482 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (518 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (484 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (488 aa)
AMK57834.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AMK57830.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
AMK57829.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (465 aa)
tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (708 aa)
pafAPup--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
arcProteasome ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
AMK57786.1Primosome assembly protein PriA; Derived by automated computational analysis using gene prediction method: Protein Homology. (791 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (405 aa)
AMK57769.1Dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AMK57768.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AMK57767.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AMK57761.1Glutamate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
aspSaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (599 aa)
hisShistidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AMK57751.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (307 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (383 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
AMK57723.1Lon protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AMK58515.1DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
AMK57701.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (239 aa)
metNMethionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (362 aa)
AMK57695.1Glutamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (607 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (517 aa)
AMK57678.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AMK57677.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
xylBAcetyltransferase; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
AMK57650.1Energy-dependent translational throttle protein EttA; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (521 aa)
folEGTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
hflBAAA family ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (692 aa)
hptHypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (187 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (506 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (505 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (394 aa)
groSCo-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (97 aa)
AMK57598.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (197 aa)
pstBPhosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (259 aa)
AMK57576.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1202 aa)
AMK57572.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (500 aa)
AMK58501.1Protein-tyrosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
rdgBNon-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (219 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
ilvBAcetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
Bang102_003005Adenosine deaminase; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (720 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (548 aa)
ffhSignal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (549 aa)
AMK58492.1ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. (817 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (377 aa)
gpsAGlycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (332 aa)
AMK57516.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AMK57505.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa)
obgEGTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (558 aa)
AMK57488.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (329 aa)
AMK57485.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AMK57476.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
atpDATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (491 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (302 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (542 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (917 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (654 aa)
gatBglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (498 aa)
gatAaspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (512 aa)
gatCasparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (99 aa)
AMK57440.1Heavy metal transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (920 aa)
AMK57438.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
ilvC-2Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (349 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (350 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (391 aa)
AMK57414.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (347 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (211 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (623 aa)
AMK57394.1NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (193 aa)
AMK57382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (509 aa)
AMK57380.1Lipopolysaccharide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AMK57379.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (375 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (896 aa)
gyrBDNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (717 aa)
recFDNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (384 aa)
dnaAChromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (516 aa)
AMK57363.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (548 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa)
AMK57353.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (669 aa)
AMK57352.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (620 aa)
AMK57346.1Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AMK57344.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AMK57342.1Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
Bang102_001860tRNA-Ala; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
trpStryptophan--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (366 aa)
AMK58478.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
AMK57322.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AMK57311.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
AMK57289.1Sugar ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
Bang102_001475Glycosyl transferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa)
coaBCPhosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AMK57276.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
groELMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (541 aa)
AMK57262.1Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
AMK57261.1ATP-dependent Clp protease ATP-binding subunit ClpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (881 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (904 aa)
AMK58464.1glutamyl-Q tRNA(Asp) synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (381 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa)
AMK57242.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
AMK57241.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
AMK57226.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AMK57225.1FMN-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (420 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (456 aa)
AMK57212.1Glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AMK57209.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
ppk1RNA degradosome polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (745 aa)
AMK57203.1Pilus assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AMK57202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (220 aa)
dnaXDNA polymerase III subunit gamma/tau; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (907 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (364 aa)
pdxBHydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (188 aa)
AMK57144.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (118 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (919 aa)
AMK57138.1Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (474 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (428 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (557 aa)
AMK57115.1Oleate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
AMK57109.1Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
folADiacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dihydrofolate reductase family. (220 aa)
AMK58450.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AMK57068.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AMK57066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (376 aa)
AMK58446.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1361 aa)
AMK57065.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1288 aa)
AMK57064.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
nrdDAnaerobic ribonucleoside triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
AMK57052.1Gamma-glutamylcysteine synthetase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (425 aa)
AMK57043.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)
AMK58441.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa)
ileSHypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1101 aa)
Your Current Organism:
Bifidobacterium angulatum
NCBI taxonomy Id: 1683
Other names: AS 1.2265, ATCC 27535, B. angulatum, BCRC 14665, CCRC 14665, CCRC:14665, CCUG 24039, CCUG 24605, CIP 104167, DSM 20098, JCM 7096, LMG 10503, LMG 11039, LMG:10503, LMG:11039, NCFB 2236, NCIMB 702236
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