STRINGSTRING
A0A316TWR5 A0A316TWR5 A0A316TWV7 A0A316TWV7 A0A316TX11 A0A316TX11 A0A316TXK4 A0A316TXK4 A0A316TXM2 A0A316TXM2 A0A316TXS7 A0A316TXS7 A0A316TXU7 A0A316TXU7 A0A316TY07 A0A316TY07 A0A316TZE3 A0A316TZE3 A0A316TZF2 A0A316TZF2 A0A316TZQ7 A0A316TZQ7 A0A316TZR2 A0A316TZR2 A0A316TZS2 A0A316TZS2 A0A316TZU3 A0A316TZU3 A0A316TZW3 A0A316TZW3 A0A316U017 A0A316U017 A0A316U037 A0A316U037 A0A316U0T1 A0A316U0T1 UNG1 UNG1 A0A316U1C8 A0A316U1C8 MCM7 MCM7 A0A316U221 A0A316U221 A0A316U2A0 A0A316U2A0 A0A316U2E1 A0A316U2E1 A0A316U2H8 A0A316U2H8 A0A316U2Q6 A0A316U2Q6 A0A316U2R0 A0A316U2R0 A0A316U2S3 A0A316U2S3 A0A316U2T1 A0A316U2T1 A0A316U2V2 A0A316U2V2 A0A316U2Z7 A0A316U2Z7 A0A316U312 A0A316U312 A0A316U328 A0A316U328 A0A316U3E9 A0A316U3E9 A0A316U3J0 A0A316U3J0 A0A316U3J1 A0A316U3J1 A0A316U3N5 A0A316U3N5 A0A316U3T0 A0A316U3T0 A0A316U3U0 A0A316U3U0 A0A316U3U1 A0A316U3U1 A0A316U3Z4 A0A316U3Z4 A0A316U413 A0A316U413 A0A316U427 A0A316U427 A0A316U431 A0A316U431 A0A316U444 A0A316U444 A0A316U481 A0A316U481 FEN1 FEN1 A0A316U4F1 A0A316U4F1 A0A316U4S1 A0A316U4S1 A0A316U4S7 A0A316U4S7 A0A316U4U2 A0A316U4U2 A0A316U4V3 A0A316U4V3 A0A316U4V5 A0A316U4V5 A0A316U4Y2 A0A316U4Y2 A0A316U502 A0A316U502 A0A316U5A5 A0A316U5A5 A0A316U5G6 A0A316U5G6 A0A316U5H0 A0A316U5H0 A0A316U5M3 A0A316U5M3 A0A316U5N6 A0A316U5N6 A0A316U5T8 A0A316U5T8 A0A316U5U6 A0A316U5U6 A0A316U5V3 A0A316U5V3 A0A316U5X7 A0A316U5X7 A0A316U639 A0A316U639 A0A316U6N1 A0A316U6N1 A0A316U6N5 A0A316U6N5 A0A316U6S1 A0A316U6S1 A0A316U6S9 A0A316U6S9 A0A316U6W3 A0A316U6W3 A0A316U6W6 A0A316U6W6 A0A316U6X2 A0A316U6X2 A0A316U6Y4 A0A316U6Y4 A0A316U711 A0A316U711 A0A316U717 A0A316U717 A0A316U744 A0A316U744 A0A316U7N5 A0A316U7N5 A0A316U830 A0A316U830 A0A316U884 A0A316U884 A0A316U8F5 A0A316U8F5 A0A316U8G9 A0A316U8G9 A0A316U8M9 A0A316U8M9 A0A316U8Q0 A0A316U8Q0 A0A316U912 A0A316U912 A0A316U914 A0A316U914 A0A316U924 A0A316U924 A0A316U9B0 A0A316U9B0 A0A316U9E1 A0A316U9E1 A0A316U9I8 A0A316U9I8 A0A316U9M0 A0A316U9M0 A0A316U9P2 A0A316U9P2 A0A316U9Z8 A0A316U9Z8 A0A316UA45 A0A316UA45 A0A316UA94 A0A316UA94 A0A316UAB0 A0A316UAB0 A0A316UAB9 A0A316UAB9 A0A316UAD3 A0A316UAD3 A0A316UAE6 A0A316UAE6 A0A316UAN2 A0A316UAN2 A0A316UAP6 A0A316UAP6 A0A316UAT1 A0A316UAT1 A0A316UAT7 A0A316UAT7 A0A316UAU7 A0A316UAU7 A0A316UAW5 A0A316UAW5 A0A316UAX8 A0A316UAX8 A0A316UB22 A0A316UB22 A0A316UB24 A0A316UB24 A0A316UB32 A0A316UB32 A0A316UB35 A0A316UB35 A0A316UB45 A0A316UB45 A0A316UB61 A0A316UB61 A0A316UB97 A0A316UB97 A0A316UBG8 A0A316UBG8 A0A316UBR0 A0A316UBR0 A0A316UBT4 A0A316UBT4 A0A316UBU0 A0A316UBU0 A0A316UBU8 A0A316UBU8 A0A316UBV5 A0A316UBV5 A0A316UC36 A0A316UC36 A0A316UC71 A0A316UC71 A0A316UCG5 A0A316UCG5 A0A316UCK4 A0A316UCK4 A0A316UCQ8 A0A316UCQ8 A0A316UCT8 A0A316UCT8 A0A316UD07 A0A316UD07 A0A316UD24 A0A316UD24 A0A316UD46 A0A316UD46 A0A316UD50 A0A316UD50 A0A316UDB6 A0A316UDB6 A0A316UDG3 A0A316UDG3 A0A316UDI1 A0A316UDI1 A0A316UDQ8 A0A316UDQ8 A0A316UDR8 A0A316UDR8 A0A316UE21 A0A316UE21 A0A316UE22 A0A316UE22 A0A316UEJ8 A0A316UEJ8 A0A316UEN1 A0A316UEN1 A0A316UET1 A0A316UET1 A0A316UF20 A0A316UF20 A0A316UF35 A0A316UF35 A0A316UF90 A0A316UF90 A0A316UF92 A0A316UF92 A0A316UFA9 A0A316UFA9 A0A316UFB3 A0A316UFB3 A0A316UFD4 A0A316UFD4 A0A316UFI0 A0A316UFI0 A0A316UFL9 A0A316UFL9 A0A316UFQ9 A0A316UFQ9 A0A316UFZ5 A0A316UFZ5 A0A316UG23 A0A316UG23 A0A316UG70 A0A316UG70 A0A316UG99 A0A316UG99 A0A316UGB6 A0A316UGB6 A0A316UGD6 A0A316UGD6 A0A316UGN6 A0A316UGN6 A0A316UGY6 A0A316UGY6 A0A316UHC1 A0A316UHC1 A0A316UI28 A0A316UI28 A0A316UIT5 A0A316UIT5 A0A316UJK9 A0A316UJK9 A0A316UJP0 A0A316UJP0 A0A316UK18 A0A316UK18 A0A316ULL4 A0A316ULL4 A0A316UM03 A0A316UM03
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A316TWR5DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (588 aa)
A0A316TWV7Uncharacterized protein. (778 aa)
A0A316TX11UvrD/REP type DNA helicase. (582 aa)
A0A316TXK4Kinase-like protein; Belongs to the protein kinase superfamily. (158 aa)
A0A316TXM2UDG domain-containing protein. (462 aa)
A0A316TXS7TOPEUc domain-containing protein. (1074 aa)
A0A316TXU7HD domain-containing protein. (332 aa)
A0A316TY07Ku DNA-binding complex, Ku70 subunit. (660 aa)
A0A316TZE3Kinase-like protein. (414 aa)
A0A316TZF2Uncharacterized protein. (1046 aa)
A0A316TZQ7Uncharacterized protein. (515 aa)
A0A316TZR2Uncharacterized protein. (270 aa)
A0A316TZS2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2619 aa)
A0A316TZU3Putative RFC5-DNA replication factor C, 40 kd subunit. (353 aa)
A0A316TZW3DNA repair protein rad10. (195 aa)
A0A316U017Uncharacterized protein. (1399 aa)
A0A316U037PIN domain-like protein. (1723 aa)
A0A316U0T1Uncharacterized protein. (1223 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (489 aa)
A0A316U1C8DNA helicase; Belongs to the MCM family. (871 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (875 aa)
A0A316U221DNA helicase; Belongs to the MCM family. (971 aa)
A0A316U2A0Rhodanese domain-containing protein. (159 aa)
A0A316U2E1Putative RFC4-DNA replication factor C, 37 kDa subunit. (337 aa)
A0A316U2H8Uncharacterized protein. (1201 aa)
A0A316U2Q6ERCC4 domain-containing protein. (1111 aa)
A0A316U2R0Protein kinase domain-containing protein. (1421 aa)
A0A316U2S3Ribonuclease H-like protein. (183 aa)
A0A316U2T1Uncharacterized protein. (198 aa)
A0A316U2V2TIMELESS domain-containing protein. (1329 aa)
A0A316U2Z7Ribonuclease H-like protein. (202 aa)
A0A316U312Uncharacterized protein. (541 aa)
A0A316U328ATP-dependent DNA ligase. (1009 aa)
A0A316U3E9PIN domain-like protein. (806 aa)
A0A316U3J0DNA ligase/mRNA capping enzyme. (460 aa)
A0A316U3J1DNA glycosylase. (456 aa)
A0A316U3N5Uncharacterized protein. (638 aa)
A0A316U3T0DNA helicase; Belongs to the MCM family. (910 aa)
A0A316U3U0Uncharacterized protein. (541 aa)
A0A316U3U1Uncharacterized protein. (330 aa)
A0A316U3Z4ENDO3c domain-containing protein. (1252 aa)
A0A316U413Putative RAD54-DNA-dependent ATPase of the Snf2p family. (853 aa)
A0A316U427Putative endonuclease 4. (320 aa)
A0A316U431Rhodanese domain-containing protein. (1153 aa)
A0A316U444ORC_WH_C domain-containing protein. (574 aa)
A0A316U481Ribonuclease H-like protein. (174 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A316U4F1DNA polymerase. (1077 aa)
A0A316U4S1Pkinase-domain-containing protein. (822 aa)
A0A316U4S7PNK3P-domain-containing protein. (535 aa)
A0A316U4U2RECA_2 domain-containing protein. (745 aa)
A0A316U4V3Uncharacterized protein. (655 aa)
A0A316U4V5Cyclin-like protein. (105 aa)
A0A316U4Y2Uncharacterized protein. (479 aa)
A0A316U502Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3130 aa)
A0A316U5A5DNA-binding protein. (484 aa)
A0A316U5G6Uncharacterized protein. (559 aa)
A0A316U5H0Phospholipase C/P1 nuclease. (456 aa)
A0A316U5M3Uncharacterized protein. (629 aa)
A0A316U5N6Rad52/22 double-strand break repair protein. (143 aa)
A0A316U5T8DNA repair protein. (253 aa)
A0A316U5U6WD_REPEATS_REGION domain-containing protein. (1277 aa)
A0A316U5V3Uncharacterized protein. (206 aa)
A0A316U5X7Uncharacterized protein. (252 aa)
A0A316U639Psf2-domain-containing protein. (267 aa)
A0A316U6N1Uncharacterized protein. (1839 aa)
A0A316U6N5Uncharacterized protein. (3093 aa)
A0A316U6S1RMI1_N domain-containing protein. (470 aa)
A0A316U6S9DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (712 aa)
A0A316U6W3Uncharacterized protein. (431 aa)
A0A316U6W6DUF455-domain-containing protein. (588 aa)
A0A316U6X2DNA ligase. (905 aa)
A0A316U6Y4DNA topoisomerase IV, alpha subunit. (430 aa)
A0A316U711Uncharacterized protein. (389 aa)
A0A316U717Uncharacterized protein. (1051 aa)
A0A316U744DNA polymerase. (1644 aa)
A0A316U7N5DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (740 aa)
A0A316U830Uncharacterized protein. (607 aa)
A0A316U884Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (271 aa)
A0A316U8F5DNA/RNA polymerase. (840 aa)
A0A316U8G9Cauli_VI domain-containing protein. (198 aa)
A0A316U8M9ATPase_AAA_core domain-containing protein. (678 aa)
A0A316U8Q0Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (253 aa)
A0A316U912CDC45-like protein. (804 aa)
A0A316U914DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1170 aa)
A0A316U924Uncharacterized protein. (815 aa)
A0A316U9B0Pkinase-domain-containing protein. (686 aa)
A0A316U9E1DNA mismatch repair protein MutL. (1066 aa)
A0A316U9I8DNA_MISMATCH_REPAIR_2 domain-containing protein. (731 aa)
A0A316U9M0Nucleic acid-binding protein. (185 aa)
A0A316U9P2Zf-primase domain-containing protein. (254 aa)
A0A316U9Z8Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (505 aa)
A0A316UA45Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (326 aa)
A0A316UA94Vezatin domain-containing protein. (1370 aa)
A0A316UAB0Uncharacterized protein. (492 aa)
A0A316UAB9Putative RFC3-DNA replication factor C, 40 kDa subunit. (383 aa)
A0A316UAD3Type II DNA topoisomerase. (1837 aa)
A0A316UAE6DNA_pol_E_B domain-containing protein. (621 aa)
A0A316UAN2Cyclin-domain-containing protein. (660 aa)
A0A316UAP6RnaseH-domain-containing protein. (201 aa)
A0A316UAT1Uncharacterized protein. (398 aa)
A0A316UAT7Uncharacterized protein. (672 aa)
A0A316UAU7DNA binding methylated-DNA--cysteine S-methyltransferase. (131 aa)
A0A316UAW5Caleosin-domain-containing protein. (256 aa)
A0A316UAX8BRCT domain-containing protein. (899 aa)
A0A316UB22Uncharacterized protein. (812 aa)
A0A316UB24Uncharacterized protein. (722 aa)
A0A316UB32PRMT5-domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (1049 aa)
A0A316UB35BRCT domain-containing protein. (458 aa)
A0A316UB45DNA mismatch repair protein MutL. (767 aa)
A0A316UB61Uncharacterized protein. (638 aa)
A0A316UB97Uncharacterized protein. (389 aa)
A0A316UBG8Uncharacterized protein. (648 aa)
A0A316UBR0Uncharacterized protein. (856 aa)
A0A316UBT4DNA repair exonuclease. (874 aa)
A0A316UBU0DNA helicase; Belongs to the MCM family. (731 aa)
A0A316UBU8MutL_C domain-containing protein. (1067 aa)
A0A316UBV5Uncharacterized protein. (862 aa)
A0A316UC36DNA/RNA polymerase. (540 aa)
A0A316UC71DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (247 aa)
A0A316UCG5DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1188 aa)
A0A316UCK4DNA ligase/mRNA capping enzyme. (481 aa)
A0A316UCQ8Uncharacterized protein. (762 aa)
A0A316UCT8Replication factor C subunit 1. (1026 aa)
A0A316UD07P-loop containing nucleoside triphosphate hydrolase protein. (252 aa)
A0A316UD24Rad1-domain-containing protein. (467 aa)
A0A316UD46Putative DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR). (991 aa)
A0A316UD50Uncharacterized protein. (642 aa)
A0A316UDB6Uncharacterized protein. (919 aa)
A0A316UDG3Uncharacterized protein. (733 aa)
A0A316UDI1DNA_MISMATCH_REPAIR_2 domain-containing protein. (1743 aa)
A0A316UDQ8Uncharacterized protein. (682 aa)
A0A316UDR8DNA/RNA polymerase. (745 aa)
A0A316UE21P-loop containing nucleoside triphosphate hydrolase protein. (372 aa)
A0A316UE22Pkinase-domain-containing protein. (733 aa)
A0A316UEJ8Pkinase-domain-containing protein. (1254 aa)
A0A316UEN1DNA helicase; Belongs to the MCM family. (1003 aa)
A0A316UET1Rad51-domain-containing protein. (170 aa)
A0A316UF20Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (401 aa)
A0A316UF35SPOC domain-like protein. (917 aa)
A0A316UF90Uncharacterized protein. (1080 aa)
A0A316UF92Checkpoint protein; Belongs to the HUS1 family. (275 aa)
A0A316UFA9Uncharacterized protein. (977 aa)
A0A316UFB3Pkinase-domain-containing protein. (392 aa)
A0A316UFD4DNA glycosylase. (666 aa)
A0A316UFI0Sld5 domain-containing protein. (245 aa)
A0A316UFL9Uncharacterized protein. (581 aa)
A0A316UFQ9Uncharacterized protein. (619 aa)
A0A316UFZ5DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (410 aa)
A0A316UG23XPGI domain-containing protein. (916 aa)
A0A316UG70Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (417 aa)
A0A316UG99Nucleic acid-binding protein. (144 aa)
A0A316UGB6DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2323 aa)
A0A316UGD6P-loop containing nucleoside triphosphate hydrolase protein. (714 aa)
A0A316UGN6Histone-fold-containing protein. (264 aa)
A0A316UGY6Uncharacterized protein. (937 aa)
A0A316UHC1ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (552 aa)
A0A316UI28Protein kinase domain-containing protein. (1325 aa)
A0A316UIT5Ribonuclease H-like protein. (182 aa)
A0A316UJK9DNA primase; Belongs to the eukaryotic-type primase small subunit family. (471 aa)
A0A316UJP0AAA domain-containing protein. (1035 aa)
A0A316UK18SAE2 domain-containing protein. (610 aa)
A0A316ULL4P-loop containing nucleoside triphosphate hydrolase protein. (1343 aa)
A0A316UM03Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1002 aa)
Your Current Organism:
Pseudomicrostroma glucosiphilum
NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718
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